Oral immediate and prolonged release oxycodone for safe and effective patient controlled analgesia after surgery Can opioid for acute postoperative pain be improved by adding a peripheral opioid antagonist?

Oral immediate and prolonged release oxycodone for safe and effective patient controlled... In this issue of the Scandinavian Journal of Pain Boel Niklasson and co-workers, report a pragmatic study on pain relief in patients after Caesarean Section (CS). They compared a regimen with oral immediate and prolonged release oxycodone with the standard of care at Karolinska University Hospital, Huddinge [1]. Standard of care at the time at Huddinge was intravenous (IV) morphine administered by nurses during the first 24 h after a CS and thereafter with codeine-containing tablets. Both groups received ibuprofen and paracetamol.1Pragmatic clinical studies and explanatory clinical studiesA pragmatic study seeks to find the best way to treat patients in a specific clinical situation, whereas an explanatory study seeks to find a causal relationship that has general validity outside the particular clinical situation being studied [2]. A pragmatic study like the present study [1], in which patients and those treating the patients and evaluating the outcomes were not blinded, will have a number of confounding factors, and the results may not be valid for other populations in other circumstances [2]. However, a pragmatic study can document that a new regimen of pain management is at least as effective and safe as the standard of care therapy used before. The http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Scandinavian Journal of Pain de Gruyter

Oral immediate and prolonged release oxycodone for safe and effective patient controlled analgesia after surgery Can opioid for acute postoperative pain be improved by adding a peripheral opioid antagonist?

Loading next page...
 
/lp/degruyter/oral-immediate-and-prolonged-release-oxycodone-for-safe-and-effective-yUHjHqkkFH
Publisher
De Gruyter
Copyright
© 2015 Scandinavian Association for the Study of Pain
ISSN
1877-8860
eISSN
1877-8879
D.O.I.
10.1016/j.sjpain.2015.01.007
Publisher site
See Article on Publisher Site

Abstract

In this issue of the Scandinavian Journal of Pain Boel Niklasson and co-workers, report a pragmatic study on pain relief in patients after Caesarean Section (CS). They compared a regimen with oral immediate and prolonged release oxycodone with the standard of care at Karolinska University Hospital, Huddinge [1]. Standard of care at the time at Huddinge was intravenous (IV) morphine administered by nurses during the first 24 h after a CS and thereafter with codeine-containing tablets. Both groups received ibuprofen and paracetamol.1Pragmatic clinical studies and explanatory clinical studiesA pragmatic study seeks to find the best way to treat patients in a specific clinical situation, whereas an explanatory study seeks to find a causal relationship that has general validity outside the particular clinical situation being studied [2]. A pragmatic study like the present study [1], in which patients and those treating the patients and evaluating the outcomes were not blinded, will have a number of confounding factors, and the results may not be valid for other populations in other circumstances [2]. However, a pragmatic study can document that a new regimen of pain management is at least as effective and safe as the standard of care therapy used before. The

Journal

Scandinavian Journal of Painde Gruyter

Published: Apr 1, 2015

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off