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Ishioka Ishioka, Omachi Omachi, Sagawa Sagawa (2006)
Canine adiponectincDNA structure, mRNA expression in adipose tissues and reduced plasma levels in obesity, 80
F. Lago, C. Diéguez, J. Gómez-Reino, O. Gualillo (2007)
Adipokines as emerging mediators of immune response and inflammationNature Clinical Practice Rheumatology, 3
M. Tuck (2005)
Angiotensin-receptor blocking agents and the peroxisome proliferator-activated receptor-γ systemCurrent Hypertension Reports, 7
M. Schupp, J. Janke, R. Clasen, T. Unger, U. Kintscher (2004)
Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator–Activated Receptor-γ ActivityCirculation: Journal of the American Heart Association, 109
M. Banerji, N. Faridi, R. Atluri, R. Chaiken, H. Lebovitz (1999)
Body composition, visceral fat, leptin, and insulin resistance in Asian Indian men.The Journal of clinical endocrinology and metabolism, 84 1
Sethi Sethi, Vidal‐Puig Vidal‐Puig (2007)
Adipose tissue function and plasticity orchestrate nutritional adaptationJ Lipid Res, 48
Ishioka Ishioka, Hatai Hatai, Komabayashi Komabayashi (2005)
Diurnal variations of serum leptin in dogseffects of fasting and re-feeding, 169
M. Gordon, K. McKeever, C. Betros, H. Filho (2007)
Plasma leptin, ghrelin and adiponectin concentrations in young fit racehorses versus mature unfit standardbreds.Veterinary journal, 173 1
Steven Shea, Steven Shea, Michael Hilton, Michael Hilton, Christine Orlova, R. Ayers, Christos Mantzoros, Christos Mantzoros (2005)
Independent circadian and sleep/wake regulation of adipokines and glucose in humans.The Journal of clinical endocrinology and metabolism, 90 5
U. Romagnoli, E. Macchi, G. Romano, M. Motta, P. Accornero, M. Baratta (2007)
Leptin concentration in plasma and in milk during the interpartum period in the mare.Animal reproduction science, 97 1-2
M. Trujillo, P. Scherer (2006)
Adipose tissue-derived factors: impact on health and disease.Endocrine reviews, 27 7
K. Mather, Bahram Mirzamohammadi, A. Lteif, H. Steinberg, A. Baron (2002)
Endothelin contributes to basal vascular tone and endothelial dysfunction in human obesity and type 2 diabetes.Diabetes, 51 12
H. Behre, M. Simoni, E. Nieschlag (1997)
Strong association between serum levels of leptin and testosterone in menClinical Endocrinology, 47
C. Feldstein, Carlos Romero (2007)
Role of Endothelins in HypertensionAmerican Journal of Therapeutics, 14
P. Peake, A. Kriketos, L. Campbell, Yvonne Shen, J. Charlesworth (2005)
The metabolism of isoforms of human adiponectin: studies in human subjects and in experimental animals.European journal of endocrinology, 153 3
Barton Barton, Vos Vos, Shaw Shaw (2000)
Dysfunctional renal nitric oxide synthase as a determinant of salt‐sensitive hypertensionmechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and glomerulosclerosis, 11
B. Heidler, N. Parvizi, H. Sauerwein, R. Bruckmaier, U. Heintges, J. Aurich, C. Aurich (2003)
Effects of lactation on metabolic and reproductive hormones in Lipizzaner mares.Domestic animal endocrinology, 25 1
P. Scarpace, M. Matheny, N. Tümer (2001)
Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese ratsNeuroscience, 104
Okamoto Okamoto, Kihara Kihara, Funahashi Funahashi, Matsuzawa Matsuzawa, Libby Libby (2006)
Adiponectina key adipocytokine in metabolic syndrome, 110
S. Pratt, R. Geor, L. McCutcheon (2005)
Relationship of insulin sensitivity to aerobic capacity in Standardbred mares and geldingsEquine and Comparative Exercise Physiology, 2
Miho Iwase, Kazuhiro Kimura, Rika Komagome, Noriyasu Sasaki, Katumi Ishioka, T. Honjoh, Masayuki Saito (2000)
Sandwich enzyme-linked immunosorbent assay of canine leptin.The Journal of veterinary medical science, 62 2
J. Speakman, C. Hambly, Sharon Mitchell, E. Król (2007)
Animal models of obesityObesity Reviews, 8
S. Farooqi, S. O’Rahilly (2006)
Genetics of obesity in humans.Endocrine reviews, 27 7
S. Thiess, C. Becskei, K. Tomsa, Thomas Lutz, M. Wanner (2004)
Effects of high carbohydrate and high fat diet on plasma metabolite levels and on iv glucose tolerance test in intact and neutered male catsJournal of Feline Medicine and Surgery, 6
Trujillo Trujillo, Scherer Scherer (2006)
Adipose tissue‐derived factorsimpact on health and disease, 27
Meier Meier, Gressner Gressner (2004)
Endocrine regulation of energy metabolismreview of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin, 50
E. Salimei, G. Varisco, F. Rosi (2002)
Major constituents, leptin, and non-protein nitrogen compounds in mares' colostrum and milk.Reproduction, nutrition, development, 42 1
P. Scarpace, M. Matheny, Robin Moore, N. Tümer (2000)
Impaired leptin responsiveness in aged rats.Diabetes, 49 3
K. Hotta, T. Funahashi, N. Bodkin, H. Ortmeyer, Y. Arita, B. Hansen, Y. Matsuzawa (2001)
Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.Diabetes, 50 5
A. Schäffler, J. Schölmerich, B. Salzberger (2007)
Adipose tissue as an immunological organ: Toll-like receptors, C1q/TNFs and CTRPs.Trends in immunology, 28 9
Mark Mark, Correia Correia, Rahmouni Rahmouni, Haynes Haynes (2002)
Selective leptin resistancea new concept in leptin physiology with cardiovascular implications, 20
M. Cartwright, T. Tchkonia, J. Kirkland (2007)
Aging in adipocytes: Potential impact of inherent, depot-specific mechanismsExperimental Gerontology, 42
Neel Neel (1962)
Diabetes mellitusa “thrifty” genotype rendered detrimental by “progress”?, 14
P. Scarpace, N. Tümer (2001)
Peripheral and hypothalamic leptin resistance with age-related obesityPhysiology & Behavior, 74
N. Nishii, M. Takasu, Y. Ohba, S. Maeda, K. Kitoh, Y. Ohtsuka, T. Honjo, M. Saito, H. Kitagawa (2006)
Effects of administration of glucocorticoids and feeding status on plasma leptin concentrations in dogs.American journal of veterinary research, 67 2
S. Bouret, Shin Draper, R. Simerly (2004)
