Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Ingelfinger, P. Goldman (1976)
The serum digitalis concentration--does it diagnose digitalis toxicity?The New England journal of medicine, 294 16
P. Jannetto, N. Bratanow (2011)
Pain management in the 21st century: utilization of pharmacogenomics and therapeutic drug monitoringExpert Opinion on Drug Metabolism & Toxicology, 7
W. Stigelman, P. D. (1986)
Goodman and Gilman's the Pharmacological Basis of TherapeuticsMilitary Medicine, 151
B. Gidal, M. Pitterle, N. Spencer, Melissa Maly (1995)
Relationship between valproic acid dosage, plasma concentration and clearance in adult monotherapy patients with epilepsyJournal of Clinical Pharmacy and Therapeutics, 20
M. Avent, Benjamin Rogers, Allen Cheng, Allen Cheng, David Paterson (2011)
Current use of aminoglycosides: indications, pharmacokinetics and monitoring for toxicityInternal Medicine Journal, 41
D. Evered, C. Chapman (1971)
Plasma digoxin concentrations and digoxin toxicity in hospital patients.British Heart Journal, 33
N. Callaghan, R. Kenny, B. O’Neill, M. Crowley, T. Goggin (1985)
A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy.Journal of Neurology, Neurosurgery & Psychiatry, 48
E. Reynolds, Simon Shorvon, A. Galbraith, David Chadwick, C. Dellaportas, L. Vydelingum (1981)
Phenytoin Monotherapy for Epilepsy: A Long‐Term Prospective Study, Assisted by Serum Level Monitoring, in Previously Untreated PatientsEpilepsia, 22
L. Nežić, A. Derungs, M. Bruggisser, S. Tschudin-Sutter, S. Krähenbühl, M. Haschke (2014)
Therapeutic drug monitoring of once daily aminoglycoside dosing: comparison of two methods and investigation of the optimal blood sampling strategyEuropean Journal of Clinical Pharmacology, 70
Harold Booker, B. Darcey (1973)
Serum Concentrations of Free Diphenylhydantoin and their Relationship To Clinical IntoxicationEpilepsia, 14
F. Mármol (2006)
Litio: 55 años de historia en el tratamiento del trastorno bipolarMedicina Clinica, 127
R. Moore, P. Lietman, Craig Smith (1987)
Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration.The Journal of infectious diseases, 155 1
P. Ponikowski, A. Voors, S. Anker, H. Bueno, J. Cleland, Andrew Coats, V. Falk, J. González-Juanatey, V. Harjola, E. Jankowska, M. Jessup, C. Linde, P. Nihoyannopoulos, John Parissis, B. Pieske, Jillian Riley, Giuseppe Rosano, L. Ruilope, F. Ruschitzka, Frans Rutten, P. Meer (2016)
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failureEuropean Journal of Heart Failure, 18
C. Yancy, M. Jessup, B. Bozkurt, J. Butler, D. Casey, M. Drazner, G. Fonarow, S. Geraci, T. Horwich, J. Januzzi, Maryl Johnson, E. Kasper, W. Levy, F. Masoudi, P. Mcbride, J. McMurray, J. Mitchell, Pamela Peterson, B. Riegel, F. Sam, L. Stevenson, W. Tang, E. Tsai, B. Wilkoff (2013)
2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.Journal of the American College of Cardiology, 62 16
D. Bratzler, E. Dellinger, K. Olsen, T. Perl, P. Auwaerter, M. Bolon, D. Fish, D. Fish, L. Napolitano, R. Sawyer, D. Slain, J. Steinberg, R. Weinstein (2013)
Clinical practice guidelines for antimicrobial prophylaxis in surgery.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 70 3
A. Sundqvist, T. Tomson, B. Lundkvist (1997)
Pharmacokinetics of valproic acid in patients with juvenile myoclonic epilepsy on monotherapy.Therapeutic drug monitoring, 19 2
Josemir Sander (2004)
The Use of Antiepileptic Drugs—Principles and PracticeEpilepsia, 45
(2015)
Therapy , and Management of Complications
E. Woo, Y. Chan, Y. Yu, Y. Chan, C. Huang (1988)
If a Well‐Stabilized Epileptic Patient Has a Subtherapeutic Antiepileptic Drug Level, Should the Dose Be Increased? A Randomized Prospective StudyEpilepsia, 29
L. Gram, K. Bentsen, J. Parnas, H. Flachs (1982)
Controlled Trials in Epilepsy: A ReviewEpilepsia, 23
M. Tutor-Crespo, J. Hermida, J. Tutor (2007)
