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- Publisher
- Springer Journals
- Copyright
- Copyright © 1987 by Springer-Verlag
- Subject
- Biomedicine; Pharmacology/Toxicology; Psychiatry
- ISSN
- 0033-3158
- eISSN
- 1432-2072
- DOI
- 10.1007/BF02439600
- Publisher site
- See Article on Publisher Site
Abstract
213 93 93 1 1 M. B. Bowers Jr M. J. Bannon F. J. Hoffman Jr Departments of Psychiatry and Pharmacology, The Abraham Ribicoff Research Facilities, Connecticut Mental Health Center Yale University School of Medicine USA 25 Park Street 06519 New Haven CONN USA Abstract Phencyclidine combined with footshock stress produced a greater increase in the homovanillic acid content of prefrontal cortex than either phencyclidine or footshock alone. Phencyclidine decreased both substance P and substance K in the ventral tegmental area. The results suggest that phencyclidine and footshock activate forebrain dopaminergic systems in part by separate mechanisms.
Journal
Psychopharmacology – Springer Journals
Published: Sep 1, 1987