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Diagnosis and prognosis of early rheumatoid arthritis, with special emphasis on laboratory analysis

Diagnosis and prognosis of early rheumatoid arthritis, with special emphasis on laboratory analysis Abstract Diagnosis of rheumatoid arthritis (RA) is mainly based on clinical criteria of symmetric polyarthritis of the hands and feet, with morning stiffness lasting usually more than 1h. Autoantibodies typical for RA, i.e., rheumatoid factors and anti-cyclic citrullinated peptide, and measurements of inflammation add more specific information, especially for early diagnosis, where clinical presentation may be oligosymptomatic involving only a few joints. These laboratory parameters are also relevant for prognosis of disease persistence, functional impairment and radiological progression. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine (CCLM) de Gruyter

Diagnosis and prognosis of early rheumatoid arthritis, with special emphasis on laboratory analysis

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Publisher
de Gruyter
Copyright
Copyright © 2006 by the
ISSN
1434-6621
eISSN
1437-4331
DOI
10.1515/CCLM.2006.026
pmid
16475897
Publisher site
See Article on Publisher Site

Abstract

Abstract Diagnosis of rheumatoid arthritis (RA) is mainly based on clinical criteria of symmetric polyarthritis of the hands and feet, with morning stiffness lasting usually more than 1h. Autoantibodies typical for RA, i.e., rheumatoid factors and anti-cyclic citrullinated peptide, and measurements of inflammation add more specific information, especially for early diagnosis, where clinical presentation may be oligosymptomatic involving only a few joints. These laboratory parameters are also relevant for prognosis of disease persistence, functional impairment and radiological progression.

Journal

Clinical Chemistry and Laboratory Medicine (CCLM)de Gruyter

Published: Feb 1, 2006

Keywords: arthritis; autoantibodies; cyclic citrullinated peptide; diagnosis; prognosis; C-reactive protein; rheumatoid arthritis; rheumatoid factor

References

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