Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/nitric-oxide-donors-as-treatment-for-grass-induced-acute-laminitis-in-1jd3xpSi7I
References (40)
-
K. Hinckley, S. Fearn, B. Howard, I. Henderson (1995)
Near infrared spectroscopy of pedal haemodynamics and oxygenation in normal and laminitic horses.Equine veterinary journal, 27 6
-
J. Elliott, Clare Bryant, J. Soydan (1994)
The role of nitric oxide in the responses of equine digital veins to vasodilator and vasoconstrictor agents.Equine veterinary journal, 26 5
-
R. Palmer, D. Ashton, S. Moncada (1988)
Vascular endothelial cells synthesize nitric oxide from L-arginineNature, 333
-
J. Vane, E. Änggård, R. Botting (1990)
Regulatory functions of the vascular endothelium.The New England journal of medicine, 323 1
-
S. Fickling, A. Leone, S. Nussey, P. Vallance, G. Whitley (1993)
Synthesis of NG, NG Dimethylarginine by Human Endothelial CellsEndothelium-journal of Endothelial Cell Research, 1
-
David Hood, D. Grosenbaugh, Mostafa Mostafa, Sherry Morgan, Barbara Thomas (1993)
The role of vascular mechanisms in the development of acute equine laminitis.Journal of veterinary internal medicine, 7 4
-
(1981)
Acute equine laminitis : renal morphology and endocrine interplay -
A. Leone, S. Moncada, Patrick Vallance, A. Calver, J. Collier (1992)
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failureThe Lancet, 339
-
Hinckley Hinckley, Keen Keen, Howard Howard, Henderson Henderson (1994)
The role of nitric oxide precursors and inhibitors in acute equine laminitisJ. Endocrinol., 143
-
J. Moore, D. Allen, E. Clark (1989)
Pathophysiology of acute laminitis.The Veterinary clinics of North America. Equine practice, 5 1
-
C. Templeton, G. Bottoms, J. Fessler, J. Turek, G. Boon (1985)
Effects of repeated endotoxin injections on prostanoids, hemodynamics, endothelial cells, and survival in ponies.Circulatory shock, 16 3
-
Hinckley Hinckley, Henderson Henderson (1995)
Plasma endothelins in normal and acutely laminitic horsesJ. Endocrinol., 147
-
Hunt Hunt (1991)
The pathophysiology of acute laminitisComp. cont. Educ. pract. vet., 13
-
Vallance Vallance, Leone Leone, Calver Calver, Collier Collier, Moncada Moncada (1992)
Accumulation of an inhibitor of nitric oxide synthesis in chronic renal failureLancet, 339
-
N. Robinson (1990)
Digital blood flow, arteriovenous anastomoses and laminitis.Equine veterinary journal, 22 6
-
M. Thorniley, Y. Wickramasinghe, P. Rolfe (1988)
Near infra-red spectroscopy: a new technique for the non-invasive monitoring of tissue and blood oxygenation in vivoBiochemical Society Transactions, 16
-
J. Coffman, J. Johnson, M. Guffy, E. Finocchio (1970)
Hoff circulation in equine laminitis.Journal of the American Veterinary Medical Association, 156 1
-
G. Baxter (1994)
Effects of tumor necrosis factor on in vitro digital arterial responses in horses.American journal of veterinary research, 55 4
-
C. Pollitt, G. Molyneux (1990)
A scanning electron microscopical study of the dermal microcirculation of the equine foot.Equine veterinary journal, 22 2
-
F. Galey, A. Twardock, T. Goetz, David Schaeffer, Jeffery Hall, Val Beasley (1990)
Gamma scintigraphic analysis of the distribution of perfusion of blood in the equine foot during black walnut (Juglans nigra)-induced laminitis.American journal of veterinary research, 51 4
-
Hood Hood (1979)
Current concepts of the physiopathology of laminitisProc. Am. Ass. equine Practnrs., 25
-
Baxter (1992)
Equine laminitisEquine Pract., 14
-
Griffith Tm (1994)
Modulation of blood flow and tissue perfusion by endothelium‐derived relaxing factorExperimental Physiology, 79
-
Douglas Weiss, Raymond Geor, G. Johnston, A. Trent (1994)
Microvascular thrombosis associated with onset of acute laminitis in ponies.American journal of veterinary research, 55 5
-
E. Roberts, Ricardo Ochoa, P. Haynes (1980)
Correlation of Dermal-Epidermal Laminar Lesions of Equine Hoof with Various Disease ConditionsVeterinary Pathology, 17
-
R. Palmer, A. Ferrige, S. Moncada (1987)
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factorNature, 327
-
E. Änggård (1990)
The endothelium--the body's largest endocrine gland?Journal of Endocrinology, 127
-
S. Moncada, R. Palmer, E. Higgs (1991)
Nitric oxide: physiology, pathophysiology, and pharmacology.Pharmacological reviews, 43 2
-
S. Baudouin, P. Bath, J. Martin, R. Bois, Timothy Evans (1993)
L-arginine infusion has no effect on systemic haemodynamics in normal volunteers, or systemic and pulmonary haemodynamics in patients with elevated pulmonary vascular resistance.British journal of clinical pharmacology, 36 1
-
G. Baxter, R. Laskey, R. Tackett, J. Moore, D. Allen (1989)
In vitro reactivity of digital arteries and veins to vasoconstrictive mediators in healthy horses and in horses with early laminitis.American journal of veterinary research, 50 4
-
M. Creager, Shelly Gallagher, X. Girerd, Sharon Coleman, V. Dzau, V. Dzau, John Cooke (1992)
L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans.The Journal of clinical investigation, 90 4
-
Neil Hampson, C. Piantadosi (1988)
Near infrared monitoring of human skeletal muscle oxygenation during forearm ischemia.Journal of applied physiology, 64 6
-
D. Rees, R. Palmer, S. Moncada (1989)
Role of endothelium-derived nitric oxide in the regulation of blood pressure.Proceedings of the National Academy of Sciences of the United States of America, 86 9
-
J. Fessler, G. Bottoms, O. Roesel, A. Moore, H. Frauenfelder, G. Boon (1982)
Endotoxin-induced change in hemograms, plasma enzymes, and blood chemical values in anesthetized ponies: effects of flunixin meglumine.American journal of veterinary research, 43 1
-
M. Essenpreis, M. Cope, C. Elwell, S. Arridge, P. Zee, D. Delpy (1993)
Wavelength dependence of the differential pathlength factor and the log slope in time-resolved tissue spectroscopy.Advances in experimental medicine and biology, 333
-
S. Katsuki, Arnold Wp, C. Mittal, F. Murad (1977)
Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.Journal of cyclic nucleotide research, 3 1
-
C. Lees, S. Campbell, E. Jauniaux, Richard Brown, B. Ramsay, D. Gibb, John Martin, S. Moncada (1994)
Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donorThe Lancet, 343
-
R. Furchgott, J. Zawadzki (1980)
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineNature, 288
-
Hood Hood, Amoss Amoss, Hightower Hightower, McDonald McDonald, McGrath McGrath, McMullan McMullan, Scritchfield Scritchfield (1978)
Equine laminitis 1. Radioisotopic analysis of the hemodynamics of the foot during the acute diseaseJ. equine Med. Surg., 2
-
G. Molyneux, C. Haller, K. Mogg, C. Pollitt (1994)
The structure, innervation and location of arteriovenous anastomoses in the equine foot.Equine veterinary journal, 26 4
- Publisher
- Wiley
- Copyright
- © 1996 EVJ Ltd
- ISSN
- 0425-1644
- eISSN
- 2042-3306
- DOI
- 10.1111/j.2042-3306.1996.tb01586.x
- Publisher site
- See Article on Publisher Site
Abstract
Summary The potential for participation of the arginine‐nitric oxide system in the aetiology of acute equine laminitis has been assessed. Nitric oxide (NO), produced by the action of NO synthase (NOS) on its substrate l‐arginine, relaxes vascular smooth muscle to cause vasodilatation. An attenuated normal vasodilatory tone may characterise the pathogenesis of acute equine laminitis. An intravenous infusion of 10%l‐arginine in 0.9% saline caused vasodilatation in the hoof of a normal pony and immediate reperfusion of laminal tissues in an acutely laminitic pony, detected noninvasively by near infrared spectroscopy (NIRS), but the amino acid had little effect on systemic blood pressure. Treatment of acute laminitis with glyceryl trinitrate applied topically to the pasterns reduced the typical ‘bounding pulses’ in treated limbs, reduced lameness and lowered systemic blood pressure. Nitric oxide is likely to participate in the multifactorial pathogenesis of equine laminitis.
Journal
Equine Veterinary Journal – Wiley
Published: Jan 1, 1996