Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. Nakashima, Y. Kido, Naoki Kobayashi, Y. Motoki, M. Neushul, Naoki Yamamoto (2004)
Antiretroviral activity in a marine red alga: reverse transcriptase inhibition by an aqueous extract of Schizymenia pacificaJournal of Cancer Research and Clinical Oncology, 113
L. Zeitlin, K. Whaley, T. Hegarty, T. Moench, R. Cone (1997)
Tests of vaginal microbicides in the mouse genital herpes model.Contraception, 56 5
J. Urones, M. Araújo, F. Palma, P. Basabe, I. Marcos, R. Moro, A. Lithgow, J. Pineda (1992)
Meroterpenes from Cystoseira usneoides IIPhytochemistry, 31
W. Gerwick, M. Bernart (1993)
Eicosanoids and Related Compounds from Marine Algae
A. Nugent (2003)
Lipid Biochemistry. An IntroductionNutrition Bulletin, 28
Luis Carcache, Jonierr Rodriguez, K. Rein (2003)
The structural basis for kainoid selectivity at AMPA receptors revealed by low-mode docking calculations.Bioorganic & medicinal chemistry, 11 4
Keisuke Watanabe, K. Umeda, Y. Kurita, C. Takayama, M. Miyakado (1990)
Two insecticidal monoterpenes, telfairine and aplysiaterpenoid A, from the red alga Plocamium telfairiae: Structure elucidation, biological activity, and molecular topographical consideration by a semiempirical molecular orbital study☆Pesticide Biochemistry and Physiology, 37
Pascale Patier, J. Yvin, B. Kloareg, Y. Liénart, C. Rochas (1993)
Seaweed liquid fertilizer fromAscophyllum nodosum contains elicitors of plantd-glycanasesJournal of Applied Phycology, 5
H. Kakita, T. Kitamura, A. Chapman, R. Anderson, V. Vreeland, I. Davison (2003)
Hemagglutinating activity in the cultivated red alga Gracilaria chorda Holmes from Japan.
T. Higa, M. Kuniyoshi (2000)
TOXINS ASSOCIATED WITH MEDICINAL AND EDIBLE SEAWEEDSJournal of Toxicology: Toxin Reviews, 19
A. Kawakubo, H. Makino, J. Ohnishi, H. Hirohara, K. Hori (1997)
The marine red alga Eucheuma serra J. Agardh, a high yielding source of two isolectinsJournal of Applied Phycology, 9
K. Jurd, D. Rogers, G. Blunden, D. Mclellan (1995)
Anticoagulant properties of sulphated polysaccharides and a proteoglycan from Codium fragile ssp. atlanticumJournal of Applied Phycology, 7
G. Majczak, R. Richartz, M. Duarte, M. Noseda, A. Chapman, R. Anderson, V. Vreeland, I. Davison (2003)
Antiherpetic activity of heterofucans isolated from Sargassum stenophyllum (Fucales, Phaeophyta).
K. Hori, K. Miyazawa, N. Fusetani, Kanehisa Hashimoto, Keiji Ito (1986)
Hypnins, low-molecular weight peptidic agglutinins isolated from a marine red alga Hypnea japonicaBiochimica et Biophysica Acta, 873
M. Witvrouw, J. Esté, M. Mateu, D. Reymen, G. Andrei, R. Snoeck, S. Ikeda, R. Pauwels, N. Bianchini, J. Desmyter, E. Clercq (1994)
Activity of a Sulfated Polysaccharide Extracted from the Red Seaweed Aghardhiella Tenera against Human Immunodeficiency Virus and Other Enveloped VirusesAntiviral Chemistry and Chemotherapy, 5
(1906)
Inhibitory ActionBotanical Gazette, 41
Y. Fukuyama, M. Kodama, I. Miura, Zyunei Kinzyo, M. Kido, Hideo Mori, Y. Nakayama, Masayuki Takahashi (1989)
Structure of an anti-plasmin inhibitor, eckol, isolated from the brown alga Ecklonia kurome Okamura and inhibitory activities of its derivatives on plasma plasmin inhibitors.Chemical & pharmaceutical bulletin, 37 2
Nicholas Osborne, Penny Webb, Glendon Shaw (2001)
The toxins of Lyngbya majuscula and their human and ecological health effects.Environment international, 27 5
G. Cordell (2000)
Biodiversity and drug discovery--a symbiotic relationship.Phytochemistry, 55 6
S. Feldman, S. Reynaldi, C. Stortz, A. Cerezo, E. Damonte (1999)
Antiviral properties of fucoidan fractions from Leathesia difformis.Phytomedicine : international journal of phytotherapy and phytopharmacology, 6 5
A. Mayer, Virginia Lehmann (2000)
Marine pharmacology in 1998: Marine compounds with antibacterial, anticoagulant, antifungal, antiinflammatory, anthelmintic, antiplatelet, antiprotozoal, and antiviral activities; with actions on the cardiovascular, endocrine, immune, and nervous systems; and other miscellaneous mechanisms of actionThe Pharmacologist
P. Carthew (2002)
Safety of carrageenan in foods.Environmental Health Perspectives, 110
Minoru Satô, T. Nakano, M. Takeuchi, N. Kanno, E. Nagahisa, Yoshikazu Sato (1996)
Distribution of neuroexcitatory amino acids in marine algaePhytochemistry, 42
D. Graber, K. Meier (1991)
Acute misoprostol toxicity.Annals of emergency medicine, 20 5
M. Baba, R. Snoeck, R. Pauwels, E. Clercq (1988)
Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virusAntimicrobial Agents and Chemotherapy, 32
G. Dannhardt, W. Kiefer (2001)
Cyclooxygenase inhibitors--current status and future prospects.European journal of medicinal chemistry, 36 2
K. Saito, M. Nishijima, N. Ohno, T. Yadomae, T. Miyazaki (1992)
Structure and antitumor activity of the less-branched derivatives of an alkali-soluble glucan isolated from Omphalia lapidescens. (Studies on fungal polysaccharide. XXXVIII).Chemical & pharmaceutical bulletin, 40 1
