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I. Räihä, O. Impivaara, M. Seppälä, Knuts Lr, L. Sourander (1993)
Determinants of symptoms suggestive of gastroesophageal reflux disease in the elderly.Scandinavian journal of gastroenterology, 28 11
C. North, Dana Downs, R. Clouse, A. Alrakawi, M. Dokucu, J. Cox, E. Spitznagel, D. Alpers (2004)
The presentation of irritable bowel syndrome in the context of somatization disorder.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2 9
V. Jochem, P. Fuerst, J. Fromkes (1992)
Familial Barrett's esophagus associated with adenocarcinoma.Gastroenterology, 102 4 Pt 1
D. Fleming (1993)
Morbidity registration and the fourth general practice morbidity survey in England and Wales.Scandinavian journal of primary health care. Supplement, 2
M. Rosaida, K. Goh (2004)
Gastro-oesophageal reflux disease, reflux oesophagitis and non-erosive reflux disease in a multiracial Asian population: a prospective, endoscopy based studyEuropean Journal of Gastroenterology & Hepatology, 16
J. Dent (1987)
Recent views on the pathogenesis of gastro-oesophageal reflux disease.Bailliere's clinical gastroenterology, 1 4
Trimble Trimble, Farouk Farouk, Pryde Pryde, Douglas Douglas, Heading Heading (1995)
Heightened visceral sensation in functional gastrointestinal disease is not site‐specific. Evidence for a generalized disorder of gut sensitivityDig Dis Sci, 40
G. Kjellén, L. Tibbling (1978)
Influence of body position, dry and water swallows, smoking, and alcohol on esophageal acid clearing.Scandinavian journal of gastroenterology, 13 3
S. Shohaimi, A. Welch, S. Bingham, R. Luben, N. Day, N. Wareham, K. Khaw (2004)
Residential area deprivation predicts fruit and vegetable consumption independently of individual educational level and occupational social class: a cross sectional population study in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk)Journal of Epidemiology and Community Health, 58
Zuo‐Feng Zhang, R. Kurtz, M. Sun, M. Karpeh, Guo-Pei Yu, N. Gargon, J. Fein, S. Georgopoulos, S. Harlap (1996)
Adenocarcinomas of the esophagus and gastric cardia: medical conditions, tobacco, alcohol, and socioeconomic factors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 5 10
J. Dent (1987)
1 Recent views on the pathogenesis of gastro-oesophageal reflux diseaseBaillière's clinical gastroenterology, 1
Daniel Winship, Carlton Caflisch, F. Zboralske, Walter Hogan (1968)
Deterioration of esophageal peristalsis in patients with alcoholic neuropathy.Gastroenterology, 55 2
H. El‐Serag, N. Petersen, J. Carter, D. Graham, Peter Richardson, R. Genta, L. Rabeneck (2004)
Gastroesophageal reflux among different racial groups in the United States.Gastroenterology, 126 7
Harland Winter, Kar Cheng, Carole Cummins, R. Maric, P. Silcocks, C. Varghese (1999)
Cancer incidence in the south Asian population of England (1990–92)British Journal of Cancer, 79
Dr. Trimble, R. Frcs, A. Hnc, S. BSc, R. Heading (1995)
Heightened visceral sensation in functional gastrointestinal disease is not site-specificDigestive Diseases and Sciences, 40
T. Kennedy, R. Jones (2000)
The prevalence of gastro‐oesophageal reflux symptoms in a UK population and the consultation behaviour of patients with these symptomsAlimentary Pharmacology & Therapeutics, 14
H. El‐Serag, A. Mason, N. Petersen, C. Key (2002)
Epidemiological differences between adenocarcinoma of the oesophagus and adenocarcinoma of the gastric cardia in the USAGut, 50
A. Scott, D. Pearce, P. Goldblatt (2001)
The sizes and characteristics of the minority ethnic populations of Great Britain--latest estimates.Population trends, 105
The basic skills agency
M. Nilsson, R. Johnsen, W. Ye, K. Hveem, J. Lagergren (2003)
Obesity and estrogen as risk factors for gastroesophageal reflux symptoms.JAMA, 290 1
M. Haque, J. Wyeth, N. Stace, N. Talley, R. Green (2000)
Prevalence, severity and associated features of gastro-oesophageal reflux and dyspepsia: a population-based study.The New Zealand medical journal, 113 1110
N. Trudgill, K. Kapur, S. Riley (1999)
Familial clustering of reflux symptomsAmerican Journal of Gastroenterology, 94
M. Díaz‐Rubio, C. Moreno-Elola-Olaso, E. Rey, G. Locke, F. Rodríguez‐Artalejo (2004)
Symptoms of gastro‐oesophageal reflux: prevalence, severity, duration and associated factors in a Spanish populationAlimentary Pharmacology & Therapeutics, 19
R. Fisher, G. Roberts, C. Grabowski, S. Cohen (1978)
Inhibition of lower esophageal sphincter circular muscle by female sex hormones.The American journal of physiology, 234 3
P. Kahrilas, R. Gupta (1989)
The effect of cigarette smoking on salivation and esophageal acid clearance.The Journal of laboratory and clinical medicine, 114 4
G. Dennish, D. Castell (1971)
Inhibitory effect of smoking on the lower esophageal sphincter.The New England journal of medicine, 284 20
M. Nilsson, G. Lundegårdh, L. Carling, W. Ye, J. Lagergren (2002)
Body Mass and Reflux Oesophagitis: an Oestrogen-dependent Association?Scandinavian Journal of Gastroenterology, 37
(1997)
