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/lp/bioscientifica/the-effect-of-housing-conditions-and-simple-experimental-procedures-cyW8zlNbNK
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- Publisher
- Bioscientifica
- Copyright
- Copyright © 1963 The Authors. All Rights Reserved.
- ISSN
- 0022-0795
- eISSN
- 1479-6805
- DOI
- 10.1677/joe.0.0260097
- Publisher site
- See Article on Publisher Site
Abstract
SUMMARYThe concentration of corticosterone in the plasma of rats has been determined by a spectrophotofluorimetric method.Animals housed in single cages, undisturbed for 18 hr. prior to testing show reproducible levels of 5·5 μg./100 ml. plasma. Rats housed in groups of 20 under the same conditions exhibit mean levels of 9·5 μg./100 ml.Non-specific stimuli such as environmental change, noise, handling, weighing and intraperitoneal injections all produce marked increases in plasma corticosterone levels which remain supernormal for at least 2 hr.The variation in the literature reports of 'resting' plasma corticosterone levels is discussed in the light of the present findings.
Journal
Journal of Endocrinology – Bioscientifica
Published: Mar 1, 1963