P. Religa, M. Kazi, J. Thyberg, Z. Gaciong, J. Swedenborg, U. Hedin (2000)
Fucoidan inhibits smooth muscle cell proliferation and reduces mitogen-activated protein kinase activity.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 20 5
T. Kuznetsova, N. Krylova, N. Besednova, V. Vasil'eva, T. Zviagintseva, S. Krashevskiĭ, L. Eliakova (1994)
[The effect of translam on the natural resistance indices of the irradiated organism].Radiatsionnaia biologiia, radioecologiia, 34 2
前田 満, 児玉 亨, 田中 隆治, 吉栖 肇, 竹本 常松, 野本 享資, 藤田 稔夫 (1986)
STRUCTURES OF ISODOMOIC ACIDS A, B AND C, NOVEL INSECTICIDAL AMINO ACIDS FROM THE RED ALGA CHONDRIA ARMATAChemical & Pharmaceutical Bulletin, 34
K. Nomura, H. Nakamura, N. Suzuki (2000)
False fertilization in sea urchin eggs induced by diabolin, a 120K kelp protein.Biochemical and biophysical research communications, 272 3
G. Culioli, M. Daoudi, A. Ortalo-Magné, R. Valls, L. Piovetti (2001)
(S)-12-hydroxygeranylgeraniol-derived diterpenes from the brown alga Bifurcaria bifurcata.Phytochemistry, 57 4
Lubna Zaman, Osamu Arakawa, A. Shimosu, Y. Onoue, S. Nishio, Yasuo Shida, Tamao Noguchi (1997)
Two new isomers of domoic acid from a red alga, Chondria armata.Toxicon : official journal of the International Society on Toxinology, 35 2
Chertkov Ks, Davydova Sa, Nesterova Ta, Zviagintseva Tn, Eliakova La (1999)
Efficiency of polysaccharide translam for early treatment of acute radiation illnessRadiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk, 39
F. Trento, Franco Cattaneo, R. Pescador, R. Porta, Laura Ferro (2001)
Antithrombin activity of an algal polysaccharide.Thrombosis research, 102 5
A. Kolender, M. Matulewicz, A. Cerezo (1995)
Structural analysis of antiviral sulfated α-d-(1 → 3)-linked mannansCarbohydrate Research, 273
David Schaeffer, Victor Krylov (2000)
Anti-HIV activity of extracts and compounds from algae and cyanobacteria.Ecotoxicology and environmental safety, 45 3
R. Kazlauskas, J. Mulder, P. Murphy, R. Wells (1981)
New metabolites from the brown alga Caulocystis cephalornithosAustralian Journal of Chemistry, 33
M. Noa, R. Más, D. Carbajal, S. Valdés (2000)
Effect of D-002 on acetic acid-induced colitis in rats at single and repeated doses.Pharmacological research, 41 4
G. Premakumara, W. Ratnasooriya, L. Tillekeratne (1995)
Studies on the post-coital contraceptive mechanisms of crude extract of Sri Lankan marine red algae, Gelidiella acerosa.Contraception, 52 3
G. Bond, Art Zee (1994)
Overdosage of misoprostol in pregnancy.American journal of obstetrics and gynecology, 171 2
E. Nishide, H. Anzai, N. Uchida (1993)
Effects of alginates on the ingestion and excretion of cholesterol in the ratJournal of Applied Phycology, 5
E. Clercq (1996)
Chemotherapy of human immunodeficiency virus (HIV) infection: anti-HIV agents targeted at early stages in the virus replicative cycle.Biomedicine & Pharmacotherapy, 50
D. Rogers, Kanji Hori (1993)
Marine algal lectins: new developmentsHydrobiologia, 260-261
A. Barcelo, J. Claustre, F. Moro, J. Chayvialle, Cuber Jc, P. Plaisancié (2000)
Mucin secretion is modulated by luminal factors in the isolated vascularly perfused rat colonGut, 46
G. Premakumara, W. Ratnasooriya, L. Tillekeratne (1996)
Isolation of a non-steroidal contragestative agent from Sri Lankan marine red alga, Gelidiella acerosa.Contraception, 54 6
M. Hamann, P. Scheuer (1993)
Kahalalide F: a bioactive depsipeptide from the sacoglossan mollusk Elysia rufescens and the green alga Bryopsis spJournal of the American Chemical Society, 115
H. Tanabe, H. Kamishima, Yoshinari Kobayashi (1993)
Inhibitory effect of red alga lectin and skipjack fat on the growth of the red tide plankton Chattonella antiquaJournal of Fermentation and Bioengineering, 75
B. Haefner (2003)
Drugs from the deep: marine natural products as drug candidates.Drug discovery today, 8 12
K. Stefanov, M. Konaklieva, E. Brechany, W. Christie (1988)
Fatty acid composition of some algae from the Black SeaPhytochemistry, 27
Jeong Na, Ka Lee, Joobeom Seo, Jae Kim (2005)
Serendipitous one-pot synthesis of brand-new, bowl-shaped molecular architecture from phloroglucinol and ninhydrinTetrahedron Letters, 46
Y. Fukuyama, M. Kodama, I. Miura, Ziunei Kinzyo, Hideo Mori, Y. Nakayama, Masayuki Takahashi (1990)
Anti-plasmin inhibitor. VI. Structure of phlorofucofuroeckol A, a novel phlorotannin with both dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome Okamura.Chemical & pharmaceutical bulletin, 38 1
J. White, P. Blakemore, C. Browder, J. Hong, C. Lincoln, P. Nagornyy, L. Robarge, D. Wardrop (2001)
Total synthesis of the marine toxin polycavernoside A via selective macrolactonization of a trihydroxy carboxylic acid.Journal of the American Chemical Society, 123 35
D. Smith, D. Kitts (1994)
A competitive enzyme-linked immunoassay for domoic acid determination in human body fluids.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 32 12
