In this issue of the Scandinavian Journal of Pain, Di Pietro et al.  report some interesting findings concerning reorganization of the somatosensory cerebral cortex (S1) in subjects with chronic pain and having the diagnosis of complex regional pain syndrome (CRPS). The use of fMRI and PET to try to unravel central function or dysfunction, both as the cause and/or effect of chronic pain is a burgeoning field. We welcome more information that can help shed light on this area in patients using non-invasive investigation of brain function. CRPS continues to be poorly understood and with poor treatment outcomes despite the use of a wide spectrum of treatment modalities. Even though this is a small patient segment, it deserves more attention from researchers, both clinical and in the basic sciences.1Mini-review of diagnosis and treatment of CRPSLoss of function is common in CRPS. Abnormal sensory and motor findings are also common and form the basis for making the diagnosis of CRPS . Despite much interest and ongoing research, even using animal models, CRPS is poorly understood. Various treatment strategies have been reported but a subset of patients fail to respond to a wide variety of treatments including invasive (spinal cord
Scandinavian Journal of Pain – de Gruyter
Published: Dec 29, 2017
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