Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR AbstractAims. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR).Methods. 174 patients who had eGFR ≥ 60 mL/min/1.73 m2 were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated.Results. NLR was significantly higher (p < 0.05) in microalbuminuric patients (1.91 ± 0.70) compared with normoalbuminuric patients (1.63 ± 0.53). A positive correlation was found between urine albumin excretion and NLR in the whole study group (r = 0.214, p < 0.005).Conclusions. Higher NLR levels were found in microalbuminuric patients with normal eGFR. Also a significant positive correlation was observed between albuminuria and NLR. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Romanian Journal of Internal Medicine de Gruyter

Association of neutrophil-to-lymphocyte ratio and microalbuminuria in patients with normal eGFR

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Publisher
de Gruyter
Copyright
© 2017 Aysun Aybal Kutlugun et al., published by De Gruyter Open
eISSN
2501-062X
D.O.I.
10.1515/rjim-2017-0036
Publisher site
See Article on Publisher Site

Abstract

AbstractAims. The aim of this study was to evaluate the association between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and microalbuminuria in patients with normal estimated glomerular filtration rate (eGFR).Methods. 174 patients who had eGFR ≥ 60 mL/min/1.73 m2 were studied. Patients were divided into two groups according to the urinary albumin excretion as microalbuminuric group (n = 105) and normoalbuminuric group (n = 69). NLR and PLR levels were calculated.Results. NLR was significantly higher (p < 0.05) in microalbuminuric patients (1.91 ± 0.70) compared with normoalbuminuric patients (1.63 ± 0.53). A positive correlation was found between urine albumin excretion and NLR in the whole study group (r = 0.214, p < 0.005).Conclusions. Higher NLR levels were found in microalbuminuric patients with normal eGFR. Also a significant positive correlation was observed between albuminuria and NLR.

Journal

Romanian Journal of Internal Medicinede Gruyter

Published: Mar 1, 2018

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