J. Tobacman (2001)
Review of harmful gastrointestinal effects of carrageenan in animal experiments.Environmental Health Perspectives, 109
S Abe, T Kaneda (1975)
Studies on the effects of marine products on cholesterol metabolism in ratsBull. Japan Soc. Fish, 41
P. Kris-Etherton, K. Hecker, A. Bonanome, S. Coval, A. Binkoski, Kirsten Hilpert, A. Griel, T. Etherton (2002)
Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer.The American journal of medicine, 113 Suppl 9B
G. Impellizzeri, S. Mangiafico, G. Oriente, M. Piattelli, S. Sciuto, E. Fattorusso, S. Magno, C. Santacroce, D. Sica (1975)
Amino acids and low-molecular-weight carbohydrates of some marine red algaePhytochemistry, 14
F. Church, J. Meade, R. Treanor, H. Whinna (1989)
Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin.The Journal of biological chemistry, 264 6
H. Fujiki, M. Suganuma (1996)
Naturally-Derived Tumor Promoters and Inhibitors of CarcinogenesisJournal of Toxicology-toxin Reviews, 15
S. Bates (2000)
DOMOIC‐ACID‐PRODUCING DIATOMS: ANOTHER GENUS ADDED!Journal of Phycology, 36
K. Matsubara, Y. Matsuura, K. Hori, K. Miyazawa (2000)
An anticoagulant proteoglycan from the marine green alga, Codium pugniformisJournal of Applied Phycology, 12
(2000)
Cytotoxic and antiviral compound
R. Malhotra, M. Ward, H. Bright, R. Priest, M. Foster, M. Hurle, E. Blair, M. Bird (2003)
Isolation and characterisation of potential respiratory syncytial virus receptor(s) on epithelial cells.Microbes and infection, 5 2
Y. Angulo, B. Lomonte (2003)
Inhibitory effect of fucoidan on the activities of crotaline snake venom myotoxic phospholipases A(2).Biochemical pharmacology, 66 10
M. Shanmugam, K. Mody, B. Ramavat, A. Murthy, A. Siddhanta (2002)
Screening of codiacean algae (Chlorophyta) of the Indian coasts for blood anticoagulant activityIndian Journal of Marine Sciences, 31
M. Govenkar, S. Wahidulla (2000)
Constituents of Chondria armata.Phytochemistry, 54 8
H. Lima, F. Costa, A. Sampaio, S. Neves, N. Benevides, D. Teixeira, D. Rogers, A. Freitas (1998)
Induction and inhibition of human lymphocyte transformation by the lectin from the red marine alga Amansia multifidaJournal of Applied Phycology, 10
E. Nishide, N. Uchida, A. Chapman, R. Anderson, V. Vreeland, I. Davison (2003)
Effects of Ulva powder on the ingestion and excretion of cholesterol in rats.
Y. Kato, P. Scheuer (1974)
Aplysiatoxin and debromoaplysiatoxin, constituents of the marine mollusk Stylocheilus longicauda (Quoy and Gaimard, 1824).Journal of the American Chemical Society, 96 7
H. Nagai, T. Yasumoto, Y. Hokama (1997)
Manauealides, some of the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii.Journal of natural products, 60 9
FC Church, JB Meade, RE Treanor, HC Whinna (1989)
Antithrom-bin activity of fucoidan.J. biol. Chem., 264
Mami Takikawa, Kiyoko Uno, T. Ooi, T. Kusumi, S. Akera, Morimitsu Muramatsu, H. Mega, C. Horita (1998)
Crenulacetal C, a Marine Diterpene, and Its Synthetic Mimics Inhibiting Polydora websterii, a Harmful Lugworm Damaging Pearl CultivationChemical & Pharmaceutical Bulletin, 46
B. Featonby-Smith, J. Staden (1984)
Identification and Seasonal Variation of Endogenous Cytokinins in Ecklonia maxima (Osbeck) Papenf., 27
N. Ponce, C. Pujol, E. Damonte, M. Flores, C. Stortz (2003)
Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies.Carbohydrate research, 338 2
Blumenthal Pd (1988)
Prospective comparison of Dilapan and laminaria for pretreatment of the cervix in second-trimester induction abortion.Obstetrics & Gynecology, 72
WC Boyd, RM Reguera (1949)
Hemagglutinating substances in var-ious plantsJ. Immunol., 62
C. Francisco, B. Banaigs, R. Valls, L. Codomier (1985)
Mediterraneol a, a novel rearranged diterpenoid-hydroquinone from the marine alga cystoseira mediterraneaTetrahedron Letters, 26
M. Yotsu-Yamashita, Tetsuya Seki, V. Paul, H. Naoki, T. Yasumoto (1995)
Four new analogs of polycavernoside ATetrahedron Letters, 36
J. Al-Hassan, M. Ali,, M. Thomson, T. Fatima, C. Gubler, R. Criddle (1987)
Prostaglandin associated mortality following intravenous injection of catfish epidermal secretions in rabbits.Prostaglandins, leukotrienes, and medicine, 28 1
H. Ueyama, I. Sasaki, K. Shimomura, M. Suganuma (2005)
Specific protein interacting with a tumor promoter, debromoaplysiatoxin, in bovine serum is α1-acid glycoproteinJournal of Cancer Research and Clinical Oncology, 121
L. Panlasigui, Olivia Baello, Jeniffer Dimatangal, Benelyn Dumelod (2003)
Blood cholesterol and lipid-lowering effects of carrageenan on human volunteers.Asia Pacific journal of clinical nutrition, 12 2
I. Galgani, D. Pesando, J. Porthé‐Nibelle, B. Fossat, J. Girard (1996)
Effect of caulerpenyne, a toxin extracted from Caulerpa taxifolia on mechanisms regulating intracellular pH in sea urchin eggs and sea bream hepatocytes.Journal of biochemical toxicology, 11 5
D. Pesando, P. Huitorel, V. Dolcini, P. Amade, J. Girard (1998)
Caulerpenyne interferes with microtubule-dependent events during the first mitotic cycle of sea urchin eggs.European journal of cell biology, 77 1
S. Mazumder, P. Ghosal, C. Pujol, M. Carlucci, E. Damonte, B. Ray (2002)
Isolation, chemical investigation and antiviral activity of polysaccharides from Gracilaria corticata (Gracilariaceae, Rhodophyta).International journal of biological macromolecules, 31 1-3
M. Pedrotti, R. Lémée (1999)
Effect of microalgae treated with natural toxins on the nutrition and development of filter-feeding sea-urchin larvaeMarine Environmental Research, 48
S. Bates (1998)
Ecophysiology and Metabolism of ASP Toxin Production
M. Carlucci, C. Pujol, M. Ciancia, M. Noseda, M. Matulewicz, E. Damonte, A. Cerezo (1997)
Antiherpetic and anticoagulant properties of carrageenans from the red seaweed Gigartina skottsbergii and their cyclized derivatives: correlation between structure and biological activity.International journal of biological macromolecules, 20 2
B. Nuijen, B. Nuijen, M. Bouma, H. Talsma, C. Manada, J. Jimeno, L. López-Lázaro, A. Bult, J. Beijnen (2001)
Development of a Lyophilized Parenteral Pharmaceutical Formulation of the Investigational Polypeptide Marine Anticancer Agent Kahalalide FDrug Development and Industrial Pharmacy, 27
Manish PatankarS, Sergio OehningerQ, Townsend Barnett, Roy Williams, Gary Clark (1993)
A revised structure for fucoidan may explain some of its biological activities.The Journal of biological chemistry, 268 29
L. Barriault, S. Boulet, K. Fujiwara, A. Murai*, L. Paquette, M. Yotsu-Yamashita (1999)
Synthesis and biological evaluation of analogs of the marine toxin polycavernoside A.Bioorganic & medicinal chemistry letters, 9 14
M. Maeda, T. Kodama, M. Saito, Takaharu Tanaka, H. Yoshizumi, K. Nomoto, T. Fujita (1987)
Neuromuscular action of insecticidal domoic acid on the American cockroachPesticide Biochemistry and Physiology, 28
K. Sayed, P. Bartyzel, Xiaoyu Shen, Tony Perry, J. Zjawiony, M. Hamann (2000)
Marine Natural Products as Antituberculosis AgentsTetrahedron, 56
E. Damonte, J. Neyts, C. Pujol, R. Snoeck, G. Andrei, S. Ikeda, M. Witvrouw, D. Reymen, H. Haines, M. Matulewicz, A. Cerezo, C. Coto, E. Clerco (1994)
Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata.Biochemical pharmacology, 47 12
H. Maruyama, J. Nakajima, I. Yamamoto (1987)
A study on the anticoagulant and fibrinolytic activities of a crude fucoidan from the edible brown seaweed Laminaria religiosa, with special reference to its inhibitory effect on the growth of sarcoma-180 ascites cells subcutaneously implanted into mice.The Kitasato archives of experimental medicine, 60 3
Bertrand Kaeffer, C. Benard, Marc Lahaye, H. Blottière, C. Cherbut (1999)
Biological properties of ulvan, a new source of green seaweed sulfated polysaccharides, on cultured normal and cancerous colonic epithelial cells.Planta medica, 65 6
U. Ramsey, C. Bird, P. Shacklock, M. Laycock, J. Wright (1994)
Kainic acid and 1'-hydroxykainic acid from Palmariales.Natural toxins, 2 5
Takashi Nishino, T. Nagumo (1992)
Anticoagulant and antithrombin activities of oversulfated fucans.Carbohydrate research, 229 2
E. Ito, H. Nagai (1998)
Morphological observations of diarrhea in mice caused by aplysiatoxin, the causative agent of the red alga Gracilaria coronopifolia poisoning in Hawaii.Toxicon : official journal of the International Society on Toxinology, 36 12
D. Renn (1997)
Biotechnology and the red seaweed polysaccharide industry: status, needs and prospectsTrends in Biotechnology, 15
J. Sajiki, H. Kakimi (1998)
Identification of eicosanoids in the red algae, Gracilaria asiatica, using high-performance liquid chromatography and electrospray ionization mass spectrometry.Journal of chromatography. A, 795 2
G. Goetz, Y. Nakao, P. Scheuer (1997)
Two acyclic kahalalides from the sacoglossan mollusk Elysia rufescensJournal of Natural Products, 60
F. Pieta, M. Breschi, R. Scatizzi, F. Cinelli (1995)
Relaxing Activity of Two Linear Diterpenes from Cystoseira brachycarpa var. balearica on the Contractions of Intestinal PreparationsPlanta Medica, 61
I. Sugawara, W. Itoh, S. Kimura, S. Mori, K. Shimada (1989)
Further characterization of sulfated homopolysaccharides as anti-HIV agentsExperientia, 45
H. Kakita, S. Fukuoka, H. Obika, Z. Li, H. Kamishima (1997)
Purification and Properties of a High Molecular Weight Hemagglutinin from the Red Alga, Gracilaria verrucosa, 40
D. Davyt, Walter Entz, R. Fernández, R. Mariezcurrena, Á. Mombrú, J. Saldaña, L. Domínguez, J. Coll, E. Manta (1998)
A new indole derivative from the red alga Chondria atropurpurea. Isolation, structure determination, and anthelmintic activity.Journal of natural products, 61 12
N. Fusetani, K. Hashimoto (1984)
Prostaglandin E2: A candidate for causative agent of "ogonori" poisoning.Nippon Suisan Gakkaishi, 50
Benelyn Dumelod, Rachel Ramirez, Cecile Tiangson, E. Barrios, L. Panlasigui (1999)
Carbohydrate availability of arroz caldo with lambda-carrageenan.International journal of food sciences and nutrition, 50 4
J. Sajiki (1997)
Effects of Acetic Acid Treatment on the Concentrations of Arachidonic Acid and Prostaglandin E2 in the Red Algae, Gracilaria asiatica and G. rhodocaudataFisheries Science, 63
S. Abe, T. Kaneda (1975)
Studies on the effect of marine products on cholesterol metabolism in rats. XI. Isolation of a new betaine, ulvaline, from a green laver monosrtoma nitidum and its depressing effect on plasma cholesterol levels.Nippon Suisan Gakkaishi, 41
(1993)
Marine proteins and clinical chemistry
J. Mynderse, R. Moore (1978)
Toxins from blue-green algae: structures of oscillatoxin A and three related bromine-containing toxinsJournal of Organic Chemistry, 43
R. Sparidans, E. Stokvis, J. Jimeno, L. López-Lázaro, J. Schellens, J. Beijnen (2001)
Chemical and enzymatic stability of a cyclic depsipeptide, the novel, marine-derived, anti-cancer agent kahalalide FAnti-Cancer Drugs, 12
L Barriault, SL Boulet, K Fujiwara, A Murai, LA Paquette (1999)
Synthesis and biological evaluation of analogs of the marine toxin polycavernosideA. Bioorg. Med. Chem. Lett., 9
E. Stokvis, H. Rosing, Luis Lopez-Lazaro, I. Rodríguez, J. Jimeno, J. Supko, J. Schellens, J. Schellens, J. Beijnen, J. Beijnen (2002)
Quantitative analysis of the novel depsipeptide anticancer drug Kahalalide F in human plasma by high-performance liquid chromatography under basic conditions coupled to electrospray ionization tandem mass spectrometry.Journal of mass spectrometry : JMS, 37 9
A. Imbs, Anna Vologodskaya, N. Nevshupova, S. Khotimchenko, Edouard Titlyanov (2001)
Response of prostaglandin content in the red alga Gracilaria verrucosa to season and solar irradiance.Phytochemistry, 58 7
H Chen, P Sun, Q Song (1995)
Lectins, a powerful defensive weapon of aquatic animalsJ. Oceanogr. Huanghai Bohai Seas, 13
D. Parent-Massin, V. Fournier, P. Amade, R. Lémée, M. Durand-Clément, C. Delescluse, D. Pesando (1996)
Evaluation of the toxicological risk to humans of caulerpenyne using human hematopoietic progenitors, melanocytes, and keratinocytes in culture.Journal of toxicology and environmental health, 47 1
V. Grauffel, B. Kloareg, S. Mabeau, P. Durand, J. Jozefonvicz (1989)
New natural polysaccharides with potent antithrombic activity: fucans from brown algae.Biomaterials, 10 6
William Boyd, Rose Reguera (1949)
Hemagglutinating substances for human cells in various plants.Journal of immunology, 62 3
P. Buckle, B. Baldo, K. Taylor (1980)
The anti-inflammatory activity of marine natural products-6-n-tridecylsalicylic acid, flexibilide and dendalone 3-hydroxybutyrateAgents and Actions, 10
Y. Kan, T. Fujita, H. Nagai, B. Sakamoto, Y. Hokama (1998)
Malyngamides M and N from the Hawaiian Red Alga Gracilaria coronopifoliaJournal of natural products, 61 1
H. Okamura, S. Kuroda, K. Tomita, S. Ikegami, Y. Sugimoto, S. Sakaguchi, T. Katsuki*, M. Yamaguchi (1991)
Synthesis of aplysiatoxin: stereoselective synthesis of key fragmentsTetrahedron Letters, 32
Roderick Flower, Blackwell Gj (1976)
The importance of phospholipase-A2 in prostaglandin biosynthesis.Biochemical pharmacology, 25 3
M. Carlucci, L. Scolaro, E. Damonte (1999)
Inhibitory Action of Natural Carrageenans on Herpes simplex Virus Infection of Mouse AstrocytesChemotherapy, 45
H. Hennings, D. Lowry, V. Robinson, D. Morgan, H. Fujiki, S. Yuspa (1992)
Activity of diverse tumor promoters in a keratinocyte co-culture model of initiated epidermis.Carcinogenesis, 13 11
R. Patchett, A. Kelly, R. Kroll (1991)
The adsorption of bacteria to immobilized lectins.The Journal of applied bacteriology, 71 3
R. Gregson, J. Marwood, R. Quinn (1979)
The occurrence of prostaglandins PGE2 and PGF2α in a plant - the red alga .Tetrahedron Letters, 20
R. Dalmo, R. Seljelid (1995)
The immunomodulatory effect of LPS, laminaran and sulphated laminaran [β(l,3)-D-glucan] on Atlantic salmon, Salmo salar L., macrophages in vitroJournal of Fish Diseases, 18
J. Cisar, A. Sandberg, C. Abeygunawardana, G. Reddy, C. Bush (1995)
Lectin recognition of host-like saccharide motifs in streptococcal cell wall polysaccharides.Glycobiology, 5 7
Tamao Noguchi, Takashi Matsui, Keisuke Miyazawa, M. Asakawa, Noriaki Iijima, Yasuo Shida, Masahiro Fuse, Yasuo Hosaka, Chuji Kirigaya, Kenjirou Watabe, Susumu Usui, Atsuko Fukagawa (1994)
Poisoning by the red alga 'ogonori' (Gracilaria verrucosa) on the Nojima Coast, Yokohama, Kanagawa Prefecture, Japan.Toxicon : official journal of the International Society on Toxinology, 32 12
D. Coombe, C. Parish, I. Ramshaw, J. Snowden (1987)
Analysis of the inhibition of tumour metastasis by sulphated polysaccharidesInternational Journal of Cancer, 39
M. Yotsu-Yamashita, R. Haddock, T. Yasumoto (1993)
Polycavernoside A: A Novel Glycosidic Macrolide from the Red Alga Polycavernosa tsudai (Gracilaria edulis).ChemInform, 24
N. Benevides, M. Holanda, F. Melo, A. Freitas, A. Sampaio (1998)
