Wood et al.: Tumour markers in renal transplant patients Eur. J. Glin. Chem. Clin. Biochem. Vol.31, 1993, pp. 75-82 © 1993 Walter de Gruyter & Co. Berlin · New York By W. G. Wood\ J. Sieinhoff2 and Anne-Christine Kessler3 Institut fiir Laboratoriumsdiagnostik, Klinikum der Hansestadt Stralsund, Stralsund Klinik für Innere Medizin, Medizinische Universität zu Lübeck, Lübeck Evaluation Department for Immunology Systems, Boehringer-Mannheim, Tutzing (Received July 15/October 26, 1992) Summary: Serial serum determinations of the tumour associated antigens carcinoembryonic antigen, tissue polypeptide antigen, CA 19-9, CA 15-3 and CA 125 were performed on 70 patients who were undergoing, or had undergone renal transplantation. The period of observation ranged from 4 days pre-operative to 708 days post-operative, although daily monitoring was usually carried out during the first 14--35 days post-operatively. With the exception of tissue polypeptide antigen, which was analysed with an immunoluminometric assay, all analytes were measured with the Enzymun-Test® System ES-300 using immunoenzymometric assays with colorimetric determination. The interassay coefficients of variation were less than 5% for the immunoenzymometric assays and 8.7% for tissue polypeptide antigen, all values being derived from 20 consecutive assays. Only 8/70 patients with no complications showed normal concentrations for all five analytes. 6/79
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1993
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