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RESPONSE OF X-IRRADIATED AND CRYPTORCHID TESTES TO ENDOGENOUS GONADOTROPHINS IN PARABIOTIC RATS

RESPONSE OF X-IRRADIATED AND CRYPTORCHID TESTES TO ENDOGENOUS GONADOTROPHINS IN PARABIOTIC RATS SUMMARYImmature male rats were (1) exposed to X-rays, or (2) made cryptorchid, or (3) subjected to a combination of the two and placed in parabiosis with castrated males. Pairs were autopsied at various intervals up to 46 weeks and effects upon gonads and accessory sex organs evaluated.Androgen production in response to endogenous gonadotrophins from a castrated animal is greater in irradiated than cryptorchid testes. The stresses imposed upon irradiated, intra-abdominal testes greatly reduces their capacity to produce androgen in response to gonadotrophins. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Endocrinology Bioscientifica

RESPONSE OF X-IRRADIATED AND CRYPTORCHID TESTES TO ENDOGENOUS GONADOTROPHINS IN PARABIOTIC RATS

Journal of Endocrinology , Volume 27 (2) – Oct 1, 1963

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Publisher
Bioscientifica
Copyright
Copyright © 1963 The Authors. All Rights Reserved.
ISSN
0022-0795
eISSN
1479-6805
DOI
10.1677/joe.0.0270193
Publisher site
See Article on Publisher Site

Abstract

SUMMARYImmature male rats were (1) exposed to X-rays, or (2) made cryptorchid, or (3) subjected to a combination of the two and placed in parabiosis with castrated males. Pairs were autopsied at various intervals up to 46 weeks and effects upon gonads and accessory sex organs evaluated.Androgen production in response to endogenous gonadotrophins from a castrated animal is greater in irradiated than cryptorchid testes. The stresses imposed upon irradiated, intra-abdominal testes greatly reduces their capacity to produce androgen in response to gonadotrophins.

Journal

Journal of EndocrinologyBioscientifica

Published: Oct 1, 1963

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