In this issue of the Scandinavian Journal of Pain Helene Nordahl Christensen and her co-workers  and AsbjØrn Mohr Drewes and his co-workers  focus on the under-diagnosed, undertreated, and even inappropriately treated adverse effects on the gastrointestinal tract of opioids prescribed for relief of acute and long-lasting pain.1Opioids induce gastrointestinal dysfunction (OIBD), constipation in particular, and conventional laxatives may cause additional problems with negative effects on health-related quality of lifeNordahl Christensen et al.  with data from an Internet-based follow-up of patients who had been dispensed opioids for non-cancer pain, confirm that a majority of these patients suffer a significant burden of abdominal symptoms from opioid side effects. Their data confirm that there is a high degree of self management of opioid-induced constipation (OIC) with laxatives, and that there is a low degree of satisfaction with laxatives. Such adverse effects of opioids on functions of the gastrointestinal tract and the unsatisfactory self-management with laxatives contribute to a low health-related quality of life among patients with pain-conditions that are treated with opioids.2A Nordic multi-specialist working group for increased awareness of OIBD and advice on treatment of OIBDThere is a need for knowledge-based guidelines, or practice-advisory statements, on how to
Scandinavian Journal of Pain – de Gruyter
Published: Apr 1, 2016
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