Phenytoin immunoassay measurements in serum samples from patients with renal insufficiency: comparison with high‐performance liquid chromatographyJournal of Clinical Laboratory Analysis, 21
L. Macle, J. Cairns, K. Leblanc, T. Tsang, A. Skanes, J. Cox, J. Healey, A. Bell, L. Pilote, J. Andrade, L. Mitchell, C. Atzema, D. Gladstone, Mike Sharma, Mike Sharma, S. Verma, S. Connolly, P. Dorian, R. Parkash, M. Talajic, S. Nattel, A. Verma (2016)
2016 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation.The Canadian journal of cardiology, 32 10
J. Cade (1949)
Lithium salts in the treatment of psychotic excitement.The Medical journal of Australia, 2 10
G. Hayes, Maria Kootsikas (1993)
Reassessing the Lower end of the Phenytoin Therapeutic Range: A Review of the LiteratureAnnals of Pharmacotherapy, 27
Med J Aust, 2
A. McShane, Dustin Bunch, Sihe Wang (2016)
Therapeutic drug monitoring of immunosuppressants by liquid chromatography-mass spectrometry.Clinica chimica acta; international journal of clinical chemistry, 454
G. Kumin (1980)
Clinical nephrotoxicity of tobramycin and gentamicin. A prospective study.JAMA, 244 16
L. Gram, H. Flachs, Annelise Wurtz‐Jørgensen, J. Parnas, B. Andersen (1979)
Sodium Valproate, Serum Level and Clinical Effect in Epilepsy: A Controlled StudyEpilepsia, 20
C. Hammett-Stabler, T. Johns (1998)
Laboratory guidelines for monitoring of antimicrobial drugsClinical Chemistry, 44
G. Zaccara, A. Messori, G. Muscas, F. Albani, A. Baruzzi, A. Bianchi, R. Riva, T. Valenza, P. Zagnoni, P. Zolo, R. Zappoli (1989)
Predictive performance of pharmacokinetic methods for phenytoin dosing: a multi-center evaluation in 282 patients with epilepsyEpilepsy Research, 3
N Engl J Med, 284
D. Touw, O. Graafland, A. Cranendonk, R. Vermeulen, M. Weissenbruch (2000)
Clinical pharmacokinetics of phenobarbital in neonates.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 12 2
M. Gitlin (2016)
Lithium side effects and toxicity: prevalence and management strategiesInternational Journal of Bipolar Disorders, 4
J. Kane (2002)
Extending indications for long-term pharmacotherapy: opportunities and challenges.The American journal of psychiatry, 159 1
P. Finley (2016)
Drug Interactions with Lithium: An UpdateClinical Pharmacokinetics, 55
M. Ehle, Chandni Patel, R. Giugliano (2011)
Digoxin: clinical highlights: a review of digoxin and its use in contemporary medicine.Critical pathways in cardiology, 10 2
Judy Peat, C. Frazee, U. Garg (2016)
Quantification of Free Phenytoin by Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS).Methods in molecular biology, 1383
R. Feldman, C. Pippenger (1976)
The Relation of Anticonvulsant Drug Levels to Complete Seizure ControlThe Journal of Clinical Pharmacology, 16
O. FæRØ, K. Kastrup, E. Nielsen, J. Melchior, I. Thorn (1972)
Successful Prophylaxis of Febrile Convulsions with PhenobarbitalEpilepsia, 13
J. Haroldson, Linda Kramer, D. Wolff, K. Lake (2000)
Elevated Free Fractions of Valproic Acid in a Heart Transplant Patient with Hypoalbuminemia, 34
R. Valdes (1985)
Endogenous digoxin-like immunoreactive factors: impact on digoxin measurements and potential physiological implications.Clinical chemistry, 31 9
B. Sallustio (2010)
LC-MS/MS for immunosuppressant therapeutic drug monitoring.Bioanalysis, 2 6
K. Traugott, P. Maxwell, Kay Green, C. Frei, James Lewis (2011)
Effects of therapeutic drug monitoring criteria in a computerized prescriber-order-entry system on the appropriateness of vancomycin level orders.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 68 4
P. Gooding, E. Berman, A. Lane, K. Agre (1976)
A review of results of clinical trials with amikacin.The Journal of infectious diseases, 134 SUPPL
Colin Lee, S. Walker, S. Walker, W. Seto, A. Simor, M. Jeschke (2017)
A prospective study evaluating tobramycin pharmacokinetics and optimal once daily dosing in burn patients.Burns : journal of the International Society for Burn Injuries, 43 8
B. Chan, N. Buckley (2014)
Digoxin-specific antibody fragments in the treatment of digoxin toxicityClinical Toxicology, 52
A. Lewis (1971)
Digitalis intoxication.Lancet, 2 7720
G. Schumacher, J. Barr, T. Browne, J. Collins (1991)
Test Performance Characteristics of the Serum Phenytoin Concentration (SPC): The Relationship Between SPC and Patient ResponseTherapeutic Drug Monitoring, 13
A. Gelbart, R. Hall, R. Goldman (1976)
DIGOXIN-INDUCED ARRHYTHMIAS IN HYPOKALÆMIAThe Lancet, 308
T. Iwamoto, Y. Kagawa, Y. Naito, S. Kuzuhara, M. Okuda (2006)
Clinical evaluation of plasma free phenytoin measurement and factors influencing its protein bindingBiopharmaceutics & Drug Disposition, 27
D. Haughey, G. Matzke, C. Halstenson, W. Keane (1984)
Analytical specificity of commercially available methods for serum phenytoin determination.Journal of analytical toxicology, 8 3
M. Rybak, B. Lomaestro, J. Rotschafer, R. Moellering, W. Craig, M. Billeter, J. Dalovisio, D. Levine (2009)
Therapeutic monitoring of vancomycin in adult patients: a consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 66 1
P. Patsalos, D. Berry, B. Bourgeois, J. Cloyd, T. Glauser, S. Johannessen, I. Leppik, T. Tomson, E. Perucca (2008)
Antiepileptic drugs—best practice guidelines for therapeutic drug monitoring: A position paper by the subcommission on therapeutic drug monitoring, ILAE Commission on Therapeutic StrategiesEpilepsia, 49
C. Hiemke, N. Bergemann, H. Clement, A. Conca, J. Deckert, K. Domschke, G. Eckermann, K. Egberts, M. Gerlach, C. Greiner, G. Gründer, E. Haen, U. Havemann-Reinecke, G. Hefner, R. Helmer, G. Janssen, E. Jaquenoud, G. Laux, T. Messer, R. Mössner, Matthias Müller, M. Paulzen, B. Pfuhlmann, P. Riederer, A. Saria, B. Schoppek, G. Schoretsanitis, M. Schwarz, M. Gracia, B. Stegmann, W. Steimer, J. Stingl, M. Uhr, S. Ulrich, S. Unterecker, R. Waschgler, G. Zernig, Gabriele Zurek, P. Baumann (2017)
Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017Pharmacopsychiatry, 51
S. Terra, J. Washam, G. Dunham, W. Gattis (1999)
Therapeutic Range of Digoxin's Efficacy in Heart Failure: What Is the Evidence?Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 19
M. Tutor-Crespo, J. Hermida, J. Tutor (2008)
Relative Proportions of Serum Carbamazepine and its Pharmacologically Active 10,11-Epoxy Derivative: Effect of Polytherapy and Renal InsufficiencyUpsala Journal of Medical Sciences, 113
Amanda Chuk, F. Saeed, Nadia Kousar, Susan Burrill, Barry Barns, Geoffrey Rickrode, J. Fu, Oleksandra Katrych, Patricia Saunders-Hao, C. Block, Tim Lahey (2015)
Variable pharmacokinetics of extended interval tobramycin or gentamicin among critically ill patients undergoing continuous venovenous hemofiltration.Clinical nephrology, 84 4
R. Machado-Vieira (2017)
Lithium, Stress, and Resilience in Bipolar Disorder: Deciphering this key homeostatic synaptic plasticity regulator.Journal of affective disorders, 233
U. Christians, A. Vinks, L. Langman, W. Clarke, P. Wallemacq, T. Gelder, Varun Renjen, P. Marquet, E. Meyer (2015)
Impact of Laboratory Practices on Interlaboratory Variability in Therapeutic Drug Monitoring of Immunosuppressive DrugsTherapeutic Drug Monitoring, 37
Schen Rj (1973)
Letter: Chlorpropamide hypoglycaemia.The Lancet, 2
S. Duffull, C. Kirkpatrick, E. Begg (2003)
Comparison of two Bayesian approaches to dose-individualization for once-daily aminoglycoside regimens.British journal of clinical pharmacology, 43 2
D. Turnbull, D. Howel, M. Rawlins, D. Chadwick (1985)
Which drug for the adult epileptic patient: phenytoin or valproate?British Medical Journal (Clinical research ed.), 290
Med Clin, 127
Y. Agrawal, H. Rennert (2012)
Pharmacogenomics and the future of toxicology testing.Clinics in laboratory medicine, 32 3
M. El-Dib, J. Soul (2017)
The use of phenobarbital and other anti-seizure drugs in newborns.Seminars in fetal & neonatal medicine, 22 5
J. Leis, J. Rutka, W. Gold (2015)
Aminoglycoside-induced ototoxicityCanadian Medical Association Journal, 187
J. Ezekowitz, E. O’Meara, M. McDonald, H. Abrams, Michael Chan, A. Ducharme, N. Giannetti, A. Grzeslo, P. Hamilton, G. Heckman, J. Howlett, S. Koshman, S. Lepage, R. McKelvie, G. Moe, M. Rajda, E. Swiggum, S. Virani, S. Zieroth, A. Al-hesayen, A. Cohen-Solal, M. D’Astous, S. De, E. Estrella-Holder, S. Fremes, L. Green, H. Haddad, K. Harkness, Adrian Hernandez, S. Kouz, M. Leblanc, F. Masoudi, H. Ross, A. Roussin, B. Sussex (2017)
2017 Comprehensive Update of the Canadian Cardiovascular Society Guidelines for the Management of Heart Failure.The Canadian journal of cardiology, 33 11
U. Garg, Judy Peat, C. Frazee, T. Nguyen, A. Ferguson (2013)
A Simple Isotope Dilution Electrospray Ionization Tandem Mass Spectrometry Method for the Determination of Free PhenytoinTherapeutic Drug Monitoring, 35
E. Perucca (2006)
Clinically relevant drug interactions with antiepileptic drugs.British journal of clinical pharmacology, 61 3
Paul LaPenna, L. Tormoehlen (2017)
The Pharmacology and Toxicology of Third-Generation Anticonvulsant DrugsJournal of Medical Toxicology, 13
R. Moellering (1994)
Monitoring serum vancomycin levels: climbing the mountain because it is there?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 18 4
R. Altena, J. Dijkstra, M. Meer, J. Howard, J. Kosterink, J. Kosterink, D. Soolingen, T. Werf, J. Alffenaar (2017)
Reduced Chance of Hearing Loss Associated with Therapeutic Drug Monitoring of Aminoglycosides in the Treatment of Multidrug-Resistant TuberculosisAntimicrobial Agents and Chemotherapy, 61
T. Smith, E. Haber (1970)
Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration.The Journal of clinical investigation, 49 12
F. Buchthal, O. Svensmark, H. Simonsen (1968)
Relation of eeg and seizures to phenobarbital in serum.Archives of neurology, 19 6
L. Baddour, W. Wilson, A. Bayer, V. Fowler, I. Tleyjeh, M. Rybak, B. Baršić, P. Lockhart, M. Gewitz, M. Levison, A. Bolger, J. Steckelberg, R. Baltimore, A. Fink, P. O'Gara, K. Taubert (2015)
Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart AssociationCirculation, 132
M. Ward, Mahmoud Musa, L. Bailey (1994)
Clinical Pharmacokinetics of LithiumThe Journal of Clinical Pharmacology, 34
Ther Drug Monit, 27
Ju‐Seop Kang, Min‐ho Lee (2009)
Overview of Therapeutic Drug MonitoringThe Korean Journal of Internal Medicine, 24
S. Johannessen, C. Landmark (2010)
Antiepileptic Drug Interactions - Principles and Clinical ImplicationsCurrent Neuropharmacology, 8
S. Livingston, W. Berman, L. Pauli (1975)
Anticonvulsant Drug Blood Levels: Practical Applications Based on 12 Years’ ExperienceJAMA, 232
M. Barras, D. Serisier, S. Hennig, Katrina Jess, R. Norris (2016)
Bayesian Estimation of Tobramycin Exposure in Patients with Cystic FibrosisAntimicrobial Agents and Chemotherapy, 60
E. Mohandas, V. Rajmohan (2007)
Lithium use in special populationsIndian Journal of Psychiatry, 49
B. Way, T. Wilhite, R. Miller, C. Smith, M. Landt (1998)
Vitros digoxin immunoassay evaluated for interference by digoxin-like immunoreactive factors.Clinical chemistry, 44 6 Pt 1
T. Annesley, D. McKeown, D. Holt, C. Mussell, E. Champarnaud, Leonie Harter, L. Calton, Donald Mason (2013)
Standardization of LC-MS for therapeutic drug monitoring of tacrolimus.Clinical chemistry, 59 11
Circulation, 128
F. Villanelli, E. Giocaliere, S. Malvagia, A. Rosati, Giulia Forni, S. Funghini, E. Shokry, D. Ombrone, M. Bona, R. Guerrini, G. Marca (2015)
Dried blood spot assay for the quantification of phenytoin using Liquid Chromatography-Mass Spectrometry.Clinica chimica acta; international journal of clinical chemistry, 440
R. Ahmed, Imelda Hannigan, H. MacDougall, R. Chan, G. Halmágyi (2012)
Gentamicin ototoxicity: a 23‐year selected case series of 103 patientsMedical Journal of Australia, 196
S. Lerner, B. Schmitt, R. Seligsohn, G. Matz (1986)
Comparative study of ototoxicity and nephrotoxicity in patients randomly assigned to treatment with amikacin or gentamicin.The American journal of medicine, 80 6B
A. Rhodes, Laura Evans, W. Alhazzani, Mitchell Levy, M. Antonelli, R. Ferrer, Anand Kumar, J. Sevransky, C. Sprung, M. Nunnally, B. Rochwerg, G. Rubenfeld, D. Angus, D. Annane, Richard Beale, Geoffrey Bellinghan, Gordon Bernard, J. Chiche, C. Coopersmith, Daniel Backer, Craig French, S. Fujishima, H. Gerlach, Jorge Hidalgo, S. Hollenberg, Alan Jones, Dilip Karnad, R. Kleinpell, Younsuk Koh, Thiago Lisboa, Flavia Machado, John Marini, John Marshall, J. Mazuski, L. McIntyre, Anthony McLean, S. Mehta, Rui Moreno, J. Myburgh, P. Navalesi, O. Nishida, Tiffany Osborn, A. Perner, Colleen Plunkett, M. Ranieri, Christa Schorr, Maureen Seckel, Christopher Seymour, L. Shieh, Khalid Shukri, Steven Simpson, M. Singer, B. Thompson, S. Townsend, Thomas Poll, J. Vincent, W. Wiersinga, Janice Zimmerman, R. Dellinger (2017)
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016Intensive Care Medicine, 43
(2005)
BerichtenPharmaceutisch weekblad, 3
F. Aucella, V. Lauriola, G. Vecchione, G. Tiscia, E. Grandone (2013)
Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.Journal of pharmaceutical and biomedical analysis, 86
N. Rifai, A. Horvath, C. Wittwer (2018)
Tietz textbook of clinical chemistry and molecular diagnostics
Sumeet Gupta, U. Khastgir (2017)
Drug information update. Lithium and chronic kidney disease: debates and dilemmasBJPsych Bulletin, 41
W. Duszynska, F. Taccone, M. Hurkacz, B. Kowalska-Krochmal, A. Wiela-Hojeńska, A. Kübler (2013)
Therapeutic drug monitoring of amikacin in septic patientsCritical Care, 17
T. Bailey, J. Little, B. Littenberg, R. Reichley, W. Dunagan (1997)
A meta-analysis of extended-interval dosing versus multiple daily dosing of aminoglycosides.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 24 5
Nikolas Hitiris, M. Brodie (2005)
Evidence‐based Treatment of Idiopathic Generalized Epilepsies with Older Antiepileptic DrugsEpilepsia, 46
S. Jortani, A. Pinar, N. Johnson, R. Valdes (1999)
Validity of unbound digoxin measurements by immunoassays in presence of antidote (Digibind).Clinica chimica acta; international journal of clinical chemistry, 283 1-2
P. Wolf (1994)
If clinical chemistry had existed then....Clinical chemistry, 40 2
M. Rybak, L. Albrecht, S. Boike, P. Chandrasekar (1990)
Nephrotoxicity of vancomycin, alone and with an aminoglycoside.The Journal of antimicrobial chemotherapy, 25 4
S. Egan, P. Murphy, J. Fennell, Sinéad Kelly, M. Hickey, Carolyn McLean, M. Pate, C. Kirke, Annette Whiriskey, N. Wall, Eddie McCullagh, Joan Murphy, T. Delaney (2012)
Using Six Sigma to improve once daily gentamicin dosing and therapeutic drug monitoring performanceBMJ Quality & Safety, 21
S. George, R. Braithwaite, E. Hughes (1994)
Digoxin Measurements following Plasma Ultrafiltration in Two Patients with Digoxin Toxicity Treated with Specific Fab FragmentsAnnals of Clinical Biochemistry, 31
G. Malhi, D. Gessler, T. Outhred (2017)
The use of lithium for the treatment of bipolar disorder: Recommendations from clinical practice guidelines.Journal of affective disorders, 217
N. Lampón, Fernando Pampin, J. Tutor (2012)
Investigation of possible interference by digoxin-like immunoreactive substances on the Architect iDigoxin CMIA in serum samples from pregnant women, and patients with liver disease, renal insufficiency, critical illness, and kidney and liver transplant.Clinical laboratory, 58 11-12
C. Seger, M. Shipkova, U. Christians, E. Billaud, Ping Wang, D. Holt, M. Brunet, P. Kunicki, T. Pawinski, L. Langman, P. Marquet, M. Oellerich, E. Wieland, P. Wallemacq (2016)
Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice: Recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Immunosuppressive Drug Scientific CommitteeTherapeutic Drug Monitoring, 38
M. Za’abi, Juhina Muqbali, K. Al-Waili (2014)
Sampling time and indications appropriateness for therapeutically monitored drugs at a teaching university hospital in OmanSaudi Pharmaceutical Journal : SPJ, 23
