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Microwave-assisted reactions: Efficient and versatile one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones under controlled microwave heating

Microwave-assisted reactions: Efficient and versatile one-step synthesis of 8-substituted... AbstractWe report herein a simple and efficient one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones via reaction of 1,3-dimethyl-5,6-diaminouracil 1 with activated double bond systems 2 assisted by controlled microwave irradiation. The obtained heterocycles are privileged biologically relevant scaffolds. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Green Processing and Synthesis de Gruyter

Microwave-assisted reactions: Efficient and versatile one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones under controlled microwave heating

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Publisher
de Gruyter
Copyright
© 2021 Ramadan Ahmed Mekheimer et al., published by De Gruyter
ISSN
2191-9550
eISSN
2191-9550
DOI
10.1515/gps-2021-0014
Publisher site
See Article on Publisher Site

Abstract

AbstractWe report herein a simple and efficient one-step synthesis of 8-substituted xanthines and substituted pyrimidopteridine-2,4,6,8-tetraones via reaction of 1,3-dimethyl-5,6-diaminouracil 1 with activated double bond systems 2 assisted by controlled microwave irradiation. The obtained heterocycles are privileged biologically relevant scaffolds.

Journal

Green Processing and Synthesisde Gruyter

Published: Mar 12, 2021

Keywords: 8-substituted xanthines; pyrimidopetridines; 5,6-diaminouracil; green synthesis

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