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Adrenal changes in genetically hypothyroid mice

Adrenal changes in genetically hypothyroid mice ABSTRACTThe adrenocortical X-zone was very poorly developed in young female mice homozygous for the hypothyroid, hyt, mutation, Feeding the mice thyroid powder resulted in the development of an X-zone. This subsequently degenerated in the same way as the X-zone found in the normal litter-mates of the mutants. We suggest that the adrenocortical effects may be due to changes in prolactin stimulation consequent upon the lack of response to thyrotrophin of the mutants.J. Endocr. (1984) 102, 277–280 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Endocrinology Bioscientifica

Adrenal changes in genetically hypothyroid mice

Shire, J. G. M.; Beamer, W. G.
Journal of Endocrinology , Volume 102 (3) – Sep 1, 1984
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Publisher
Bioscientifica
Copyright
Copyright © 1984 The Authors. All Rights Reserved.
ISSN
0022-0795
eISSN
1479-6805
DOI
10.1677/joe.0.1020277
Publisher site
See Article on Publisher Site

Abstract

ABSTRACTThe adrenocortical X-zone was very poorly developed in young female mice homozygous for the hypothyroid, hyt, mutation, Feeding the mice thyroid powder resulted in the development of an X-zone. This subsequently degenerated in the same way as the X-zone found in the normal litter-mates of the mutants. We suggest that the adrenocortical effects may be due to changes in prolactin stimulation consequent upon the lack of response to thyrotrophin of the mutants.J. Endocr. (1984) 102, 277–280

Journal

Journal of Endocrinology – Bioscientifica

Published: Sep 1, 1984

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