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/lp/de-gruyter/effect-of-graded-doses-of-caesalpinia-bonducella-seed-extract-on-ovary-8pPHUV6NsW
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- Publisher
- de Gruyter
- Copyright
- Copyright © 2011 by the
- ISSN
- 0792-6855
- eISSN
- 2191-0286
- DOI
- 10.1515/jbcpp.2011.006
- pmid
- 22865364
- Publisher site
- See Article on Publisher Site
Abstract
Abstract Histological changes observed under light microscope illustrate follicular degeneration in ovary, vacuolation and mild disorganization of uterus on treatment with graded doses of alcohol seed extract of Caesalpinia bonducella . There was a significant decrease (p≤0.05) in duration of estrous cycle and mean ovarian weight. However, there were no uniform variations in mean uterine weight, serum estradiol and progesterone level. The results suggest that alcohol seed extract of C. bonducella has antiestrogenic property, possibly acting via inhibition of estrogen secretion.
Journal
Journal of Basic & Clinical Physiology & Pharmacology – de Gruyter
Published: Jun 1, 2011