Department of Health. Prescription Cost Analysis for England in 1996
S. Rajendra, K. Kutty, Norain Karim (2004)
Ethnic Differences in the Prevalence of Endoscopic Esophagitis and Barrett's Esophagus: The Long and Short of It AllDigestive Diseases and Sciences, 49
Dekel Dekel, Morse Morse, Fass Fass (2004)
The role of proton pump inhibitors in gastro‐oesophageal reflux diseaseDrugs, 64
J. Lagergren, R. Bergström, A. Lindgren, O. Nyrén (1999)
Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma.The New England journal of medicine, 340 11
Ms Brown, D. Silverman, Dr Pottern, Ms Schoenberg, Dr Greenberg, Dr Swanson, Dr Liff, D. Schwartz, Dr Hayes, Dr Blot, Dr Hoover (1994)
Adenocarcinoma of the esophagus and esophagogastric junction in White men in the United States: alcohol, tobacco, and socioeconomic factorsCancer Causes & Control, 5
Chnstiane Neumann, B. Cooper (1999)
Ethnic differences in gastro-oesophageal reflux disease.European journal of gastroenterology & hepatology, 11 7
G. Locke, N. Talley, S. Fett, A. Zinsmeister, L. Melton (1999)
Risk factors associated with symptoms of gastroesophageal reflux.The American journal of medicine, 106 6
A. Cameron, J. Lagergren, C. Henriksson, O. Nyrén, G. Locke, N. Pedersen (2001)
Gastroesophageal reflux disease in monozygotic and dizygotic twins.Gastroenterology, 122 1
W. Hirota, T. Loughney, D. Lazas, Corinne Maydonovitch, V. Rholl, R. Wong (1999)
Specialized intestinal metaplasia, dysplasia, and cancer of the esophagus and esophagogastric junction: prevalence and clinical data.Gastroenterology, 116 2
(1995)
Pathophysiology of gastroesophageal reflux disease: LES incompetence and esophageal clearance
W. Blot, S. Devesa, R. Kneller, J. Fraumeni (1991)
Rising incidence of adenocarcinoma of the esophagus and gastric cardia.JAMA, 265 10
W. Wong, K. Lai, K. Lam, W. Hui, Whc Hu, C. Lam, H. Xia, Jia Huang, C. Chan, S. Lam, B. Wong (2003)
Prevalence, clinical spectrum and health care utilization of gastro‐oesophageal reflux disease in a Chinese population: a population‐based studyAlimentary Pharmacology & Therapeutics, 18
J. Isolauri, P. Laippala (1995)
Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population.Annals of medicine, 27 1
G. Vitale, W. Cheadle, Bijesh Patel, S. Sadek, M. Michel, A. Cuschieri (1987)
The effect of alcohol on nocturnal gastroesophageal reflux.JAMA, 258 15
W. Hogan, S. Andrade, D. Winship (1972)
Ethanol-induced acute esophageal motor dysfunction.Journal of applied physiology, 32 6
W. Thompson, G. Longstreth, D. Drossman, W. Heaton, J. Irvine, A. Müller-Lissner, S. Müller-lissner, MD Thompson (1999)
Functional bowel disorders and functional abdominal painGut, 45
D. Black (1988)
HEALTH AND DEPRIVATION: Inequality and the northThe Journal of the Royal College of General Practitioners, 38
I. Mohammed, L. Cherkas, S. Riley, T. Spector, N. Trudgill (2003)
Genetic influences in gastro-oesophageal reflux disease: a twin studyGut, 52
B. Firoozi, K. Vega, B. Holland, M. Koliver, B. Trotman (1999)
Epidemiologic pattern of esophageal cancer at an inner-city university hospital.Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 10 2
Summary Aim: To examine the prevalence of gastro‐oesophageal reflux disease symptoms and potential risk factors among community subjects. Methods: A questionnaire was sent to 4000 subjects, stratified by age, gender and ethnicity to be representative of the local population. Gastro‐oesophageal reflux disease symptoms were defined as at least weekly heartburn or acid regurgitation. Results: 2231 responded (59%), 691 refused to participate and seven were incomplete. 1533 (41%) were evaluable (637 male, mean age 51 years, range: 20–80). The prevalence of gastro‐oesophageal reflux disease symptoms was 21%. Smoking, excess alcohol, irritable bowel syndrome, increasing body mass index, a family history of upper gastrointestinal disease, increasing Townsend deprivation index, anticholinergic drugs (all P < 0.0001), weight gain, antidepressant drugs, inhaled bronchodilators, no educational attainment (all P < 0.01), south Asian origin (P = 0.02) and manual work (P < 0.05) were associated with gastro‐oesophageal reflux disease symptoms. Multivariate logistic regression revealed increasing body mass index, a family history of upper gastrointestinal disease, irritable bowel syndrome, south Asian origin (all P < 0.0001), smoking, excess alcohol, no educational attainment and anticholinergic drugs (all P < 0.01) were independently associated with gastro‐oesophageal reflux disease symptoms. Conclusions: Frequent gastro‐oesophageal reflux disease symptoms affect 21% of the population. Increasing body mass index, a family history of upper gastrointestinal disease, irritable bowel syndrome, south Asian origin, smoking, excess alcohol, social deprivation and anticholinergic drugs are independently associated with gastro‐oesophageal reflux disease symptoms.
Alimentary Pharmacology & Therapeutics – Wiley
Published: Apr 1, 2005
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