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Model based optimization of a novel ventricular assist device

Model based optimization of a novel ventricular assist device AbstractThis paper presents an optimization-based control scheme for a novel left ventricular assist device. This cardiac support system consists of two pumps connected in series and a buffer reservoir in between them. This novel concept for relieving the left ventricle is designed to allow the pre- and afterload on the heart to be explicitly adjusted and independently of each other. The first pump controls the preload of the heart with a known physiological controller. With an iterative model-based optimization, the afterload is minimized by the second pump while complying with all constraints. The proof of the control concept and a comparison to the classical single pump left-sided cardiac support is performed on a hardware-in-the-loop test bench. The results show that with the new left ventricular assist device concept, the afterload can be reduced compared to the classical cardiac support. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png at - Automatisierungstechnik de Gruyter

Model based optimization of a novel ventricular assist device

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Publisher
de Gruyter
Copyright
© 2021 Walter de Gruyter GmbH, Berlin/Boston
ISSN
2196-677X
eISSN
2196-677X
DOI
10.1515/auto-2021-0031
Publisher site
See Article on Publisher Site

Abstract

AbstractThis paper presents an optimization-based control scheme for a novel left ventricular assist device. This cardiac support system consists of two pumps connected in series and a buffer reservoir in between them. This novel concept for relieving the left ventricle is designed to allow the pre- and afterload on the heart to be explicitly adjusted and independently of each other. The first pump controls the preload of the heart with a known physiological controller. With an iterative model-based optimization, the afterload is minimized by the second pump while complying with all constraints. The proof of the control concept and a comparison to the classical single pump left-sided cardiac support is performed on a hardware-in-the-loop test bench. The results show that with the new left ventricular assist device concept, the afterload can be reduced compared to the classical cardiac support.

Journal

at - Automatisierungstechnikde Gruyter

Published: Jul 27, 2021

Keywords: optimal control; parameter estimation; modelica based modeling; left ventricular assist devices; Optimale Steuerung; Parameterschätzung; Modellierung in Modelica; Linksventrikuläres Unterstützungssystem

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