Transference of para-amino-hippurate from the mother to the amniotic fluid

Transference of para-amino-hippurate from the mother to the amniotic fluid Althabe et al., Transfcrence of para-amino-hippurate j. Perinat. Med. 4 (1976) 227 0. Althabe,G.Sabini,A.Basso,A.Fernändez, D. Torrado,R. Belitzky, R. CaldeyroBarcia Latin American Center for Perinatology and Human Development (PAHO/WHO), Department of Physiopathology, Medical Faculty, Montevideo, Uruguay To our knowledge there are few studies which analyze the time course of the concentration in amniotic fluid of alien substances administered to women during pregnancy. This is particularly true for those substances mainly cleared by the kidney into the urine. HANON et al. [7] gave orally para-amino-hippurate (PAH) to mothers during labor and found that about two hours later, the concentration of PAH in amniotic fluid was higher than that of maternal plasma. BRANDES et al. [4] showed that inulin passed from the mother to the fetus during late pregnancy but ROSA [9] administering this substance to the mother, could not find it in serial samples of amniotic fluid. Recently BASSO et al. [2] demonstrated that mannitol administered to the mother appears in amniotic fluid atincreasingconcentrationsreaching values higher than those found in simultaneous samples of maternal plasma. This type of studies may contribute to the knowledge of fetal renal function and its role in the formation of amniotic fluid, äs well äs http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Perinatal Medicine de Gruyter

Transference of para-amino-hippurate from the mother to the amniotic fluid

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Publisher
de Gruyter
Copyright
Copyright © 2009 Walter de Gruyter
ISSN
0300-5577
eISSN
1619-3997
DOI
10.1515/jpme.1976.4.4.227
Publisher site
See Article on Publisher Site

Abstract

Althabe et al., Transfcrence of para-amino-hippurate j. Perinat. Med. 4 (1976) 227 0. Althabe,G.Sabini,A.Basso,A.Fernändez, D. Torrado,R. Belitzky, R. CaldeyroBarcia Latin American Center for Perinatology and Human Development (PAHO/WHO), Department of Physiopathology, Medical Faculty, Montevideo, Uruguay To our knowledge there are few studies which analyze the time course of the concentration in amniotic fluid of alien substances administered to women during pregnancy. This is particularly true for those substances mainly cleared by the kidney into the urine. HANON et al. [7] gave orally para-amino-hippurate (PAH) to mothers during labor and found that about two hours later, the concentration of PAH in amniotic fluid was higher than that of maternal plasma. BRANDES et al. [4] showed that inulin passed from the mother to the fetus during late pregnancy but ROSA [9] administering this substance to the mother, could not find it in serial samples of amniotic fluid. Recently BASSO et al. [2] demonstrated that mannitol administered to the mother appears in amniotic fluid atincreasingconcentrationsreaching values higher than those found in simultaneous samples of maternal plasma. This type of studies may contribute to the knowledge of fetal renal function and its role in the formation of amniotic fluid, äs well äs

Journal

Journal of Perinatal Medicinede Gruyter

Published: Jan 1, 1976

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