Trophic Action of Leptin on Hypothalamic Neurons That Regulate FeedingScience, 304
S. Engeli, J. Böhnke, K. Gorzelniak, J. Janke, P. Schling, M. Bader, F. Luft, Arya Sharma (2005)
Weight Loss and the Renin-Angiotensin-Aldosterone SystemHypertension, 45
Kelesidis Kelesidis, Kelesidis Kelesidis, Mantzoros Mantzoros (2006)
Adiponectin and cancera systematic review, 94
R. Ahima, D. Prabakaran, C. Mantzoros, D. Qu, B. Lowell, E. Maratos-Flier, J. Flier (1996)
Role of leptin in the neuroendocrine response to fastingNature, 382
Barry Goldstein, Rosario Scalia (2004)
Adiponectin: A novel adipokine linking adipocytes and vascular function.The Journal of clinical endocrinology and metabolism, 89 6
N. Frank, S. Elliott, Laura Brandt, D. Keisler (2006)
Physical characteristics, blood hormone concentrations, and plasma lipid concentrations in obese horses with insulin resistance.Journal of the American Veterinary Medical Association, 228 9
P. Shah (2007)
Innate immune pathway links obesity to insulin resistance.Circulation research, 100 11
Simpson Simpson, Singh Singh (2008)
Effects of exercise on adiponectina systematic review, 16
J. Cartmill, D. Thompson, W. Storer, J. Crowley, N. Huff, C. Waller (2005)
Effect of dexamethasone, feeding time, and insulin infusion on leptin concentrations in stallions.Journal of animal science, 83 8
M. Heek, D. Mullins, M. Wirth, M. Graziano, A. Fawzi, D. Compton, C. France, L. Hoos, R. Casale, E. Sybertz, C. Strader, H. Davis (1996)
The relationship of tissue localization, distribution and turnover to feeding after intraperitoneal 125I-leptin administration to ob/ob and db/db mice.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 28 12
P. Buff, C. Morrison, V. Ganjam, D. Keisler (2005)
Effects of short-term feed deprivation and melatonin implants on circadian patterns of leptin in the horse.Journal of animal science, 83 5
T. Komatsu, F. Itoh, K. Hodate, S. Hazegawa, Y. Obara, S. Kushibiki (2005)
Gene expression of resistin and TNF-α in adipose tissue of Japanese Black steers and Holstein steersAnimal Science Journal, 76
Engeli Engeli, Schling Schling, Gorzelniak Gorzelniak (2003)
The adipose‐tissue renin‐angiotensin‐aldosterone systemrole in the metabolic syndrome?, 35
Zhuo-Wei Wang, W. Pan, Y. Lee, T. Kakuma, Yan-Ting Zhou, R. Unger (2001)
The role of leptin resistance in the lipid abnormalities of agingThe FASEB Journal, 15
Leah Dimascio, C. Voermans, Mweia Uqoezwa, A. Duncan, Danhong Lu, Judy Wu, Uma Sankar, T. Reya (2007)
Identification of Adiponectin as a Novel Hemopoietic Stem Cell Growth Factor1The Journal of Immunology, 178
L. Tartaglia, M. Dembski, Xun Weng, N. Deng, J. Culpepper, R. Devos, G. Richards, L. Campfield, F. Clark, J. Deeds, C. Muir, Sean Sanker, A. Moriarty, K. Moore, J. Smutko, Gail Mays, Elizabeth Wool, Cheryl Monroe, R. Tepper (1995)
Identification and expression cloning of a leptin receptor, OB-RCell, 83
M. Barton, R. Carmona, J. Ortmann, J. Krieger, T. Traupe (2003)
Obesity-associated activation of angiotensin and endothelin in the cardiovascular system.The international journal of biochemistry & cell biology, 35 6
M. Hoenig, K. Thomaseth, M. Waldron, D. Ferguson (2009)
Insulin sensitivity, fat distribution, and adipocytokine response to different diets in lean and obese cats before and after weight loss (American Journal of Physiology Regulatory Integrative and Comparative Physiology (2007) 292, (R227-R234) 10.1152/ajpregu.00313.2006))American Journal of Physiology-regulatory Integrative and Comparative Physiology, 296
Appleton Appleton, Rand Rand, Sunvold Sunvold (2000)
Plasma leptin concentrations in catsreference range, effect of weight gain and relationship with adiposity as measured by dual energy X-ray absorptiometry, 2
Christian Bjørbæk, K. El-Haschimi, J. Frantz, J. Flier (1999)
The Role of SOCS-3 in Leptin Signaling and Leptin Resistance*The Journal of Biological Chemistry, 274
P. Trayhurn (2007)
Adipocyte biologyObesity Reviews, 8
M. Iwase, K. Kimura, N. Sasaki, R. Komagome, K. Ishioka, M. Morimatsu, T. Murakami, M. Saito (2000)
Canine leptin: cDNA cloning, expression and activity of recombinant protein.Research in veterinary science, 68 2
(2009)
The relationship of tissue localization, distribution and Vet Clin Pathol 38/2
R. Shibata, Yasuhiro Izumiya, Kaori Sato, Kyriakos Papanicolaou, S. Kihara, W. Colucci, F. Sam, N. Ouchi, K. Walsh (2007)
Adiponectin protects against the development of systolic dysfunction following myocardial infarction.Journal of molecular and cellular cardiology, 42 6
Martin Martin, Siliart Siliart, Dumon Dumon (2001)
Leptin, body fat content and energy expenditure in intact and gonadectomized adult catsa preliminary study, 85
Andrea Rossi, Y. Lombardo, J. Lacorte, A. Chicco, C. Rouault, G. Slama, S. Rizkalla (2005)
Dietary fish oil positively regulates plasma leptin and adiponectin levels in sucrose-fed, insulin-resistant rats.American journal of physiology. Regulatory, integrative and comparative physiology, 289 2
T. Komatsu, F. Itoh, S. Mikawa, K. Hodate (2003)
Gene expression of resistin in adipose tissue and mammary gland of lactating and non-lactating cows.The Journal of endocrinology, 178 3
J. Cartmill, D. Thompson, R. Vecchio, W. Storer, J. Crowley (2006)
Leptin secretion in horses: effects of dexamethasone, gender, and testosterone.Domestic animal endocrinology, 31 2
L. Martin, B. Siliart, H. Dumon, R. Backus, V. Biourge, P. Nguyen (2001)
Leptin, body fat content and energy expenditure in intact and gonadectomized adult cats: a preliminary study.Journal of animal physiology and animal nutrition, 85 7-8
D. Kapoor, S. Clarke, R. Stanworth, K. Channer, T. Jones (2007)
The effect of testosterone replacement therapy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes.European journal of endocrinology, 156 5
H. Katagiri, Tetsuya Yamada, Y. Oka (2007)
Adiposity and Cardiovascular Disorders: Disturbance of the Regulatory System Consisting of Humoral and Neuronal SignalsCirculation Research, 101
B. Spiegelman, S. Enerbäck (2006)
"The adipocyte: a multifunctional cell".Cell metabolism, 4 6
P. Dandona, A. Chaudhuri, H. Ghanim, P. Mohanty (2007)
Proinflammatory effects of glucose and anti-inflammatory effect of insulin: relevance to cardiovascular disease.The American journal of cardiology, 99 4A
K. Ishioka, A. Omachi, Mayumi Sagawa, H. Shibata, T. Honjoh, Kazuhiro Kimura, Masayuki Saito (2006)
Canine adiponectin: cDNA structure, mRNA expression in adipose tissues and reduced plasma levels in obesity.Research in veterinary science, 80 2
Schäffler Schäffler, Schölmerich Schölmerich, Salzberger Salzberger (2007)
Adipose tissue as an immunological organtoll-like receptors, C1q/TNFs and CTRPs, 28
Ishioka Ishioka, Hosoya Hosoya, Kitagawa Kitagawa (2007)
Plasma leptin concentration in dogseffects of body condition score, age, gender and breeds, 82
P. Scarpace, M. Matheny, Yi Zhang, N. Tümer, C. Frase, E. Shek, B. Hong, V. Prima, Sergei Zolotukhin (2002)
Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese ratsNeuropharmacology, 42
Masami Tanaka, S. Nakaya, T. Kumai, Minoru Watanabe, T. Tateishi, H. Shimizu, Shinichi Kobayashi (2002)
Effects of Estrogen on Serum Leptin Levels and Leptin mRNA Expression in Adipose Tissue in RatsHormone Research in Paediatrics, 56
Mohammed Bensaid, M. Gary‐Bobo, A. Esclangon, J. Maffrand, G. Fur, F. Oury-Donat, P. Soubrié (2003)
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells.Molecular pharmacology, 63 4
H. Shimizu, Y. Shimomura, Y. Nakanishi, T. Futawatari, K. Ohtani, N. Sato, M. Mori (1997)
Estrogen increases in vivo leptin production in rats and human subjects.The Journal of endocrinology, 154 2
K. Deichsel, J. Aurich (2005)
Lactation and lactational effects on metabolism and reproduction in the horse mareLivestock Production Science, 98
Houseknecht Houseknecht, Portocarrero Portocarrero (1998)
Leptin and its receptorsregulators of whole-body energy homeostasis, 15
Gábor Fésüs, G. Dubrovska, K. Gorzelniak, R. Kluge, Yu Huang, F. Luft, M. Gollasch (2007)
Adiponectin is a novel humoral vasodilator.Cardiovascular research, 75 4
Hattori Hattori, Akimoto Akimoto, Gross Gross, Hattori Hattori, Kasai Kasai (2005)
Angiotensin‐II‐induced oxidative stress elicits hypoadiponectinaemia in ratsDiabetologia, 48
L. Gentry, D. Thompson, G. Gentry, K. Davis, R. Godke, J. Cartmill (2002)
The relationship between body condition, leptin, and reproductive and hormonal characteristics of mares during the seasonal anovulatory period.Journal of animal science, 80 10
Iwase Iwase, Kimura Kimura, Sasaki Sasaki (2000)
Canine leptincDNA cloning, expression and activity of recombinant protein, 68
M. Gordon, K. McKeever (2005)
Diurnal variation of ghrelin, leptin, and adiponectin in Standardbred mares.Journal of animal science, 83 10
I. Jeusette, J. Detilleux, H. Shibata, M. Saito, T. Honjoh, A. Delobel, L. Istasse, M. Diez (2005)
Effects of chronic obesity and weight loss on plasma ghrelin and leptin concentrations in dogs.Research in veterinary science, 79 2
M. Radin, B. Holycross, C. Dumitrescu, R. Kelley, R. Altschuld (2008)
Leptin modulates the negative inotropic effect of interleukin-1β in cardiac myocytesMolecular and Cellular Biochemistry, 315
S. Javadi, L. Slingerland, Margreet Beek, P. Boer, W. Boer, J. Mol, A. Rijnberk, H. Kooistra (2004)
Plasma renin activity and plasma concentrations of aldosterone, cortisol, adrenocorticotropic hormone, and alpha-melanocyte-stimulating hormone in healthy cats.Journal of veterinary internal medicine, 18 5
James Hill (2006)
Understanding and addressing the epidemic of obesity: an energy balance perspective.Endocrine reviews, 27 7
G. Sweeney (2002)
Leptin signalling.Cellular signalling, 14 8
C. Gayet, V. Leray, M. Saito, B. Siliart, P. Nguyen (2007)
The effects of obesity-associated insulin resistance on mRNA expression of peroxisome proliferator-activated receptor-γ target genes, in dogsBritish Journal of Nutrition, 98
M. Radin, Y. Chu, T. Hoepf, S. Mccune (1993)
Treatment of obese female and male SHHF/Mcc-fa(cp) rats with antihypertensive drugs, nifedipine and enalapril: effects on body weight, fat distribution, insulin resistance and systolic pressure.Obesity research, 1 6
Cartmill Cartmill, Thompson Thompson, Del Vecchio Del Vecchio, Storer Storer, Crowley Crowley (2006)
Leptin secretion in horseseffects of dexamethasone, gender, and testosterone, 31
J. Bruun, A. Lihn, C. Verdich, S. Pedersen, S. Toubro, A. Astrup, B. Richelsen (2003)
Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.American journal of physiology. Endocrinology and metabolism, 285 3
Ouchi Ouchi, Kihara Kihara, Arita Arita (1999)
Novel modulator for endothelial adhesion moleculesadipocyte-derived plasma protein adiponectin, 100
G. Piccione, C. Bertolucci, A. Foá, G. Caola (2004)
Influence of Fasting and Exercise on the Daily Rhythm of Serum Leptin in the HorseChronobiology International, 21
T. Pischon, G. Hotamisligil, E. Rimm (2003)
Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year.Clinical chemistry, 49 4
Pischon Pischon, Hotamisligil Hotamisligil, Rimm Rimm (2003)
Adiponectinstability in plasma over 36 hours and within-person variation over 1 year, 40
A. Omachi, K. Ishioka, Akihiro Uozumi, A. Kamikawa, Chitoku Toda, Kazuhiro Kimura, Masayuki Saito (2007)
Beta3-adrenoceptor agonist AJ-9677 reduces body fat in obese beagles.Research in veterinary science, 83 1
E. Hu, P. Liang, B. Spiegelman (1996)
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity (*)The Journal of Biological Chemistry, 271
M. Moore, K. Kimura, H. Shibata, T. Honjoh, M. Saito, Carrie Everett, Marta Smith, A. Cherrington (2005)
Portal 5-hydroxytryptophan infusion enhances glucose disposal in conscious dogs.American journal of physiology. Endocrinology and metabolism, 289 2
R. Backus, P. Havel, R. Gingerich, Q. Rogers (2000)
Relationship between serum leptin immunoreactivity and body fat mass as estimated by use of a novel gas-phase Fourier transform infrared spectroscopy deuterium dilution method in cats.American journal of veterinary research, 61 7
C. McManus, B. Fitzgerald (2000)
Effects of a single day of feed restriction on changes in serum leptin, gonadotropins, prolactin, and metabolites in aged and young mares.Domestic animal endocrinology, 19 1
A. Xu, Kok Chan, R. Hoo, Yu Wang, K. Tan, Jialiang Zhang, Baoying Chen, M. Lam, C. Tse, G. Cooper, K. Lam (2005)
Testosterone Selectively Reduces the High Molecular Weight Form of Adiponectin by Inhibiting Its Secretion from Adipocytes*Journal of Biological Chemistry, 280
Cnop Cnop, Havel Havel, Utzschneider Utzschneider (2003)
Relationship of adiponectin to body fat distribution, insulin sensitivity, and plasma lipoproteinsevidence for independent roles of age and sex, 46
M. Sánchez-Rodríguez, A. García-Sánchez, R. Retana-Ugalde, V. Mendoza-Núñez (2000)
Serum leptin levels and blood pressure in the overweight elderly.Archives of medical research, 31 4
Hiroyuki Ebinuma, O. Miyazaki, H. Yago, K. Hara, T. Yamauchi, T. Kadowaki (2006)
A novel ELISA system for selective measurement of human adiponectin multimers by using proteases.Clinica chimica acta; international journal of clinical chemistry, 372 1-2
Katagiri Katagiri, Yamada Yamada, Oka Oka (2007)
Adiposity and cardiovascular disordersdisturbance of the regulatory system consisting of humoral and neuronal signals, 101
K. Ohashi, N. Ouchi, S. Kihara, T. Funahashi, Tadashi Nakamura, S. Sumitsuji, T. Kawamoto, S. Matsumoto, H. Nagaretani, M. Kumada, Y. Okamoto, H. Nishizawa, K. Kishida, N. Maeda, H. Hiraoka, Y. Iwashima, K. Ishikawa, M. Ohishi, T. Katsuya, H. Rakugi, T. Ogihara, Y. Matsuzawa (2004)
Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease.Journal of the American College of Cardiology, 43 7
I. Gabriely, X. Ma, Xiao Yang, L. Rossetti, N. Barzilai (2002)
Leptin resistance during aging is independent of fat mass.Diabetes, 51 4
De Cavanagh De Cavanagh, Piotrkowski Piotrkowski, Fraga Fraga (2007)
The interaction between the renin‐angiotensin system and peroxisome proliferator activated receptorsa hypothesis including the participation of mitochondria in aging, 12
I. Kelesidis, T. Kelesidis, C. Mantzoros (2006)
Adiponectin and cancer: a systematic reviewBritish Journal of Cancer, 94
K. Ishioka, Kenji Hosoya, Hitoshi Kitagawa, H. Shibata, T. Honjoh, Kazuhiro Kimura, Masayuki Saito (2007)
Plasma leptin concentration in dogs: effects of body condition score, age, gender and breeds.Research in veterinary science, 82 1
Barb Barb, Williams Williams, Neuwirth Neuwirth, Mantzoros Mantzoros (2007)
Adiponectin in relation to malignanciesa review of existing basic research and clinical evidence, 86
P. Fischer-Posovszky, M. Wabitsch, Z. Hochberg (2007)
Endocrinology of Adipose Tissue - An UpdateHormone and Metabolic Research, 39
M. Kellerer, M. Koch, E. Metzinger, J. Mushack, Edison Capp, Hans Häring (1997)
Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathwaysDiabetologia, 40
Hill Hill (2006)
Understanding and addressing the epidemic of obesityan energy balance perspective, 27
H. Baumann, K. Morella, David WHITEt, Marlene Dembskii, P. Bailon, Hongkyun Kim, Chun-fai Lai, Louis TARTAGLIAt (1996)
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.Proceedings of the National Academy of Sciences of the United States of America, 93 16
F. Ovalle, R. Azziz (2002)
Insulin resistance, polycystic ovary syndrome, and type 2 diabetes mellitus.Fertility and sterility, 77 6
Christian Bjørbæk, S. Uotani, B. Silva, J. Flier (1997)
Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor*The Journal of Biological Chemistry, 272
S. Carlson, Jonathon Shelton, C. White, J. Wyss (2000)
Elevated sympathetic activity contributes to hypertension and salt sensitivity in diabetic obese Zucker rats.Hypertension, 35 1 Pt 2
Saleri Saleri, Tirelli Tirelli, Grasselli Grasselli, Dondi Dondi, Arisi Arisi (2003)
Sexual dimorphism of blood leptin levels in dog (in Italian)Veterinaria (Cremona), 17
R. Backus, N. Cave, D. Keisler (2007)
Gonadectomy and high dietary fat but not high dietary carbohydrate induce gains in body weight and fat of domestic catsBritish Journal of Nutrition, 98
Lucile Martin, B. Siliart, H. Dumon, P. Nguyen (2006)
Spontaneous hormonal variations in male cats following gonadectomyJournal of Feline Medicine and Surgery, 8
M. Hoenig, D. Ferguson (2002)
Effects of neutering on hormonal concentrations and energy requirements in male and female cats.American journal of veterinary research, 63 5
J. Corre, Corinne Barreau, B. Cousin, J. Chavoin, D. Caton, G. Fournial, L. Pénicaud, L. Casteilla, P. Laharrague (2006)
Human subcutaneous adipose cells support complete differentiation but not self‐renewal of hematopoietic progenitorsJournal of Cellular Physiology, 208
Belaid‐Choucair Belaid‐Choucair, Lepelletier Lepelletier, Poncin Poncin (2008)
Human bone marrow adipocytes block granulopoiesis through neuropilin‐1 induced G‐CSF inhibitionStem Cells, 26
J. Cartmill, D. Thompson, W. Storer, L. Gentry, N. Huff (2003)
Endocrine responses in mares and geldings with high body condition scores grouped by high vs. low resting leptin concentrations.Journal of animal science, 81 9
Z. Yilmaz, Y. Ilcol, E. Golcu (2007)
Serum leptin and ghrelin levels in response to methylprednisolone injection in healthy dogs.Research in veterinary science, 82 2
A. Malin, Q. Dai, Herbert Yu, X. Shu, F. Jin, Yu-Tang Gao, W. Zheng (2004)
Evaluation of the synergistic effect of insulin resistance and insulin‐like growth factors on the risk of breast carcinomaCancer, 100
M. Diez, P. Nguyen (2006)
The epidemiology of canine and feline obesity, 1
