Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/bioscientifica/inhibitory-action-of-human-follicular-fluid-on-the-ovarian-wZYOvJBlLe
References
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
- Publisher
- Bioscientifica
- Copyright
- Copyright © 1978 The Authors. All Rights Reserved.
- ISSN
- 0022-0795
- eISSN
- 1479-6805
- DOI
- 10.1677/joe.0.0780161
- Publisher site
- See Article on Publisher Site
Abstract
Institute of Endocrinology, Chaim Sheba Medical Center, Tel Hashomer, Israel(Received 15 February 1978)Porcine follicular fluid has been shown to inhibit the gonadotrophin-stimulated accumulation of cyclic AMP in vitro (Ledwitz-Rigby, Gay, Stetson, Young & Channing, 1977). The aim of the present investigation was to test for cyclic AMP inhibitory activity in human follicular fluid obtained during the periovulatory period.Twelve normal, healthy subjects, aged 21-40 years, with regularovulatorycycles and requiring Iaparotomy for medical reasons, voluntarily consented to participate in the study. Laparotomy was scheduled as close as possible to the expected time of ovulation. With day 0 as the day of the operation, blood samples were taken daily on days −8 to −4 and three times/day on days −3 to 3 and the concentrations of follicle-stimulating hormone (FSH), luteinizing hormone (LH), oestradiol-17β and progesterone in the plasma were determined by radioimmunoassay (Lunenfeld, Insler, Eshkol & Birnboim, 1974). During Iaparotomy,
Journal
Journal of Endocrinology – Bioscientifica
Published: Jul 1, 1978