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Process Principles for Large-Scale Nanomanufacturing

Process Principles for Large-Scale Nanomanufacturing Nanomanufacturing—the fabrication of macroscopic products from well-defined nanoscale building blocks—in a truly scalable and versatile manner is still far from our current reality. Here, we describe the barriers to large-scale nanomanufacturing and identify routes to overcome them. We argue for nanomanufacturing systems consisting of an iterative sequence of synthesis/assembly and separation/sorting unit operations, analogous to those used in chemicals manufacturing. In addition to performance and economic considerations, phenomena unique to the nanoscale must guide the design of each unit operation and the overall process flow. We identify and discuss four key nanomanufacturing process design needs: ( a ) appropriately selected process break points, ( b ) synthesis techniques appropriate for large-scale manufacturing, ( c ) new structure- and property-based separations, and ( d ) advances in stabilization and packaging. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Chemical and Biomolecular Engineering Annual Reviews

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Publisher
Annual Reviews
Copyright
Copyright © 2017 by Annual Reviews. All rights reserved
ISSN
1947-5438
eISSN
1947-5446
DOI
10.1146/annurev-chembioeng-060816-101522
pmid
28375773
Publisher site
See Article on Publisher Site

Abstract

Nanomanufacturing—the fabrication of macroscopic products from well-defined nanoscale building blocks—in a truly scalable and versatile manner is still far from our current reality. Here, we describe the barriers to large-scale nanomanufacturing and identify routes to overcome them. We argue for nanomanufacturing systems consisting of an iterative sequence of synthesis/assembly and separation/sorting unit operations, analogous to those used in chemicals manufacturing. In addition to performance and economic considerations, phenomena unique to the nanoscale must guide the design of each unit operation and the overall process flow. We identify and discuss four key nanomanufacturing process design needs: ( a ) appropriately selected process break points, ( b ) synthesis techniques appropriate for large-scale manufacturing, ( c ) new structure- and property-based separations, and ( d ) advances in stabilization and packaging.

Journal

Annual Review of Chemical and Biomolecular EngineeringAnnual Reviews

Published: Jun 7, 2017

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