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/lp/bioscientifica/immunohistochemical-localization-of-kallikrein-within-the-prolactin-01pwq035Cq
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- Publisher
- Bioscientifica
- Copyright
- Copyright © 1990 The Authors. All Rights Reserved.
- ISSN
- 0022-0795
- eISSN
- 1479-6805
- DOI
- 10.1677/joe.0.1270317
- Publisher site
- See Article on Publisher Site
Abstract
ABSTRACTThe localization of tissue kallikrein in the pituitary gland of rats was investigated by an immunohistochemical technique using antiserum against rat urinary kallikrein. Kallikrein-positive cells were detected in the anterior lobe of the pituitary of both male and female rats, but were not observed in the posterior lobe of the pituitary in either sex.The kallikrein-positive cells in the anterior pituitary of female rats in oestrus were found to correspond to the prolactin-producing cells, whereas the cells producing GH, LH and ACTH were negative for kallikrein. It is possible, therefore, that the tissue kallikrein may be involved in the production of prolactin and not that of the other anterior pituitary hormones, such as GH, LH, FSH, ACTH and TSH.Journal of Endocrinology (1990) 127, 317–323
Journal
Journal of Endocrinology – Bioscientifica
Published: Nov 1, 1990