Pharmacogenetics: From Bench to Bedside

Pharmacogenetics: From Bench to Bedside Introduction F. W. Frueh In this roundtable discussion, we will try to point out some of the necessary issues which bring pharmacogenetics from the research laboratories into the clinics, and, in particular, point out the actions required by various different entities involved in this process. Now, I thought that everybody will show pictures of Santorini, so I thought to show something else which is appropriate to launch this discussion (showing a Greek salad). The reason I’m showing you this is that genetics, including pharmacogenetics, is something that we are exposed to daily. But by looking at the genetic code, at the molecular level, we are now able to convey information to the patient, which so far we were not able to, and which can bear significant ethical consequences. However, everybody is, for instance, talking freely about their cholesterol level, and nobody thinks twice that this information contains genetic information. The lesson is that, as scientists and physicians, we have a lot to do to educate patients about the meaning and impact of everyday genetics. Financial aspects A study done by Decision Resources this year shows that genetic testing is accounted for by 10% pharmacogenomics- and 90% disease susceptibility-based http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine (CCLM) de Gruyter

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Publisher
de Gruyter
Copyright
Copyright © 2003 by the
ISSN
1434-6621
DOI
10.1515/CCLM.2003.092
pmid
12747610
Publisher site
See Article on Publisher Site

Abstract

Introduction F. W. Frueh In this roundtable discussion, we will try to point out some of the necessary issues which bring pharmacogenetics from the research laboratories into the clinics, and, in particular, point out the actions required by various different entities involved in this process. Now, I thought that everybody will show pictures of Santorini, so I thought to show something else which is appropriate to launch this discussion (showing a Greek salad). The reason I’m showing you this is that genetics, including pharmacogenetics, is something that we are exposed to daily. But by looking at the genetic code, at the molecular level, we are now able to convey information to the patient, which so far we were not able to, and which can bear significant ethical consequences. However, everybody is, for instance, talking freely about their cholesterol level, and nobody thinks twice that this information contains genetic information. The lesson is that, as scientists and physicians, we have a lot to do to educate patients about the meaning and impact of everyday genetics. Financial aspects A study done by Decision Resources this year shows that genetic testing is accounted for by 10% pharmacogenomics- and 90% disease susceptibility-based

Journal

Clinical Chemistry and Laboratory Medicine (CCLM)de Gruyter

Published: Apr 25, 2003

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