Introduction Neonatal hyperbilirubinaemia is currently observed during the neonatal period (25 -r 50% of all neonates), mostly due to low activity of the hepatic glucuronosyltransferase (EC 220.127.116.11) (1). Total and conjugated (or "direct") bilirubin determinations are necessary to identify the origin of the jaundice, to predict its evolution and to treat it. Visible light phototherapy is one of the effective treatments frequently given to these children, but it produces photochemical prod- ucts (2) that may interfere with the biochemical methods commonly used for bilirubin determination (3). The aim of this study is to compare the data of total and conjugated bilirubin measured in neonates, undergoing phototherapy or not, using two commonly employed methods: colorimetric diazo reaction on a Hitachi 717, dual wavelength reflectance on a Kodak Ektachem 700. High performance liquid chromatograpfay was then used for further investigation. ,_ , Eur. J. Clin. Chera. din. Biochem. / Vol. 31,1993 / No. 8 Materials and Methods Patient samples Serum samples were from 108 neonates during the first 15 days of life (mean age: 4.7 days; range: 1-14 days), submitted to the laboratory for a survey of the bilirubin course. The gestational ages of the infants ranged from 26 to
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1993
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera