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Basal cell epithelioma in a chronic leg ulcer

Basal cell epithelioma in a chronic leg ulcer D.A.BURNS AND CD. CALNAN Department of Dermatology, The Royal Free Hospital, Pond Street, London NW3 2QG Accepted for publication 6 March 1978 History Mrs H.B., aged 79. This patient gave a 20 year history of ulceration on the medial aspect of the right leg in the region of the medial malleolus. There were bilateral venous varicosities, but no definite history of a preceding deep vein thrombosis. No history of ingestion of arsenicals could be obtained. Examination Mild bilateral venous varicosities. When first seen there was an ulcer in the region ofthe right medial malleolus with adjacent scar tissue. The affected area was heavily crusted and its border appeared indistinct. However, following debridement a distinctly elevated margin became apparent (Fig. i). Investigations X-ray of the right leg—osteoporosis of the bones, but no other abnormality was seen. Patch tests—positive reaction to Ethylenediamine. Histopathology. Biopsy of the elevated margin of this lesion in three places showed the changes of basal cell epithelioma (Fig. 2). Tissue from the scarred area and from the margin of the ulcer did not show any evidence of neoplasia. Treatment The ulcerated area healed spontaneously with bed rest. We plan to treat only the margin ofthe affected http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical & Experimental Dermatology Wiley

Basal cell epithelioma in a chronic leg ulcer

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References (6)

Publisher
Wiley
Copyright
Copyright © 1978 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0307-6938
eISSN
1365-2230
DOI
10.1111/j.1365-2230.1978.tb01525.x
Publisher site
See Article on Publisher Site

Abstract

D.A.BURNS AND CD. CALNAN Department of Dermatology, The Royal Free Hospital, Pond Street, London NW3 2QG Accepted for publication 6 March 1978 History Mrs H.B., aged 79. This patient gave a 20 year history of ulceration on the medial aspect of the right leg in the region of the medial malleolus. There were bilateral venous varicosities, but no definite history of a preceding deep vein thrombosis. No history of ingestion of arsenicals could be obtained. Examination Mild bilateral venous varicosities. When first seen there was an ulcer in the region ofthe right medial malleolus with adjacent scar tissue. The affected area was heavily crusted and its border appeared indistinct. However, following debridement a distinctly elevated margin became apparent (Fig. i). Investigations X-ray of the right leg—osteoporosis of the bones, but no other abnormality was seen. Patch tests—positive reaction to Ethylenediamine. Histopathology. Biopsy of the elevated margin of this lesion in three places showed the changes of basal cell epithelioma (Fig. 2). Tissue from the scarred area and from the margin of the ulcer did not show any evidence of neoplasia. Treatment The ulcerated area healed spontaneously with bed rest. We plan to treat only the margin ofthe affected

Journal

Clinical & Experimental Dermatology – Wiley

Published: Dec 1, 1978

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