In this issue of Scandinavian Journal of Pain Páll Karlsson and co-workers publish a study of the sensitivity and specificity of various methods for the diagnosis of small fibre impairment in patients with painful distal sensory polyneuropathies compared with healthy subjects . In more detail, they have compared results of quantitative sensory testing (QST) (including temperature thresholds), response on pain and local vasodilatation by topical application of capsaicin, and various morphological variables of skin biopsies, such as intraepidermal nerve fibre density (IENFD) and new measures such as small fibre axonal swellings and the epidermal and dermal nerve length density (eNFLD and dNFDL).1Improving diagnostic accuracy of painful distal sensory polyneuropathiesThe authors address in this report a very important question: how to improve the diagnostic accuracy of painful distal sensory polyneuropathy (DSP). Painful DSP is worldwide a large problem, affecting many millions of patients. Diabetes mellitus is the most common cause of neuropathy  and with a considerable world-wide increase in diabetes, the occurrence of diabetic neuropathy is increasing [2,3]. In addition, other diseases like hypothyroidism , HIV , connective tissue diseases , and a large variety of inherited diseases may be complicated by or manifested by a painful neuropathy .
Scandinavian Journal of Pain – de Gruyter
Published: Dec 29, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.
All for just $49/month
Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.
Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.
It’s easy to organize your research with our built-in tools.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera