Rapid Screening of Low Molecular Mass Proteinuria: Evaluation of the First Immunochemical Test Strip for the Detection of α 1 -Microglobulin in Urine

Rapid Screening of Low Molecular Mass Proteinuria: Evaluation of the First Immunochemical Test... Introduction fusion, and nephelometric techniques described for - , , . A laboratoryJ measurement of this protein are not suit0. t 4 Since' the , , of renal. tubular damage j often · not able as screening procedures /*\ 0· , ^^^ ' , onset . . , is /> (6). Simple «approaches, precededbyotherwarnmgsignsofrenaldysfunction, ^ ^ ^ Micral.Test strip for microalbuminuria it has been suggested that the measurement of low ^ which .g tQ an(J molecular mass proteins in urine should be used as , " , t« , ... * j * .· ,,, ^x suits, would be useful, an indicator of renal dysfunction (1, 2). Low molecular mass proteins such as ß2-microglobulin, retinol The objective of this study was to evaluate a recently binding protein, ribonuclease, and armicroglobulin developed immunochemical test strip for armicrohave been recommended as potential markers for globulin in urine as a means of detecting low molecdetecting this type of proteinuria, which is known as ular mass proteinuria. We assessed the possible distubular or low molecular mass proteinuria (3). Several crimination power of this test for normal and inauthors have reported the advantages of armicro- creased values of oti-microglobulin in urine by comglobulin http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine de Gruyter

Rapid Screening of Low Molecular Mass Proteinuria: Evaluation of the First Immunochemical Test Strip for the Detection of α 1 -Microglobulin in Urine

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Publisher
de Gruyter
Copyright
Copyright © 2009 Walter de Gruyter
ISSN
1434-6621
eISSN
1437-4331
DOI
10.1515/cclm.1993.31.10.683
Publisher site
See Article on Publisher Site

Abstract

Introduction fusion, and nephelometric techniques described for - , , . A laboratoryJ measurement of this protein are not suit0. t 4 Since' the , , of renal. tubular damage j often · not able as screening procedures /*\ 0· , ^^^ ' , onset . . , is /> (6). Simple «approaches, precededbyotherwarnmgsignsofrenaldysfunction, ^ ^ ^ Micral.Test strip for microalbuminuria it has been suggested that the measurement of low ^ which .g tQ an(J molecular mass proteins in urine should be used as , " , t« , ... * j * .· ,,, ^x suits, would be useful, an indicator of renal dysfunction (1, 2). Low molecular mass proteins such as ß2-microglobulin, retinol The objective of this study was to evaluate a recently binding protein, ribonuclease, and armicroglobulin developed immunochemical test strip for armicrohave been recommended as potential markers for globulin in urine as a means of detecting low molecdetecting this type of proteinuria, which is known as ular mass proteinuria. We assessed the possible distubular or low molecular mass proteinuria (3). Several crimination power of this test for normal and inauthors have reported the advantages of armicro- creased values of oti-microglobulin in urine by comglobulin

Journal

Clinical Chemistry and Laboratory Medicinede Gruyter

Published: Jan 1, 1993

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