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Operationally simple green synthesis of some Schiff bases using grinding chemistry technique and evaluation of antimicrobial activities

Operationally simple green synthesis of some Schiff bases using grinding chemistry technique and... Abstract Operationally simple condensation of dl -alanine amino acid with substituted aromatic aldehydes/heterocyclic aldehyde occurs to afford Schiff bases in quantitative yield under organic solvent-free conditions efficiently in the presence of water as a green solvent. The operational simplicity, environmentally friendly conditions and high yield achieved are major benefits that meet the requirements of green production, including saving energy and high efficiency. Structural assignments are based on spectroscopic data. The compounds have also been screened for antibacterial and antifungal activities and most of the Schiff bases have shown potent antibac­terial and antifungal activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Green Processing and Synthesis de Gruyter

Operationally simple green synthesis of some Schiff bases using grinding chemistry technique and evaluation of antimicrobial activities

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Publisher
de Gruyter
Copyright
Copyright © 2012 by the
ISSN
2191-9542
eISSN
2191-9550
DOI
10.1515/gps-2012-0043
Publisher site
See Article on Publisher Site

Abstract

Abstract Operationally simple condensation of dl -alanine amino acid with substituted aromatic aldehydes/heterocyclic aldehyde occurs to afford Schiff bases in quantitative yield under organic solvent-free conditions efficiently in the presence of water as a green solvent. The operational simplicity, environmentally friendly conditions and high yield achieved are major benefits that meet the requirements of green production, including saving energy and high efficiency. Structural assignments are based on spectroscopic data. The compounds have also been screened for antibacterial and antifungal activities and most of the Schiff bases have shown potent antibac­terial and antifungal activity.

Journal

Green Processing and Synthesisde Gruyter

Published: Oct 1, 2012

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