3 JAP Highlighted Series 4 Vascular Aging 1 2 7 Douglas R. Seals and Lacy M. Alexander 8 Department of Integrative Physiology, University of Colorado Boulder 9 Boulder, CO 80309, USA; Department of Kinesiology, The Pennsylvania 10 State University, University Park, PA 16802 15 Running Title: Vascular aging 18 Corresponding Author: 19 Douglas R. Seals, Ph.D. 20 University of Colorado Boulder 21 354 UCB 22 Boulder, CO 80309 23 Phone: 303-492-5305 24 Fax: 303-492-6778 25 email@example.com 26 27 Despite significant decreases in prevalence over the last 3 decades, 28 cardiovascular diseases (CVD) remain the leading causes of morbidity and mortality in 29 developed nations like the U.S. By far, the strongest independent risk factor for CVD is 30 age, with >90% of all CVD occurring in adults age 40 and older (1). Current population 31 projections of a doubling of the number of older adults over the coming decades 32 suggest the possibility of a marked increase in clinical CVD without effective 33 intervention (2). 34 Successful intervention efforts typically are aided by the identification of 35 therapeutic targets, which may attenuate or ameliorate age-related increases in our risk 36 of CVD. Direct effects of aging on the heart
Journal of Applied Physiology – The American Physiological Society
Published: May 22, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera