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/lp/de-gruyter/anti-invasive-effects-of-green-tea-polyphenol-epigallocatechin-3-04kZLvEmwl
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- Publisher
- de Gruyter
- Copyright
- Copyright © 2002 by the
- ISSN
- 1431-6730
- DOI
- 10.1515/BC.2002.010
- pmid
- 11928805
- Publisher site
- See Article on Publisher Site
Abstract
Abstract Several reports have attributed to green tea chemopreventive and therapeutic properties. Epidemiological studies have linked the regular use of green tea to a reduced incidence of breast and colon carcinomas. Tea contains several antioxidants, including polyphenols of the catechin (green tea) and theaflavin (black tea) groups. Green tea derivatives have been shown to act in vitro and in vivo as antiinflammatory, antiviral and antitumor drugs. Despite the extensive body of data only few studies have investigated the molecular mechanisms underlying these effects. In this brief review we focus on the inhibitory activity of catechins derived from green tea toward proteases involved in tumor invasion.
Journal
Biological Chemistry – de Gruyter
Published: Jan 23, 2002