Purification and Partial Characterisation of the Lectin from the Marine Red Alga Enantiocladia duperreyi (C. Agardh) Falkenberg, 41
E. Clercq (2000)
Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infectionMedicinal Research Reviews, 20
Chris Ireland, B. Copp, Mark Foster, Leonard McDonald, D. Radisky, J. Swersey (1993)
Biomedical Potential of Marine Natural Products
V. Chapman (1981)
Seaweeds and their uses
Fischel Jl, R. Lémée, P. Formento, C. Caldani, Mollura Jl, D. Pesando, A. Meinesz, P. Grelier, P. Pietra, A. Guerriero (1995)
Cell growth inhibitory effects of caulerpenyne, a sesquiterpenoid from the marine algae Caulerpa taxifolia.Anticancer research, 15 5B
M. Lamela, J. Anca, R. Villar, J. Otero, J. Calleja (1989)
Hypoglycemic activity of several seaweed extracts.Journal of ethnopharmacology, 27 1-2
M. Manefield, L. Harris, S. Rice, R. Nys, S. Kjelleberg (2000)
Inhibition of Luminescence and Virulence in the Black Tiger Prawn (Penaeus monodon) Pathogen Vibrio harveyi by Intercellular Signal AntagonistsApplied and Environmental Microbiology, 66
H. Okamura, S. Kuroda, S. Ikegami, K. Tomita, Y. Sugimoto, S. Sakaguchi, Yoshio Ito, T. Katsuki*, M. Yamaguchi (1993)
A formal synthesis of aplysiatoxin: enantioselective synthesis of kishi's aldehydeTetrahedron, 49
Tomoki Ohta, S. Sasaki, T. Oohori, S. Yoshikawa, H. Kurihara (2002)
Alpha-glucosidase inhibitory activity of a 70% methanol extract from ezoishige (Pelvetia babingtonii de Toni) and its effect on the elevation of blood glucose level in rats.Bioscience, biotechnology, and biochemistry, 66 7
D. Pesando, R. Lémée, C. Ferrua, P. Amade, J. Girard (1996)
Effects of caulerpenyne, the major toxin from Caulerpa taxifolia on mechanisms related to sea urchin egg cleavageAquatic Toxicology, 35
R. Valls, L. Piovetti, B. Banaigs, A. Archavlis, M. Pellegrini (1995)
(S)-13-hydroxygeranylgeraniol-derived furanoditerpenes from Bifurcaria bifurcata.Phytochemistry, 39 1
Jian Chen, W. Gerwick, R. Schatzman, M. Laney (1994)
Isorawsonol and related IMP dehydrogenase inhibitors from the tropical green alga Avrainvillea rawsonii.Journal of natural products, 57 7
T. Wakamiya, H. Nakamoto, T. Shiba (1984)
Structural determination of carnosadine, a new cyclopropyl amino acid, from red alga Grateloupia carnosaTetrahedron Letters, 25
A. Kelecom (2002)
Secondary metabolites from marine microorganisms.Anais da Academia Brasileira de Ciencias, 74 1
M. Maeda, T. Kodama, Takaharu Tanaka, Y. Ohfune, K. Nomoto, K. Nishimura, T. Fujita (1984)
Insecticidal and Neuromuscular Activities of Domoic Acid and Its Related CompoundsJournal of Pesticide Science, 9
Lee Cn, Chen Wf, Lai Hl, Shyu Mk, Chen Tm, Wu Rt, Shih Jc, Hsieh Fj (1998)
Comparison between Intravenous Prostaglandin E2 and Extraamniotic Prostaglandin F2alpha Instillation for Termination in Second-Trimester Pregnancy., 8
M. Manefield, M. Welch, M. Givskov, G. Salmond, S. Kjelleberg (2001)
Halogenated furanones from the red alga, Delisea pulchra, inhibit carbapenem antibiotic synthesis and exoenzyme virulence factor production in the phytopathogen Erwinia carotovora.FEMS microbiology letters, 205 1
M. Entzeroth, A. Blackman, J. Mynderse, R. Moore (1985)
Structures and stereochemistries of oscillatoxin B, 31-noroscillatoxin B, oscillatoxin D, and 30-methyloscillatoxin DJournal of Organic Chemistry, 50
H. Fujiki, M. Suganuma, S. Yoshizawa, S. Nishiwaki, B. Winyar, T. Sugimura (1991)
Mechanisms of action of okadaic acid class tumor promoters on mouse skin.Environmental Health Perspectives, 93
F. Pieta, A. Bilia, M. Breschi, F. Cinelli, I. Morelli, R. Scatizzi (1993)
Crude Extracts and Two Linear Diterpenes from Cystoseira balearica and their ActivityPlanta Medica, 59
D. Davyt, R. Fernández, L. Suescun, Á. Mombrú, J. Saldaña, L. Domínguez, J. Coll, M. Fujii, E. Manta (2001)
New sesquiterpene derivatives from the red alga Laurencia scoparia. Isolation, structure determination, and anthelmintic activity.Journal of natural products, 64 12
(2001)
Surface warfare in the sea
M. Hamann, C. Otto, P. Scheuer, D. Dunbar (1997)
Kahalalides: Bioactive Peptides from a Marine Mollusk Elysia rufescens and Its Algal Diet Bryopsis sp.ChemInform, 28
S. Abe, T. Kaneda (1973)
Studies on the Effect of Marine Products on Cholesterol Metabolism in Rats-VIIINippon Suisan Gakkaishi, 39
(1991)
Anticoaggulant properties of a fucoidan
(1972)
The effect of algal polysaccharides on depressing of plasma cholesterol level in rats
Da-lin Ren, H. Noda, H. Amano, K. Nisizawa (1994)
Antihypertensive and Antihyperlipidemic Effects of FunoranFisheries Science, 60
H. Nagai, T. Yasumoto, Y. Hokama (1996)
Aplysiatoxin and debromoaplysiatoxin as the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii.Toxicon : official journal of the International Society on Toxinology, 34 7
H. Shibata, I. Kimura-Takagi, M. Nagaoka, S. Hashimoto, R. Aiyama, M. Iha, S. Ueyama, T. Yokokura (2000)
