Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Linseman (1989)
Central vs. peripheral mediation of opioid effects on alcohol consumption in free-feeding ratsPharmacology Biochemistry and Behavior, 33
OP Pucilowski, DH Overstreet, AH Rezvani, DS Janowsky (1992)
Presented at the International Meeting on Strategies for Studying CNS Active Compounds: Models, Screens and Clinical SyndromesBehav Genet
W. Lynch (1986)
Opiate blockade inhibits saccharin intake and blocks normal preference acquisitionPharmacology Biochemistry and Behavior, 24
Heather Looy, H. Weingarten (1992)
Facial expressions and genetic sensitivity to 6-n-propylthiouracil predict hedonic response to sweetPhysiology & Behavior, 52
K Touzani, K Akarid, L Velley (1991)
Modulation of saccharin preference by morphine and naloxone: Inversion of drug effects as a function of saccharin concentrationBull Psychon Soc, 38
M. Pelchat, S. Danowski (1992)
A possible genetic association between PROP-tasting and alcoholismPhysiology & Behavior, 51
J. Sinclair, A. Kampov-Polevoy, R. Stewart, T. Li (1992)
Taste preferences in rat lines selected for low and high alcohol consumption.Alcohol, 9 2
BA Gosnell, MJ Majchrzak (1989)
Centrally administered opioid peptides stimulate saccharin intake in nondeprived ratsTrends Pharmacol Sci, 33
E. Sellers, G. Higgins, M. Sobell (1992)
5-HT and alcohol abuse.Trends in pharmacological sciences, 13 2
Thomas Tschopp, Marjorie Zucker (1972)
Hereditary defect in platelet function in rats.Blood, 40 2
H Looy, HP Weingarten (1992)
Facial expressions and genetic sensitivity to 6‐n‐propylthiouracil predict hedonic response to sweetPharmacol Biochem Behav, 52
JL Fuller, R Thompson (1960)
Behavioral GeneticsPhysiol Behav
A. Kampov-Polevoy, O. Kasheffskaya, J. Sinclair (1990)
Initial acceptance of ethanol: gustatory factors and patterns of alcohol drinking.Alcohol, 7 2
B. Gosnell, M. Majchrzak (1989)
Centrally administered opioid peptides stimulate saccharin intake in nondeprived ratsPharmacology Biochemistry and Behavior, 33
G Gora‐Maslak, GE McClearn, JD Crabbe (1991)
Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacologyRecent Dev Alcohol, 104
OP Pucilowski, AH Rezvani, DS Janowsky (1992)
Suppression of alcohol and saccharin preference in rats by a novel Ca+2 channel inhibitor, Goe 5438, 197
EM Sellers, GA Higgins, MB Sobell (1992)
5‐Hydroxytryptamine and alcohol abuseBrain Res Bull, 13
J. Belknap, J. Crabbe, R. Plomin, G. Mcclearn, K. Sampson, L. O'toole, G. Gora-Maslak (1992)
Single-locus control of saccharin intake in BXD/Ty recombinant inbred (RI) mice: Some methodological implications for RI strain analysisBehavior Genetics, 22
AH Rezvani, DH Overstreet, DS Janowsky (1991)
Drug‐induced reductions in ethanol intake in alcohol preferring and Fawn‐Hooded ratsAlcohol Alcohol Suppl, 1
B. Gosnell, D. Krahn (1992)
The relationship between saccharin and alcohol intake in rats.Alcohol, 9 3
K. Touzani, K. Akarid, L. Velley (1991)
Modulation of saccharin preference by morphine and naloxone: Inversion of drug effects as a function of saccharin concentrationPharmacology Biochemistry and Behavior, 38
D. Overstreet, A. Rezvani, D. Janowsky (1992)
Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholismBiological Psychiatry, 31
D. Blizard (1981)
The Maudsley reactive and nonreactive strains: A North American perspectiveBehavior Genetics, 11
K. Wild, S. Marglin, L. Reid (1988)
Small doses of morphine enhance voluntary intake of a solution of only ethanol and waterBulletin of the psychonomic society, 26
R. Wise, M. Bozarth (1984)
Brain reward circuitry: Four circuit elements “wired” in apparent seriesBrain Research Bulletin, 12
R. Swinson (1983)
Genetic markers and alcoholism.Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1
AB Kampov‐Polevoy, DH Overstreet, AH Rezvani
Behavioral patterns associated with alcohol consumption in different rat strainsAlcohol
W. Mcbride, James Murphy, L. Lumeng, Ting-kai Li (1990)
Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats.Alcohol, 7 3
RP Sivinson (1983)
Genetic markers and alcoholismPharmacol Biochem Behav, 1
N. Adams, Z. Shihabi, D. Blizard (1991)
Ethanol preference in the Harrington derivation of the Maudsley Reactive and Non-Reactive strains.Alcoholism, clinical and experimental research, 15 2
Saccharin and ethanol intakes were measured in seven strains of rats known to differ in their preferences for ethanol: The Fawn‐Hooded (FH), alcohol‐preferring (P) and Maudsley Reactive rats have been reported to drink ethanol voluntarily, whereas the alcohol‐nonpreferring, Maudsley Nonreactive and Flinders Line (FSL and FRL) rats do not. Saccharin and ethanol intakes were highly correlated (r =+0.61) over all strains, with the FH rats drinking the most of both solutions. Correlation coefficients between pairs of drinking versus nondrinking rat strains were even higher. In a second experiment, genetically heterogeneous F2 progeny from cross‐breeding the ethanol‐preferring FH rats with the ethanol‐nonpreferring Flinders Resistant Line (FRL) rats were studied. The results indicated a high positive correlation between saccharin and ethanol intakes (+0.65). These findings suggest that the association between saccharin and ethanol intakes previously reported in rat strains with different preferences for ethanol may have a similar genetic basis.
Alcoholism: Clinical & Experimental Research – Wiley
Published: Apr 1, 1993
Keywords: ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.