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- Publisher
- Annual Reviews
- Copyright
- Copyright © 1997 by Annual Reviews Inc. All rights reserved
- Subject
- Review Articles
- ISSN
- 1081-0706
- eISSN
- 1530-8995
- DOI
- 10.1146/annurev.cellbio.13.1.261
- pmid
- 9442875
- Publisher site
- See Article on Publisher Site
Abstract
▪ Abstract Cyclin-dependent kinases (Cdks) play a well-established role in the regulation of the eukaryotic cell division cycle and have also been implicated in the control of gene transcription and other processes. Cdk activity is governed by a complex network of regulatory subunits and phosphorylation events whose precise effects on Cdk conformation have been revealed by recent crystallographic studies. In the cell, these regulatory mechanisms generate an interlinked series of Cdk oscillators that trigger the events of cell division.
Journal
Annual Review of Cell and Developmental Biology – Annual Reviews
Published: Nov 1, 1997