Properties of fucoidan from Cladosiphon okamuranus tokida in gastric mucosal protectionBioFactors, 11
S. Oehninger, G. Clark, A. Acosta, G. Hodgen (1991)
Nature of the inhibitory effect of complex saccharide moieties on the tight binding of human spermatozoa to the human zona pellucida.Fertility and sterility, 55 1
L. Levine (1998)
Proteolysis negatively regulates agonist-stimulated arachidonic acid metabolism.Cellular signalling, 10 9
S. Matou, D. Helley, D. Chabut, A. Bros, A. Fischer (2002)
Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro.Thrombosis research, 106 4-5
K. Hopkins, G. Wang, L. Schmued (2000)
Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrainBrain Research, 864
John Wallace (1999)
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).The American journal of medicine, 107 6A
Hiroyuki Nakamura, M. Moriya (1999)
Purification and Partial Characterization of a Lectin-like Protein from the Sea Algae Laminaria diabolica that Induces Fertilization Envelope Formation in Sea Urchin Eggs, 16
L. Davies, D. Jamieson, J. Baird-Lambert, R. Kazlauskas (1984)
Halogenated pyrrolopyrimidine analogues of adenosine from marine organisms: pharmacological activities and potent inhibition of adenosine kinase.Biochemical pharmacology, 33 3
R. Moore (1982)
Toxins, anticancer agents, and tumor promoters from marine prokaryotesPure and Applied Chemistry, 54
H. Nakashima, Y. Kido, N. Kobayashi, Y. Motoki, M. Neushul, Naoki Yamamoto (1987)
Purification and characterization of an avian myeloblastosis and human immunodeficiency virus reverse transcriptase inhibitor, sulfated polysaccharides extracted from sea algaeAntimicrobial Agents and Chemotherapy, 31
P. Barbier, S. Guise, P. Huitorel, P. Amade, D. Pesando, C. Briand, V. Peyrot (2001)
Caulerpenyne from Caulerpa taxifolia has an antiproliferative activity on tumor cell line SK-N-SH and modifies the microtubule network.Life sciences, 70 4
T. Nishino, T. Nagumo (1991)
The sulfate-content dependence of the anticoagulant activity of a fucan sulfate from the brown seaweed Ecklonia kurome.Carbohydrate research, 214 1
Nozomu Bitou, M. Ninomiya, T. Tsujita, H. Okuda (1999)
Screening of lipase inhibitors from marine algaeLipids, 34
J. Llovo, A. Lopez, J. Fábregas, A. Muñoz (1993)
Interaction of lectins with Cryptosporidium parvum.The Journal of infectious diseases, 167 6
Mark Hamann, C. Otto, P. Scheuer, D. Dunbar (1996)
Kahalalides: Bioactive Peptides from a Marine Mollusk Elysia rufescens and Its Algal Diet Bryopsis sp.(1).The Journal of organic chemistry, 61 19
Y. Yoshizawa, A. Ametani, J. Tsunehiro, K. Nomura, M. Itoh, F. Fukui, S. Kaminogawa (1995)
Macrophage stimulation activity of the polysaccharide fraction from a marine alga (Porphyra yezoensis): structure-function relationships and improved solubility.Bioscience, biotechnology, and biochemistry, 59 10
S. Neves, M. Dias-Baruffi, A. Freitas, M. Roque-Barreira (2001)
Neutrophil migration induced in vivo and in vitro by marine algal lectinsInflammation Research, 50
N. Høiby (2002)
Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapies.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 1 4
S. Kiriyama, Yoko Okazaki, Akira Yoshida (1969)
Hypocholesterolemic effect of polysaccharides and polysaccharide-rich foodstuffs in cholesterol-fed rats.The Journal of nutrition, 97 3
P. Cáceres, M. Carlucci, E. Damonte, B. Matsuhiro, E. Zúñiga (2000)
Carrageenans from chilean samples of Stenogramme interrupta (Phyllophoraceae): structural analysis and biological activity.Phytochemistry, 53 1
M. Carlucci, M. Ciancia, M. Matulewicz, A. Cerezo, E. Damonte (1999)
Antiherpetic activity and mode of action of natural carrageenans of diverse structural types.Antiviral research, 43 2
Lee, Cheng, Lai, Shyu, Chen, Wu, Shih, Hsieh (1998)
Comparison between Intravenous Prostaglandin E2 and Extraamniotic Prostaglandin F2alpha Instillation for Termination in Second-Trimester Pregnancy.Journal of maternal-fetal investigation : the official journal of French Society of Ultrasound in Medicine and Biology ... [et al.], 8 3
J. Urones, P. Basabe, I. Marcos, J. Pineda, A. Lithgow, R. Moro, F. Palma, M.E.M. Arau´jo, M. Gravalos (1992)
Meroterpenes fromCystoseira usneoidesPhytochemistry, 31
R. Spieler (2002)
Seaweed compound's anti-HIV efficacy will be tested in southern AfricaThe Lancet, 359
J. Ara, V. Sultana, R. Qasim, V. Ahmad (2002)
Hypolipidaemic activity of seaweed from Karachi coastPhytotherapy Research, 16
T. Rasmussen, Mike Manefield, Jens Andersen, Leo Eberl, U. Anthoni, Carsten Christophersen, P. Steinberg, Staffan Kjelleberg, M. Givskov (2000)
How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1.Microbiology, 146 Pt 12
(2000)
stone: a randomized comparison between two misoprostol regimen. Hum. Reprod
R. Dalmo, J. Bøgwald, K. Ingebrigtsen, R. Seljelid (1996)
The immunomodulatory effect of laminaran [beta(1,3)-D-glucan] on Atlantic salmon, Salmo salar L., anterior kidney leucocytes after intraperitoneal, peroral and peranal administrationJournal of Fish Diseases, 19
