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SHORT COMMUNICATION

SHORT COMMUNICATION Introduction In most clinical chemistry laboratories serum water is not routinely determined in the samples offered for analysis. However, there are circumstances where a knowledge of the water content is indispensable, for instance in order to differentiate between essential and pseudp-hyponatraemia. In this paper a new method for the determination of serum water is described and its accuracy is analysed. It was also investigated whether the serum protein concentration can be used to estimate the serum water content, as has been proposed in the literature (1). Serum water can be determined by evaporation, which is a lengthy process when performed in an oven at normal or reduced pressure. The operational time can be shortened considerably when the sample is placed in an infrared dryer, as shown recently (2). Another method would be to use a commercially available microwave oven for this purpose. This method has the advantage that it is quick (it takes less than 5 minutes to dry the sample to constant weight) and, depending on the volume and power generated in the oven, a considerable number of samples can be dried in one session. Results Material and Methods Evaporation was performed in a commercially available microwave http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine de Gruyter

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References (61)

Publisher
de Gruyter
Copyright
Copyright © 2009 Walter de Gruyter
ISSN
1434-6621
eISSN
1437-4331
DOI
10.1515/cclm.1988.26.9.579
Publisher site
See Article on Publisher Site

Abstract

Introduction In most clinical chemistry laboratories serum water is not routinely determined in the samples offered for analysis. However, there are circumstances where a knowledge of the water content is indispensable, for instance in order to differentiate between essential and pseudp-hyponatraemia. In this paper a new method for the determination of serum water is described and its accuracy is analysed. It was also investigated whether the serum protein concentration can be used to estimate the serum water content, as has been proposed in the literature (1). Serum water can be determined by evaporation, which is a lengthy process when performed in an oven at normal or reduced pressure. The operational time can be shortened considerably when the sample is placed in an infrared dryer, as shown recently (2). Another method would be to use a commercially available microwave oven for this purpose. This method has the advantage that it is quick (it takes less than 5 minutes to dry the sample to constant weight) and, depending on the volume and power generated in the oven, a considerable number of samples can be dried in one session. Results Material and Methods Evaporation was performed in a commercially available microwave

Journal

Clinical Chemistry and Laboratory Medicinede Gruyter

Published: Jan 1, 1988

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