van Wersch and Franke: Haemostaseological quantities after cerebral insult Eur. J. Clin. Chem. Clin. Biochem. Vol.31, 1993, pp. 575-578 © 1993 Waiter de Gruyter & Co. Berlin · New York By y. W. J. van Wersch' and C. L· Franke2 Haematological Laboratory Department of Neurology De Wever Hospital, Heerlen, The Netherlands (Received March 5/June 22, 1993) Summary: Thrombocytic, haemostatic and fibrinolytic quantities were investigated in 47 patients with cerebral infarction and 34 patients with cerebral haemorrhage. Sixteen of the infarction patients and ten patients of the haemorrhage group were on acetylsalicylic acid medication. Of the remaining 55 patients without acetylsalicylic medication 21/31 = 67.7% of the patients in the infarction group and 9/24 = 37.5% of the patients in the bleeding group had unphysiologically enhanced ADP-induced platelet aggregation. With regard to the coagulation and fibrinolysis markers no significant differences were found between the two groups. In both groups, coagulation activity markers (fibrin monomer and thrombin-antithrombin III), as well as Ddimers were significantly higher than in controls in a high proportion of cases. In 5/47 of the infarction patients and in 3/34 of the haemorrhage patients the fibrin monomer levels were elevated to such an extent, that it can
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1993
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