M. Correia, K. Rahmouni (2006)
Role of leptin in the cardiovascular and endocrine complications of metabolic syndromeDiabetes, 8
K. Nagao, N. Inoue, Yu-ming Wang, T. Yanagita (2003)
Conjugated linoleic acid enhances plasma adiponectin level and alleviates hyperinsulinemia and hypertension in Zucker diabetic fatty (fa/fa) rats.Biochemical and biophysical research communications, 310 2
L. Clarke, V. Ganjam, B. Fichtenbaum, D. Hatfield, H. Garner (1988)
Effect of feeding on renin-angiotensin-aldosterone system of the horse.The American journal of physiology, 254 3 Pt 2
K. Ishioka, M. Soliman, T. Honjoh, H. Shibata, Kazuhiro Kimura, M. Saito (2002)
Dexamethasone increases serum leptin concentration in dogs.Veterinary journal, 164 3
M. Dai, T. Xia, X. Chen, L. Gan, S. Feng, H. Qiu, Y. Peng, Z. Yang (2006)
Cloning and characterization of porcine resistin gene.Domestic animal endocrinology, 30 2
(2009)
Vet Clin Pathol American Society for Veterinary Clinical Pathology
N. Eikelis, M. Schlaich, A. Aggarwal, D. Kaye, M. Esler (2003)
Interactions Between Leptin and the Human Sympathetic Nervous SystemHypertension: Journal of the American Heart Association, 41
J. Henegar, S. Bigler, Lisa Henegar, S. Tyagi, J. Hall (2001)
Functional and structural changes in the kidney in the early stages of obesity.Journal of the American Society of Nephrology : JASN, 12 6
C. Wyse, KA McNie, VJ Tannahil, J. Murray, Sandy Love (2008)
Prevalence of obesity in riding horses in ScotlandVeterinary Record, 162
A. German (2006)
The growing problem of obesity in dogs and cats.The Journal of nutrition, 136 7 Suppl
M. Tsunoda, Naoki Kobayashi, T. Ide, M. Utsumi, Michiaki Nagasawa, K. Murakami (2008)
A novel PPARalpha agonist ameliorates insulin resistance in dogs fed a high-fat diet.American journal of physiology. Endocrinology and metabolism, 294 5
G. Licata, M. Volpe, R. Scaglione, S. Rubattu (1994)
Salt‐Regulating Hormones in Young Normotensive Obese Subjects: Effects of Saline LoadHypertension, 23
M. Cnop, M. Cnop, P. Havel, K. Utzschneider, Daniel Carr, M. Sinha, E. Boyko, B. Retzlaff, R. Knopp, J. Brunzell, S. Kahn (2003)
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sexDiabetologia, 46
M. Yılmaz, A. Sonmez, K. Çağlar, T. Celik, M. Yenıcesu, T. Eyileten, C. Açikel, Y. Oğuz, I. Yavuz, A. Vural (2007)
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndromeNephrology, 12
Bruun Bruun, Lihn Lihn, Verdich Verdich (2003)
Regulation of adiponectin by adipose tissue‐derived cytokinesin vivo and in vitro investigations in humans, 285
A. Mark, M. Correia, K. Rahmouni, W. Haynes (2002)
Selective leptin resistance: a new concept in leptin physiology with cardiovascular implications.Journal of hypertension, 20 7
S. Steelman, E. Michael-Eller, P. Gibbs, G. Potter (2006)
Meal size and feeding frequency influence serum leptin concentration in yearling horses.Journal of animal science, 84 9
Y. Arita, S. Kihara, N. Ouchi, Masahiko Takahashi, K. Maeda, J. Miyagawa, K. Hotta, I. Shimomura, Tadashi Nakamura, K. Miyaoka, H. Kuriyama, M. Nishida, S. Yamashita, K. Okubo, K. Matsubara, M. Muraguchi, Y. Ohmoto, T. Funahashi, Y. Matsuzawa (1999)
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity.Biochemical and biophysical research communications, 257 1
C. Garofalo, E. Surmacz (2006)
Leptin and cancerJournal of Cellular Physiology, 207
N. Rasouli, B. Molavi, S. Elbein, P. Kern (2007)
Ectopic fat accumulation and metabolic syndromeDiabetes, 9
N. Sasaki, H. Shibata, T. Honjoh, K. Kimura, M. Saito, I. Ohishi (2001)
CDNA cloning of feline leptin and its mRNA expression in adipose tissue.The Journal of veterinary medical science, 63 10
Peake Peake, Kriketos Kriketos, Campbell Campbell, Shen Shen, Charlesworth Charlesworth (2005)
The metabolism of isoforms of human adiponectinstudies in human subjects and in experimental animals, 153
Y. Okamoto, S. Kihara, T. Funahashi, Y. Matsuzawa, P. Libby (2006)
Adiponectin: a key adipocytokine in metabolic syndrome.Clinical science, 110 3
S. Hong, C. Park, H. Seo, D. Oh, Y. Ro (2004)
Associations among plasma adiponectin, hypertension, left ventricular diastolic function and left ventricular mass indexBlood Pressure, 13
D. Laflamme (2006)
Understanding and managing obesity in dogs and cats.The Veterinary clinics of North America. Small animal practice, 36 6
S. Klein, S. Coppack, V. Mohamed-ali, M. Landt (1996)
Adipose Tissue Leptin Production and Plasma Leptin Kinetics in HumansDiabetes, 45
T. Yokota, K. Oritani, Isao Takahashi, J. Ishikawa, A. Matsuyama, N. Ouchi, S. Kihara, T. Funahashi, A. Tenner, Y. Tomiyama, Yuji Matsuzawa (2000)
Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages.Blood, 96 5
N. Nishii, Hiroyuki Nodake, M. Takasu, Okkar Soe, Y. Ohba, S. Maeda, Y. Ohtsuka, T. Honjo, M. Saito, H. Kitagawa (2006)
Postprandial changes in leptin concentrations of cerebrospinal fluid in dogs during development of obesity.American journal of veterinary research, 67 12
A. Caetano, D. Pomp, J. Murray, A. Bowling (1999)
Comparative mapping of 18 equine type I genes assigned by somatic cell hybrid analysisMammalian Genome, 10
D. Wunder, M. Yared, N. Bersinger, D. Widmer, R. Kretschmer, Martin Birkhäuser (2006)
Serum leptin and C-reactive protein levels in the physiological spontaneous menstrual cycle in reproductive age women.European journal of endocrinology, 155 1
K. Ishioka, H. Hatai, K. Komabayashi, M. Soliman, H. Shibata, T. Honjoh, K. Kimura, M. Saito (2005)
Diurnal variations of serum leptin in dogs: effects of fasting and re-feeding.Veterinary journal, 169 1
J. Neel (1962)
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?American journal of human genetics, 14
Kurt Kristensen, Steen Pedersen, Bjørn Richelsen (1999)
Regulation of leptin by steroid hormones in rat adipose tissue.Biochemical and biophysical research communications, 259 3
Jaswinder Sethi, A. Vidal-Puig (2007)
