Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/annual_reviews/the-microbiome-and-human-biology-Z9pLthcwsH
References
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
- Publisher
- Annual Reviews
- Copyright
- Copyright 2017 by Annual Reviews. All rights reserved
- ISSN
- 1527-8204
- eISSN
- 1545-293X
- DOI
- 10.1146/annurev-genom-083115-022438
- pmid
- 28375652
- Publisher site
- See Article on Publisher Site
Abstract
Over the past few years, microbiome research has dramatically reshaped our understanding of human biology. New insights range from an enhanced understanding of how microbes mediate digestion and disease processes (e.g., in inflammatory bowel disease) to surprising associations with Parkinson's disease, autism, and depression. In this review, we describe how new generations of sequencing technology, analytical advances coupled to new software capabilities, and the integration of animal model data have led to these new discoveries. We also discuss the prospects for integrating studies of the microbiome, metabolome, and immune system, with the goal of elucidating mechanisms that govern their interactions. This systems-level understanding will change how we think about ourselves as organisms.
Journal
Annual Review of Genomics and Human Genetics – Annual Reviews
Published: Aug 31, 2017