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Nucleoside diphosphate kinases catalyze the reversible transfer of the γ phosphate of nucleosidetriphosphates to nucleoside diphosphates. This minireview presents recent advances inunderstanding the reaction mechanism using steady-state and fast kinetic studies, X-raycrystallography, and site-directed mutagenesis. We also briefly discuss the physiological relevance ofin vitro studies.
Journal of Bioenergetics and Biomembranes – Springer Journals
Published: Oct 6, 2004
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