Thematic review series: Adipocyte Biology. Adipose tissue function and plasticity orchestrate nutritional adaptation Published, JLR Papers in Press, March 20, 2007.Journal of Lipid Research, 48
Ahren Ahren, Mansson Mansson, Gingerich Gingerich (1997)
Regulation of plasma leptin in miceinfluence of age, high-fat diet, and fasting, 273
D. Barb, Catherine Williams, Anke Neuwirth, C. Mantzoros (2007)
Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence.The American journal of clinical nutrition, 86 3
N. Ouchi, S. Kihara, Y. Arita, K. Maeda, H. Kuriyama, Y. Okamoto, K. Hotta, M. Nishida, Masahiko Takahashi, Tadashi Nakamura, S. Yamashita, T. Funahashi, Y. Matsuzawa (1999)
Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin.Circulation, 100 25
J. Heshka, P. Jones (2001)
A role for dietary fat in leptin receptor, OB-Rb, function.Life sciences, 69 9
Tatsuya Yamashita, Tatsuya Yamashita, T. Murakami, T. Murakami, Shizuka Otani, M. Kuwajima, K. Shima (1998)
Leptin receptor signal transduction: OBRa and OBRb of fa type.Biochemical and biophysical research communications, 246 3
R. Saleri, M. Tirelli, F. Grasselli, M. Dondi, M. Arisi (2003)
Sexual dimorphism of blood leptin levels in dog, 17
N. Hoggard, J. Mercer, D. Rayner, K. Moar, P. Trayhurn, L. Williams (1997)
Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization.Biochemical and biophysical research communications, 232 2
Yamashita Yamashita, Murakami Murakami, Otani Otani, Kuwajima Kuwajima, Shima Shima (1998)
Leptin receptor signal transductionOBRa and OBRb of fa type, 246
Yki‐Järvinen Yki‐Järvinen (2004)
ThiazolidinedionesN Engl J Med, 351
Daniel Castrogiovanni, M. Perelló, R. Gaillard, E. Spinedi (2003)
Modulatory role of testosterone in plasma leptin turnover in ratsEndocrine, 22
R. Vilà, C. Adán, I. Rafecas, J. Fernández‐López, X. Remesar, M. Alemany (1998)
Plasma leptin turnover rates in lean and obese Zucker rats.Endocrinology, 139 11
Diana Rubin, U. Helwig, M. Nothnagel, Nina Lemke, S. Schreiber, U. Fölsch, F. Döring, J. Schrezenmeir (2007)
Postprandial plasma adiponectin decreases after glucose and high fat meal and is independently associated with postprandial triacylglycerols but not with − 11388 promoter polymorphismBritish Journal of Nutrition, 99
K. Houseknecht, C. Portocarrero (1998)
Leptin and its receptors: regulators of whole-body energy homeostasis.Domestic animal endocrinology, 15 6
E. Cavanagh, Bárbara Piotrkowski, C. Fraga (2007)
The interaction between the renin-angiotensin system and peroxisome proliferator activated receptors: a hypothesis including the participation of mitochondria in aging.Frontiers in bioscience : a journal and virtual library, 12
M. Ibarra-Rubio, JoséCarlos Peńa, José Pedraza-Chaverrí (1989)
Kinetic and inhibitory characteristics of serum angiotensin-converting enzyme from nine mammalian species.Comparative biochemistry and physiology. B, Comparative biochemistry, 92 2
K. Rahmouni, A. Mark, W. Haynes, C. Sigmund (2004)
Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity.American journal of physiology. Endocrinology and metabolism, 286 6
Matthias Barton, I. Vos, Sidney Shaw, Peter Boer, L. d’Uscio, H. Gröne, Ton Rabelink, T. Lattmann, Pierre Moreau, T. Lüscher (2000)
Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension: mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and Glomerulosclerosis.Journal of the American Society of Nephrology : JASN, 11 5
Goldstein Goldstein, Scalia Scalia (2004)
Adiponectina novel adipokine linking adipocytes and vascular function, 89
A. Nagasawa, K. Fukui, Makiko Kojima, K. Kishida, N. Maeda, H. Nagaretani, T. Hibuse, H. Nishizawa, S. Kihara, M. Waki, K. Takamatsu, T. Funahashi, Y. Matsuzawa (2003)
Divergent effects of soy protein diet on the expression of adipocytokines.Biochemical and biophysical research communications, 311 4
Buff Buff, Dodds Dodds, Morrison Morrison (2002)
Leptin in horsestissue localization and relationship between peripheral concentrations of leptin and body condition, 80
E. Berg, D. McNamara, D. Keisler (2007)
Endocrine profiles of periparturient mares and their foals.Journal of animal science, 85 7
W. Storer, D. Thompson, C. Waller, J. Cartmill (2007)
Hormonal patterns in normal and hyperleptinemic mares in response to three common feeding-housing regimens.Journal of animal science, 85 11
M. Zeyda, D. Farmer, J. Todoric, O. Aszmann, M. Speiser, G. Györi, G. Zlabinger, T. Stulnig (2007)
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator productionInternational Journal of Obesity, 31
E. Zini, P. Linscheid, M. Franchini, K. Kaufmann, E. Monnais, A. Kutter, M. Ackermann, T. Lutz, C. Reusch (2009)
Partial sequencing and expression of genes involved in glucose metabolism in adipose tissues and skeletal muscle of healthy cats.Veterinary journal, 180 1
C. Vecchione, A. Maffei, Salvatore Colella, A. Aretini, R. Poulet, G. Frati, M. Gentile, L. Fratta, V. Trimarco, B. Trimarco, G. Lembo (2002)
Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.Diabetes, 51 1
Cartwright Cartwright, Tchkonia Tchkonia, Kirkland Kirkland (2007)
Aging in adipocytespotential impact of inherent depot-specific mechanisms, 42
Spiegelman Spiegelman, Enerbäck Enerbäck (2006)
The adipocytea multifunctional cell, 4
M. Lazar (2007)
Resistin- and Obesity-associated metabolic diseases.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 39 10
C. Waller, Donald Thompson, J. Cartmill, W. Storer, N. Huff (2006)
Reproduction in high body condition mares with high versus low leptin concentrations.Theriogenology, 66 4
Radin Radin, Chu Chu, Hoepf Hoepf, McCune McCune (1993)
Treatment of obese female and male SHHF/Mcc‐ facp rats with nifedipine and enalaprileffects on body weight, fat distribution, insulin resistance and systolic pressure, 1
Preston Buff, A. Dodds, C. Morrison, N. Whitley, E. McFadin, J. Daniel, Jean Djiane, D. Keisler (2002)
