Introduction Curriculum vitae Dr. MATHIAS NELLE, M. D., was graduated from University Göttingen, Fed. Rep. of Germany, in 1986 and took the Boards in General Pediatrics in 1995. Since 1988, he has worked at the Department of Neonatology (Prof. Dr. med. Otwin Linderkamp), University of Heidelberg. Now he is mainly concerned with problems of systemic, cerebral and intestinal circulation in relation to rheologic parameters in premature infants andfullterm neonates. Specific projects concerned the role of placental blood transfer in circulation and postnatal adaptation, as well as effects of blood transfusion and volume expansion in anemic and hypovolemic neonates. In the normal human neonate, postnatal transfer of blood from the placenta to the neonate occurs if the newly born infant is kept at or below the level of the placenta and the umbilical cord is clamped at some time after 5 seconds of birth [10, 11, 18, 21]. Before birth, the full-term fetus has a blood volume of about 70 ml/kg and the placenta contains about 45 ml of blood per kg of fetal weight . If the umbilical cord is clamped three minutes after birth or later, 35 ml/kg may flow into the neonate [11, 21]. The rapid
Journal of Perinatal Medicine – de Gruyter
Published: Jan 1, 1996
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