To the Editor,Men and women differences are important in epidemiology, pathophysiology and treatment of type 2 diabetes mellitus (DM2). On the other hand, international position statements on diabetes care do not provide specific recommendations for females, except in the case of pregnant women .This is staggering if we think that women with DM2 carry 40% greater relative risk of coronary heart disease compared with men. The full explanation of the increased cardiovascular risk in diabetic women is far from being completely understood and many biological factors could be involved, like oxidative stress and antioxidant status.Chronic inflammation, together with oxidative stress, is a pivotal factor in the development of DM2 and the progression of vascular complications . Moreover, in DM2, a specific impairment in antioxidant capacity has been well described . It is important to go in depth in the association between gender and oxidative stress because oxidative stress is crucial in many diseases that differently affect males and females, DM2 and atherosclerosis in particular. Recently, gender differences in antioxidant enzyme subunits’ expression have been described, together with a different activity of these enzymes, between males and females . Although these studies have been mainly performed on animal or in
Clinical Chemistry and Laboratory Medicine (CCLM) – de Gruyter
Published: Mar 28, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera