In this issue of the Scandinavian Journal of Pain, our associate editor for medical statistics, Professor Eva Skovlund focuses on some of the important, and frequently misunderstood, basic issues of statistical analyses of medical research data .1The over-rated p-value is often misunderstoodp-values are always there in scientific publications from medical researchers. They impress reviewers, editors, and readers alike, more than they deserve. A low p-value is taken as a “proof” of the truth of the research-question, but the p-value only indicates the likelihood of finding the observed difference between treatments by random/by chance, even if there is no difference. Still, the observed difference can be of limited clinical relevance, in spite of a low p-value .2Effect-size and clinical significanceAs Eva Skovlund writes in her review : “a p-value does neither assess the size of an effect as such nor whether a statistically significant result is of any clinical relevance”.For clinically meaningful information from the statistical analyses, the size of the effect and its 95% confidence interval are needed.The effect-size is the difference between the observed value(s) and the expected value(s). If the null-hypothesis is true, i.e. that there is no difference between the therapies, the effect-size will be zero.
Scandinavian Journal of Pain – de Gruyter
Published: Dec 29, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera