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/lp/bioscientifica/alkaline-phosphatase-and-glucuronidase-activity-in-the-rat-uterus-CakGcazAjy
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- Publisher
- Bioscientifica
- Copyright
- Copyright © 1966 The Authors. All Rights Reserved.
- ISSN
- 0022-0795
- eISSN
- 1479-6805
- DOI
- 10.1677/joe.0.0350385
- Publisher site
- See Article on Publisher Site
Abstract
SUMMARYUterine alkaline phosphatase and β-glucuronidase activity were assayed during the first 8 days of pregnancy in rats after unilateral tubal ligation and section. The results were as follows. Alkaline phosphatase increased in the pregnant horn from days 5 to 8 while the activity of the nonpregnant horn remained unaltered. This enhanced phosphatase activity was localized exclusively at the implantation sites. β-Glucuronidase steadily decreased during the first 8 days of pregnancy in both the gravid and non-gravid horns. The occurrence of a 'peak' in β-glucuronidase activity during the oestrogen surge on day 4 of pregnancy reported previously by Prahlad (1962) was not observed.The results are discussed in relation to an interaction between the implanting blastocyst and the hormonally conditioned uterus.
Journal
Journal of Endocrinology – Bioscientifica
Published: Aug 1, 1966