The processes of cell division and cell death interact to generate the proper numbers and types of cells during development and to maintain this balance in the mature animal. The view that some cells die as a normal part of both development and homeostasis was established more than forty years ago (reviewed by Gliicksmann 1950). The precise function that naturallyÂ occurring cell death plays, the manner in which it is regulated, and the mechÂ anisms by which it occurs are currently subjects of intense research. Naturally-occurring cell death is found throughout the animal kingdom. In vertebrates, cell deaths have been observed in almost all tissues (Gliicksmann 1950) and have been studied most extensively in the develÂ oping nervous system (reviewed by Hamburger & Oppenheim 1982; Cowan et al 1984; Oppenheim 1991) and in the immune system (reviewed by Duvall & Wyllie 1986). Cell death also affects many different tissues during invertebrate development. In nematodes, neurons, muscle cells, epithelial cells, intestinal cells, and gonadal cells all can die during normal development (reviewed by Horvitz et al 1982; see also Sulston & Horvitz 1977; Sternberg & Horvitz 1981, 1982; SuIston et al 1983; Ellis & Horvitz 1986). Both muscle cell
Annual Review of Cell and Developmental Biology – Annual Reviews
Published: Nov 1, 1991
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera