Advances in understanding and treatment of opioid-induced-bowel-dysfunction, opioid-induced-constipation in particular Nordic recommendations based on multi-specialist input

Advances in understanding and treatment of opioid-induced-bowel-dysfunction,... In this issue of the Scandinavian Journal of Pain Helene Nordahl Christensen and her co-workers [1] and AsbjØrn Mohr Drewes and his co-workers [2] focus on the under-diagnosed, undertreated, and even inappropriately treated adverse effects on the gastrointestinal tract of opioids prescribed for relief of acute and long-lasting pain.1Opioids induce gastrointestinal dysfunction (OIBD), constipation in particular, and conventional laxatives may cause additional problems with negative effects on health-related quality of lifeNordahl Christensen et al. [1] with data from an Internet-based follow-up of patients who had been dispensed opioids for non-cancer pain, confirm that a majority of these patients suffer a significant burden of abdominal symptoms from opioid side effects. Their data confirm that there is a high degree of self management of opioid-induced constipation (OIC) with laxatives, and that there is a low degree of satisfaction with laxatives. Such adverse effects of opioids on functions of the gastrointestinal tract and the unsatisfactory self-management with laxatives contribute to a low health-related quality of life among patients with pain-conditions that are treated with opioids.2A Nordic multi-specialist working group for increased awareness of OIBD and advice on treatment of OIBDThere is a need for knowledge-based guidelines, or practice-advisory statements, on how to http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Scandinavian Journal of Pain de Gruyter

Advances in understanding and treatment of opioid-induced-bowel-dysfunction, opioid-induced-constipation in particular Nordic recommendations based on multi-specialist input

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Publisher
de Gruyter
Copyright
© 2016 Scandinavian Association for the Study of Pain
ISSN
1877-8860
eISSN
1877-8879
D.O.I.
10.1016/j.sjpain.2016.02.003
Publisher site
See Article on Publisher Site

Abstract

In this issue of the Scandinavian Journal of Pain Helene Nordahl Christensen and her co-workers [1] and AsbjØrn Mohr Drewes and his co-workers [2] focus on the under-diagnosed, undertreated, and even inappropriately treated adverse effects on the gastrointestinal tract of opioids prescribed for relief of acute and long-lasting pain.1Opioids induce gastrointestinal dysfunction (OIBD), constipation in particular, and conventional laxatives may cause additional problems with negative effects on health-related quality of lifeNordahl Christensen et al. [1] with data from an Internet-based follow-up of patients who had been dispensed opioids for non-cancer pain, confirm that a majority of these patients suffer a significant burden of abdominal symptoms from opioid side effects. Their data confirm that there is a high degree of self management of opioid-induced constipation (OIC) with laxatives, and that there is a low degree of satisfaction with laxatives. Such adverse effects of opioids on functions of the gastrointestinal tract and the unsatisfactory self-management with laxatives contribute to a low health-related quality of life among patients with pain-conditions that are treated with opioids.2A Nordic multi-specialist working group for increased awareness of OIBD and advice on treatment of OIBDThere is a need for knowledge-based guidelines, or practice-advisory statements, on how to

Journal

Scandinavian Journal of Painde Gruyter

Published: Apr 1, 2016

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