Leptin in horses: tissue localization and relationship between peripheral concentrations of leptin and body condition.Journal of animal science, 80 11
V. Cunha, D. Tham, B. Martin-McNulty, G. Deng, Jerrick Ho, D. Wilson, J. Rutledge, R. Vergona, M. Sullivan, Yi-xin Wang (2005)
Enalapril attenuates angiotensin II-induced atherosclerosis and vascular inflammation.Atherosclerosis, 178 1
M. Sagawa, F. Nakadomo, T. Honjoh, K. Ishioka, M. Saito (2002)
Correlation between plasma leptin concentration and body fat content in dogs.American journal of veterinary research, 63 1
R. Clasen, M. Schupp, A. Foryst-Ludwig, C. Sprang, M. Clemenz, M. Krikov, C. Thöne-Reineke, T. Unger, U. Kintscher (2005)
PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin.Hypertension, 46 1
J. Małyszko, J. Małyszko, P. Koźmiński, K. Pawlak, M. Myśliwiec (2008)
Adipokines, Linking Adipocytes and Vascular Function in Hemodialyzed Patients, May Also Be Possibly Related to CD146, a Novel Adhesion MoleculeClinical and Applied Thrombosis/Hemostasis, 14
M. Radin, B. Holycross, T. Hoepf, S. Mccune (2008)
Salt-Induced Cardiac Hypertrophy Is Independent of Blood Pressure and Endothelin in Obese, Heart Failure-Prone SHHF RatsClinical and Experimental Hypertension, 30
W. Pan, A. Kastin (2007)
Adipokines and the blood-brain barrierPeptides, 28
Q. Lam, Liwei Lu (2007)
Role of leptin in immunity.Cellular & molecular immunology, 4 1
(2004)
N Engl J Med
Brandon Brunson, Q. Zhong, K. Clarke, Deepa Bedi, T. Braden, E. Santen, R. Judd (2007)
Serum concentrations of adiponectin and characterization of adiponectin protein complexes in dogs.American journal of veterinary research, 68 1
T. Hopkins, N. Ouchi, R. Shibata, K. Walsh (2007)
Adiponectin actions in the cardiovascular system.Cardiovascular research, 74 1
Z. Belaid-Choucair, Y. Lepelletier, Géraldine Poncin, A. Thiry, C. Humblet, M. Maachi, Aurore Beaulieu, E. Schneider, A. Briquet, P. Mineur, C. Lambert, D. Mendes-da-Cruz, M. Ahui, V. Asnafi, M. Dy, J. Boniver, B. Nusgens, O. Hermine, M. Defresne (2008)
Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin‐1‐Induced Granulocyte Colony‐Stimulating Factor InhibitionSTEM CELLS, 26
C. Kearns, K. McKeever, V. Roegner, S. Brady, K. Malinowski (2006)
Adiponectin and leptin are related to fat mass in horses.Veterinary journal, 172 3
F. Kim, Matilda Pham, I. Luttrell, D. Bannerman, J. Tupper, J. Thaler, T. Hawn, E. Raines, M. Schwartz (2007)
Toll-Like Receptor-4 Mediates Vascular Inflammation and Insulin Resistance in Diet-Induced ObesityCirculation Research, 100
S. Furukawa, T. Fujita, M. Shimabukuro, M. Iwaki, Yukio Yamada, Y. Nakajima, O. Nakayama, M. Makishima, M. Matsuda, I. Shimomura (2004)
Increased oxidative stress in obesity and its impact on metabolic syndrome.The Journal of clinical investigation, 114 12
Vecchione Vecchione, Maffei Maffei, Colella Colella (2002)
Leptin effect on endothelial nitric oxide synthase phosphorylation pathwayDiabetes, 51
N. Ouchi, M. Ohishi, S. Kihara, T. Funahashi, Tadashi Nakamura, H. Nagaretani, M. Kumada, K. Ohashi, Y. Okamoto, H. Nishizawa, K. Kishida, N. Maeda, A. Nagasawa, Hideki Kobayashi, H. Hiraoka, N. Komai, Masaharu Kaibe, H. Rakugi, T. Ogihara, Y. Matsuzawa (2003)
Association of Hypoadiponectinemia With Impaired VasoreactivityHypertension: Journal of The American Heart Association, 42
Wallace Am (2000)
Measurement of leptin and leptin binding in the human circulationAnnals of Clinical Biochemistry, 37
Shibata Shibata, Sasaki Sasaki, Honjoh Honjoh (2003)
Feline leptinimmunogenic and biological activities of the recombinant protein, and its measurement by ELISA, 65
P. Enriori, A. Evans, P. Sinnayah, M. Cowley (2006)
Leptin Resistance and ObesityObesity, 14
D. Appleton, JS Rand, GD Sunvold (2002)
Plasma Leptin Concentrations are Independently Associated with Insulin Sensitivity in Lean and Overweight CatsJournal of Feline Medicine and Surgery, 4
N. Barzilai, Swati Banerjee, M. Hawkins, Wei Chen, L. Rossetti (1998)
Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat.The Journal of clinical investigation, 101 7
Rita Miller, L. Lehmkuhl, D. Smeak, S. Dibartola, Judith Radin (1999)
Effect of enalapril on blood pressure, renal function, and the renin-angiotensin-aldosterone system in cats with autosomal dominant polycystic kidney disease.American journal of veterinary research, 60 12
T. Matsuoka, M. Tahara, Takeshi Yokoi, Nobuyuki Masumoto, Takashi Takeda, Masaaki Yamaguchi, Keiichi Tasaka, Hirohisa Kurachi, Yuji Murata (1999)
Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte.Biochemical and biophysical research communications, 256 3
N. Ghilardi, Sandra Ziegler, A. Wiestner, R. Stoffel, M. Heim, R. Skoda (1996)
Defective STAT signaling by the leptin receptor in diabetic mice.Proceedings of the National Academy of Sciences of the United States of America, 93 13
L. Vona-Davis, D. Rose (2007)
Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression.Endocrine-related cancer, 14 2
(2003)
Structure–function studies of the adipocyte-secreted hormone Acrp30/ adiponectin. Implications for metabolic regulation and bioactivity
M. Sinha, T. Songer, Q. Xiao, J. Sloan, Jin Wang, Shaoquen Ji, W. Alborn, R. Davis, M. Swarbrick, K. Stanhope, B. Wolfe, P. Havel, T. Schraw, R. Konrad, P. Scherer, J. Mistry (2007)
Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA.Clinical chemistry, 53 12
M. Gordon, K. McKeever, C. Betros, H. Filho (2007)
Exercise-induced alterations in plasma concentrations of ghrelin, adiponectin, leptin, glucose, insulin, and cortisol in horses.Veterinary journal, 173 3
Hua Li, M. Matheny, M. Nicolson, N. Türner, P. Scarpace (1997)
Leptin Gene Expression Increases With Age Independent of Increasing Adiposity in RatsDiabetes, 46
R. Clasen, M. Schupp, A. Foryst-Ludwig, C. Sprang, M. Clemenz, M. Krikov, C. Thöne-Reineke, T. Unger, U. Kintscher (2005)