H. El‐Refaey, A. Templeton (1995)
Pregnancy: Induction of abortion in the second trimester by a combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimensHuman Reproduction, 10
M. Serdula, G. Bartolini, Moore Re, J. Gooch, N. Wiebenga (1982)
Seaweed itch on windward Oahu.Hawaii medical journal, 41 7
F. Horgen, D. Santos, G. Goetz, B. Sakamoto, Y. Kan, H. Nagai, P. Scheuer (2000)
A new depsipeptide from the sacoglossan mollusk Elysia ornata and the green alga Bryopsis species.Journal of natural products, 63 1
R. Griffin, D. Rogers, P. Spencer-Phillips, L. Swain (1995)
Lectin from Codium fragile ssp. tomentosoides conjugated to colloidal gold: a new histochemical reagent.British journal of biomedical science, 52 3
A. Wu, J. Wu, W. Watkins, C. Chen, M. Tsai (1996)
Binding properties of a blood group Le(a+) active sialoglycoprotein, purified from human ovarian cyst, with applied lectins.Biochimica et biophysica acta, 1316 2
K. Bird, T. Chiles, R. Longley, A. Kendrick, M. Kinkema (1993)
Agglutinins from marine macroalgae of the southeastern United StatesJournal of Applied Phycology, 5
M. Laycock, A. Freitas, J. Wright (1989)
Glutamate agonists from marine algaeJournal of Applied Phycology, 1
W. Zhu, V. Ooi, P. Chan, P. Ang, A. Chapman, R. Anderson, V. Vreeland, I. Davison (2003)
Inhibitory effect of extracts of marine algae from Hong Kong against Herpes simplex viruses., 2001
W. Gerwick, P. Proteau, D. Nagle, M. Wise, Z. Jiang, M. Bernart, M. Hamberg (1993)
Biologically active oxylipins from seaweedsHydrobiologia, 260-261
D. Attaway, O. Zaborsky (1993)
Pharmaceutical and Bioactive Natural Products
Keisuke Watanabe, M. Miyakado, N. Ohno, A. Okada, K. Yanagi, Koichi Moriguchi (1989)
A polyhalogenated insecticidal monoterpene from the red alga, Plocamium telfairiaePhytochemistry, 28
Zaporozhets Ts, Besednova Nn, Eliakova La, Zviagintseva Tn, Krashevskiĭ Sv (1995)
The effect of translam on the immune response of irradiated miceRadiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk, 35
Da-lin Ren, H. Noda, H. Amano, T. Nishino, K. Nishizawa (1994)
Study on antihypertensive and antihyperlipidemic effects of marine algaeFisheries Science, 60
T. Ng, W. Li, H. Yeung (1989)
Effects of lectins with various carbohydrate binding specificities on lipid metabolism in isolated rat and hamster adipocytes.The International journal of biochemistry, 21 2
A. Wu, June Wu, W. Watkins, Chie-Pein Chen, Shuh-Chyung Song, Yuen-Yuen Chen (1998)
Differential binding of human blood group Sd(a+) and Sd(a−) Tamm‐Horsfall glycoproteins with Dolichos biflorus and Vicia villosa‐B4 agglutininsFEBS Letters, 429
J. Palermo, Patricia Flower, A. Seldes (1992)
Chondriamides A and B, new indolic metabolites from the red alga Chondria sp.Tetrahedron Letters, 33
Y. Ben-Ari, R. Cossart (2000)
Kainate, a double agent that generates seizures: two decades of progressTrends in Neurosciences, 23
E. Ito, H. Nagai (2000)
Bleeding from the small intestine caused by aplysiatoxin, the causative agent of the red alga Gracilaria coronopifolia poisoning.Toxicon : official journal of the International Society on Toxinology, 38 1
A. Mayer, V. Paul, W. Fenical, J. Norris, M. Carvalho, R. Jacobs (1993)
Phospholipase A2 inhibitors from marine algaeHydrobiologia, 260-261
J. Mullin, M. McGinn, K. Snock, S. Imaizumi (1990)
The effects of teleocidin and aplysiatoxin tumor promoters on epithelial tight junctions and transepithelial permeability: comparison to phorbol esters.Carcinogenesis, 11 3
In the last three decades the discovery of metabolites with biological activities from macroalgae has increased significantly. However, despite the intense research effort by academic and corporate institutions, very few products with real potential have been identified or developed. Based on Silverplatter MEDLINE and Aquatic Biology, Aquaculture & Fisheries Resources databases, the literature was searched for natural products from marine macroalgae in the Rhodophyta, Phaeophyta and Chlorophyta with biological and pharmacological activity. Substances that currently receive most attention from pharmaceutical companies for use in drug development, or from researchers in the field of medicine-related research include: sulphated polysaccharides as antiviral substances, halogenated furanones from Delisea pulchra as antifouling compounds, and kahalalide F from a species of Bryopsis as a possible treatment of lung cancer, tumours and AIDS. Other substances such as macroalgal lectins, fucoidans, kainoids and aplysiatoxins are routinely used in biomedical research and a multitude of other substances have known biological activities. The potential pharmaceutical, medicinal and research applications of these compounds are discussed.
Journal of Applied Phycology – Springer Journals
Published: Dec 26, 2004
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.