M. Shipkova, D. Hesselink, D. Holt, E. Billaud, T. Gelder, P. Kunicki, M. Brunet, K. Budde, M. Barten, P. Simone, E. Wieland, O. López, S. Masuda, C. Seger, N. Picard, M. Oellerich, L. Langman, P. Wallemacq, R. Morris, Carol Thompson, P. Marquet (2016)
Therapeutic Drug Monitoring of Everolimus: A Consensus ReportTherapeutic Drug Monitoring, 38
D. Touw, C. Neef, A. Thomson, A. Vinks (2005)
Cost-Effectiveness of Therapeutic Drug Monitoring: A Systematic ReviewTherapeutic Drug Monitoring, 27
Adriana Mika, P. Stepnowski (2016)
Current methods of the analysis of immunosuppressive agents in clinical materials: A review.Journal of pharmaceutical and biomedical analysis, 127
G. Perry, E. Brown, R. Thornton, T. Shiva, J. Hubbard, K. Reddy, J. Doherty, F. Cardello, A. Fast, M. Radford, J. Folger, G. Bhaskar, R. Zoble, Sridharan, R. Loungani, M. Gheorghiade, A. Hsieh, C. Tommaso, M. Mansuri, M. Guess, S. Akhtar, S. Wagner, K. Hagan, K. Mcintyre, P. Ruble, M. Moten, A. Riley, G. Pierpont, Anand, G. Patel, B. Puram, B. Eladasari, J. Karnegis, E. Gillie, M. Crawford, W. Graettinger, A. Shah, J. Sacco, M. Chaudhry, D. Dolen, N. Elsherif, S. BekheitSaad, E. Campos, J. Greene, Khanijo, U. Kumar, G. Mallis, S. Mookherjee, M. DibnerDunlap, S. Gupta, K. Danisa, U. Thadani, A. Tan, M. Rajachar, M. Amidi, M. Oreilly, C. Hassapoyannes, M. Davies, V. Kumar, D. Okerson, K. Ramanathan, B. Putatunda, A. Gollapudi, A. Montero, P. Mohanty, C. Lui, S. Thagirisa, R. Lee, T. Glatter, K. Bodine, D. Roberts, M. Bertoglio, G. Dennish, R. Sarma, G. Gregoratos, D. Rausch, W. Pitt, B. Kennelly, D. Fahrenholtz, R. Gordon, L. Horwitz, R. Rothbart, P. Nutting, L. Lutz, D. Copen, A. Rashkow, J. Babb, L. VanVoorhees, A. Silverman, M. Stillabower, A. Miller, H. NguyenPho, R. Safford, S. Fishman, J. Neiman, M. Stein, J. Dominguez, G. Abernathy, P. Nair, L. Goodman, T. Cook, W. Wickemeyer, D. Berkson, J. Mathew, H. Richman, D. Lubell, R. Lang, E. Zajac, R. Rosenstein, M. Silver, J. Shanes, K. Kelly, M. Pequignot, R. Campbell, P. Kirlin, D. Ziperman, D. Denny, L. Gamble, M. Weiss, P. Kaimal, R. Dhurandhar, H. Ventura, M. Godley, C. Pu, E. Schick, D. Barbour, D. Salmon, M. Goldstein, M. Effron, J. Fleg, K. Baughman, R. Weiss, K. Ericson, W. Sturrock, J. Heinsimer, G. Timmis, Shaler Smith, D. Shrestha, W. Duvernoy, J. Hickner, B. Lewis, T. OBrien, S. Yarows, H. Willens, D. Mast, T. Johnson, R. Rodeheffer, M. Siefert, L. Swenson, P. Denes, R. Gudapati, F. Charles, M. Rich, Beckham, W. Hamilton, P. Abele, D. Harper, R. O'Kelly, A. Forker, F. Kahl, B. Garrou, Te Klang, K. Popio, S. Mohiuddin, E. Pollak, A. Chiaramida, J. Gregory, L. Papa, J. Abrams, S. Ung, C. Jutila, R. Croke, S. Chiaramida, R. Lucariello, D. Rim, M. Goldberger, R. Kohn, S. Graham, E. Philbin, K. Sheesley, A. Nafziger, G. Macina, J. Hsueh, S. Zoneraich, A. Binder, C. Weinstein, J. Morrison, A. Cameron, E. Vanderbush, J. Brown, P. Pande, E. Lader, R. Kay, D. Bloomfield, T. Costantino, D. Heiselman, S. Radwany, Smith, R. Hobbs, T. Fraker, T. Frerking, A. Deleon, L. Christie, M. Toren, J. Grover, F. McBarron, D. Harris, R. McLean, L. Morris, J. Zatuchni, J. Boehmer, B. Clemson, H. Lipshutz, R. Small, R. Ufret, Je LugoRodriquez, A. Khan, M. Yousefian, G. Friesinger, D. Ely, J. Farmer, J. Young, R. Payne, R. Fowles, A. Lee, Y. Shalev, Albitar, G. Schroeder, L. Radant, T. Hankey, S. Rezkalla, D. Groden, K. Teo, D. Humen, D. Wong, P. Greenwood, T. Talibi, W. Hui, W. Klinke, M. Senaratne, M. Goeres, D. Hughes, M. Sayeed, D. Roth, Belenkie, D. Manyari, K. Borgersen, L. Read, D. Kinloch, R. Reid, N. Barber, B. Horner, G. Kenefick, R. Kuritzky, Imrie, K. Wagner, S. Rabkin, H. Mizgala, L. Tarry, A. Dodek, J. Kornder, T. Ashton, D. Barr, J. Dufton, R. Sweeny, A. Morris, R. Bessoudo, D. Marr, Milton, B. Thompson, Robinson, B. Sussex, M. Tobin, D. McMahon, D. Folkins, R. Crowell, L. Lalonde, C. Koilpillai, R. Hatheway, M. Oreilly, T. Machel, Hack, J. Stewart, P. Tanser, B. Sullivan, S. Hagar, B. Quinn, R. Davies, M. Baird, W. Williams, M. Lemay, L. Higginson, M. Turek, R. Sochowski, A. Weeks, M. Jacobs, R. Baigrie, M. DeVilla, G. Vértes, B. Bożek, J. Goode, A. Ricci, J. Swan, D. Fell, S. LevinoffRoth, J. Arnold, L. Patrick, R. Southern, C. Rinne, D. Brisbin, J. Deyoung, T. Baitz, S. Vizel, J. Minkowitz, P. Letarte, Y. Chan, K. Kwok, S. Nawaz, F. Ganjavi, L. Yao, J. Misterski, D. Raco, A. Hess, G. Kuruvilla, L. Silverberg, D. Borts, J. Fulop, M. Weingert, R. Carter, B. Sahay, J. Hickey, G. Lalonde, G. Gosselin, M. Bourassa, C. Goulet, M. Joyal, M. Méthé, G. Honos, D. Fitchett, A. Serpa, F. Sestier, G. Roberge, Y. Latour, C. Rondeau, D. Gossard, J. Lenis, R. Brossoit, L. Simard, F. Delage, P. Auger, D. Saulnier, P. Talbot, J. Beaudoin, J. Campeau, G. Pruneau, M. Tamilia, G. Boutros, B. Comeau, R. Starra, R. StHilaire, J. Veilleux, M. Mercier, J. Poulin, K. Maclellan, S. Lepage, J. Rouleau, N. Bruinsma, C. Lévesque, R. Delarochelliére, M. Leblanc, S. Kouz, G. Kiwan, M. LaForest, J. Brooks, G. Bouchard, P. Gervais, J. Brophy, J. Gagnon, N. Habib, A. Basu, A. Lutterodt, M. Khouri, R. Gorlin, D. Egan, R. Garg, S. Yusuf, T. Montague, T. Smith, J. Cohn, G. Dagenais, R. Davies, D. Johnstone, C. Fye, Sather, D. Deykin, G. Francis, J. Collins, W. Williford, B. Singh (1997)
The effect of digoxin on mortality and morbidity in patients with heart failure.The New England journal of medicine, 336 8
N. Lenn, M. Robertson (1992)
Clinical utility of unbound antiepileptic drug blood levels in the management of epilepsyNeurology, 42
A. Tunkel, R. Hasbún, A. Bhimraj, K. Byers, S. Kaplan, W. Scheld, D. Beek, T. Bleck, H. Garton, J. Zunt (2017)
2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
M. Burton, C. Ash, D. Hill, TaRee Handy, M. Shepherd, M. Vasko (1991)
A controlled trial of the cost benefit of computerized bayesian aminoglycoside administrationClinical Pharmacology & Therapeutics, 49
Murray Barclay, Evan Begg (1994)
Aminoglycoside toxicity and relation to dose regimen.Adverse drug reactions and toxicological reviews, 13 4
C. Llanos-Paez, S. Hennig, C. Staatz (2017)
Population pharmacokinetic modelling, Monte Carlo simulation and semi-mechanistic pharmacodynamic modelling as tools to personalize gentamicin therapyJournal of Antimicrobial Chemotherapy, 72
Joseph Alpert (2014)
To dig or not to dig.The American journal of medicine, 127 6
Katharine Gallop (2010)
Review article: Phenytoin use and efficacy in the EDEmergency Medicine Australasia, 22
J. Boeynaems, A. Leener, B. Dessars, Hector Villa-Lobos, J. Aubry, F. Cotton, P. Thiry (2004)
Evaluation of a new generation of plastic evacuated blood-collection tubes in clinical chemistry, therapeutic drug monitoring, hormone and trace metal analysisClinical Chemistry and Laboratory Medicine (CCLM), 42
H. Neels, A. Sierens, Kristine Naelaerts, S. Scharpe, G. Hatfield, W. Lambert (2004)
Therapeutic drug monitoring of old and newer anti-epileptic drugsClinical Chemistry and Laboratory Medicine (CCLM), 42
E. Grandjean, J. Aubry (2009)
Lithium: Updated Human Knowledge Using an Evidence-Based ApproachCNS Drugs, 23
K. Reinikainen, T. Keranen, T. Halonen, H. Komulainen, P. Riekkinen (1987)
Comparison of oxcarbazepine and carbamazepine: a double-blind studyEpilepsy Research, 1
Ramsey D’Souza, T. Rajji, B. Mulsant, B. Pollock (2011)
Use of Lithium in the Treatment of Bipolar Disorder in Late-LifeCurrent Psychiatry Reports, 13
Paul Wolf (2001)
Creativity and chronic disease. Vincent van Gogh (1853-1890).The Western journal of medicine, 175 5
G. McMillin, William Owen, T. Lambert, B. De, E. Frank, P. Bach, T. Annesley, W. Roberts (2002)
Comparable effects of DIGIBIND and DigiFab in thirteen digoxin immunoassays.Clinical chemistry, 48 9
R. Hayward, J. Harding, R. Molloy, L. Land, Kate Longcroft-Neal, D. Moore, J. Ross (2018)
Adverse effects of a single dose of gentamicin in adults: a systematic reviewBritish Journal of Clinical Pharmacology, 84
J. Gatell, J. Miguel, L. Zamora, V. Araujo, M. Bonet, M. Bohé, M. Anta, M. Farré, M. Elena, A. Ballesta, J. Marín (1983)
Comparison of the nephrotoxicity and auditory toxicity of tobramycin and amikacinAntimicrobial Agents and Chemotherapy, 23
Sijiu Shen, R. Elin, S. Soldin (2001)
Characterization of cross reactivity by carbamazepine 10,11-epoxide with carbamazepine assays.Clinical biochemistry, 34 2
G. Matzke, Wayne Burkle, R. Lucarotti (1983)
Gentamicin and Tobramycin Dosing Guidelines: An EvaluationAnnals of Pharmacotherapy, 17
A. Troupin, Linda Ojemann, Lawrence Halpern, C. Dodrill, R. Wilkus, P. Friel, P. Feigl (1977)
Carbamazepine—A double‐blind comparison with phenytoinNeurology, 27
C. Au, R. Branco, R. Tasker (2017)
Management protocols for status epilepticus in the pediatric emergency room: systematic review article.Jornal de pediatria, 93 Suppl 1
Benjamin Roin (2009)
Unpatentable Drugs and the Standards of PatentabilityIntellectual Property Law eJournal
A. Jenkins, A. Thomson, N. Brown, Yvonne Semple, C. Sluman, A. Macgowan, A. Lovering, P. Wiffen (2016)
Amikacin use and therapeutic drug monitoring in adults: do dose regimens and drug exposures affect either outcome or adverse events? A systematic review.The Journal of antimicrobial chemotherapy, 71 10
G. Ewy (2015)
Digoxin: The Art and Science.The American journal of medicine, 128 12
O. Ziff, D. Lane, Monica Samra, Michael Griffith, P. Kirchhof, G. Lip, R. Steeds, J. Townend, D. Kotecha (2015)
Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial dataThe BMJ, 351
J. Tauke, S. Goldstein, M. Gheorghiade (1994)
Digoxin for Chronic Heart Failure: A Review of the Randomized Controlled Trials With Special Attention to the PROVED and RADIANCE TrialsProgress in Cardiovascular Diseases, 37
G. Matzke, J. Cloyd, R. Sawchuk (1981)
Acute Phenytoin and Primidone Intoxication A Pharmacokinetic AnalysisThe Journal of Clinical Pharmacology, 21
Tex Rev, 87
O. Ziff, D. Kotecha (2016)
Digoxin: The good and the bad.Trends in cardiovascular medicine, 26 7
Collin Freeman, D. Nicolau, P. Belliveau, C. Nightingale (1997)
Once-daily dosing of aminoglycosides: review and recommendations for clinical practice.The Journal of antimicrobial chemotherapy, 39 6
AbstractTherapeutic drug monitoring (TDM) is used to manage drugs with a narrow window between effective and toxic concentrations. TDM involves measuring blood concentrations of drugs to ensure effective therapy, avoid toxicity and monitor compliance. Common drugs for which TDM is used include aminoglycosides for infections, anticonvulsants to treat seizures, immunosuppressants for transplant patients and cardiac glycosides to regulate cardiac output and heart rate. An essential element of TDM is the provision of accurate and clinically relevant reference intervals. Unlike most laboratory reference intervals, which are derived from a healthy population, TDM reference intervals need to relate to clinical outcomes in the form of efficacy and toxicity. This makes TDM inherently more difficult to develop as healthy individuals are not on therapy, so there is no “normal value”. In addition, many of the aforementioned drugs are old and much of the information regarding reference intervals is based on small trials using methods that have changed. Furthermore, individuals have different pharmacokinetics and drug responses, particularly in the context of combined therapies, which exacerbates the challenge of universal TDM targets. This focused review examines the origins and limitations of existing TDM reference intervals for common drugs, providing targets where possible based on available guidelines.
Diagnosis: Official Journal of the Society to Improve Diagnosis in Medicine (SIDM) – de Gruyter
Published: Jun 27, 2018
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.