PPAR&ggr;-Activating Angiotensin Type-1 Receptor Blockers Induce AdiponectinHypertension, 46
R. Ostlund, Joseph Yang, S. Klein, R. Gingerich (1996)
Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates.The Journal of clinical endocrinology and metabolism, 81 11
T. Kadowaki, T. Yamauchi (2005)
Adiponectin and adiponectin receptors.Endocrine reviews, 26 3
U. Meier, A. Gressner (2004)
Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin.Clinical chemistry, 50 9
M. Wabitsch, Per Jensen, W. Blum, C. Christoffersen, P. Englaro, E. Heinze, W. Rascher, W. Teller, H. Tornqvist, H. Hauner (1996)
Insulin and Cortisol Promote Leptin Production in Cultured Human Fat CellsDiabetes, 45
Christian Bjørbæk, J. Elmquist, J. Frantz, S. Shoelson, J. Flier (1998)
Identification of SOCS-3 as a potential mediator of central leptin resistance.Molecular cell, 1 4
B. Ahrén, S. Månsson, R. Gingerich, P. Havel (1997)
Regulation of plasma leptin in mice: influence of age, high-fat diet, and fasting.The American journal of physiology, 273 1 Pt 2
V. Calegari, M. Alves, P. Picardi, R. Inoue, K. Franchini, M. Saad, L. Velloso (2005)
Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems.Endocrinology, 146 2
I. Eisele, I. Wood, A. German, L. Hunter, P. Trayhurn (2005)
Adipokine Gene Expression in Dog Adipose Tissues and Dog White Adipocytes Differentiated in Primary CultureHormone and Metabolic Research, 37
Takashi Murakami, Tatsuya Yamashita, M. Iida, Masamichi Kuwajima, Kenji Shima (1997)
A short form of leptin receptor performs signal transduction.Biochemical and biophysical research communications, 231 1
M. Gordon, K. McKeever (2006)
Oral and intravenous carbohydrate challenges decrease active ghrelin concentrations and alter hormones related to control of energy metabolism in horses.Journal of animal science, 84 7
Margarethe Hoenig, Karl Thomaseth, M. Waldron, D. Ferguson (2007)
Insulin sensitivity, fat distribution, and adipocytokine response to different diets in lean and obese cats before and after weight loss.American journal of physiology. Regulatory, integrative and comparative physiology, 292 1
B. Fitzgerald, C. McManus (2000)
Photoperiodic Versus Metabolic Signals as Determinants of Seasonal Anestrus in the Mare1, 63
K. Ishioka, M. Soliman, M. Sagawa, F. Nakadomo, H. Shibata, T. Honjoh, A. Hashimoto, H. Kitamura, K. Kimura, M. Saito (2002)
Experimental and clinical studies on plasma leptin in obese dogs.The Journal of veterinary medical science, 64 4
I. Jeusette, Estelle Lhoest, L. Istasse, M. Diez (2005)
Influence of obesity on plasma lipid and lipoprotein concentrations in dogs.American journal of veterinary research, 66 1
M. Radin, B. Holycross, T. Hoepf, S. Mccune (2004)
Increased salt sensitivity secondary to leptin resistance in SHHF rats is mediated by endothelinMolecular and Cellular Biochemistry, 242
S. Engeli, P. Schling, K. Gorzelniak, M. Boschmann, J. Janke, G. Ailhaud, M. Teboul, F. Massiéra, Arya Sharma (2003)
The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome?The international journal of biochemistry & cell biology, 35 6
H. Shibata, N. Sasaki, T. Honjoh, I. Ohishi, M. Takiguchi, K. Ishioka, Mohamed Ahmed, M. Soliman, K. Kimura, M. Saito (2003)
Feline leptin: immunogenic and biological activities of the recombinant protein, and its measurement by ELISA.The Journal of veterinary medical science, 65 11
Junko Yamauchi, H. Osawa, T. Takasuka, M. Ochi, A. Murakami, Wataru Nishida, H. Onuma, Y. Takata, Y. Tabara, T. Miki, J. Ohashi, H. Makino (2008)
Serum resistin is reduced by glucose and meal loading in healthy human subjects.Metabolism: clinical and experimental, 57 2
Chien-ping Liang, Seongah Han, Takafumi Senokuchi, A. Tall (2007)
The Macrophage at the Crossroads of Insulin Resistance and AtherosclerosisCirculation Research, 100
M. Tuck (2005)
Angiotensin-receptor blocking agents and the peroxisome proliferator-activated receptor-gamma system.Current hypertension reports, 7 4
Y. Hattori, Kazumi Akimoto, Steven Gross, S. Hattori, K. Kasai (2005)
RETRACTED ARTICLE: Angiotensin-II-induced oxidative stress elicits hypoadiponectinaemia in ratsDiabetologia, 48
D. Appleton, J. Rand, G. Sunvold (2000)
Plasma Leptin Concentrations in Cats: Reference Range, Effect of Weight Gain and Relationship with Adiposity as Measured by Dual Energy X-Ray AbsorptiometryJournal of Feline Medicine and Surgery, 2
Kylie Simpson, M. Singh (2008)
Effects of Exercise on Adiponectin: A Systematic ReviewObesity, 16
Abstract: In addition to its role as an energy storage depot, adipose tissue is now recognized as a complex endocrine organ. Adipose tissue releases a variety of factors, termed adipokines, that regulate energy metabolism, cardiovascular function, reproductive status, and immune function. Some of the better‐studied adipokines include leptin, adiponectin, and components of the renin‐angiotensin system such as angiotensinogen. The function of more recently discovered adipokines such as resistin are under intense scrutiny. Abnormal production or regulation of adipokines occurs in obese individuals and is implicated in the development of a variety of associated co‐morbidities including metabolic syndrome, type 2 diabetes, atherosclerosis, heart disease, and cancer in people, although evaluation in domestic species is just beginning. Adipokines are now being examined as potential biomarkers for risk assessment for development of complications related to obesity. This article summarizes the function and regulation of some better‐characterized adipokines. It also reviews the current information on the characterization of adipokines in some domestic species in which rates of obesity and obesity‐related disorders are increasing, such as the dog, cat, and horse.
Veterinary Clinical Pathology – Wiley
Published: Jun 1, 2009
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