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References (4)
-
A. G. E. Pearse (1974)
The APUD cell concept and its implications in pathologyPathol. Ann., 9
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C. Toker (1972)
Trabecular carcinoma of the skin.Archives of dermatology, 105 1
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M. Mcgavran (1964)
"Chromaffin" Cell: Electron Microscopic Identification in the Human DermisScience, 145
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K. Hashimoto (1972)
The ultrastructure of the skin of human embryos. X. Merkel tactile cells in the finger and nail.Journal of anatomy, 111 Pt 1
- Publisher
- Wiley
- Copyright
- "Copyright © 1978 Wiley Subscription Services, Inc., A Wiley Company"
- ISSN
- 0008-543X
- eISSN
- 1097-0142
- DOI
- 10.1002/1097-0142(197811)42:5<2311::AID-CNCR2820420531>3.0.CO;2-L
- Publisher site
- See Article on Publisher Site
Abstract
We report the electron microscopic studies of three trabecular carcinomas of the skin. The presence of neurosecretory granules in all three tumors suggests that trabecular carcinoma originates from one of the neurocrest derivatives, most probably, Merkel cells. The ultrastructural findings confirm Toker's original concept that trabecular carcinomas comprise a distinct group of skin tumor. The recognition of these tumors would enable one to make such a diagnosis on frozen section, which, in turn, might provide an opportunity for more specific cytochemical and immunofluorescent characterization. Cancer 42:2311–2321, 1978.
Journal
Cancer – Wiley
Published: Nov 1, 1978