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By YALE J. KATZ, PH.D., M.D.2 AND STANLEY Los Angeles, California R. BOURDO, M.D.3 Department of Medicine, University of Southern California, This review might better be titled, "Selected Topics in Chronic Pye lonephritis," since space limitations prevent treatment of several subtopics and numerous worthy studies. Several symposia, partly or wholly devoted to pyelonephritis, were held in recent years; their proceedings are in print or in press and are listed in the bibliography section of this paper. An excel lent review appeared in 1960 ( 1). PATHOLOGY Pathological criteria of chronic pyelonephritis have been re-examined by Kimmelstiel et al. (2) who conclude that an active pleomorphic inflamma tory infiltrate, particularly if accompanied by polymorphonuclear cells, is the safest criterion for the diagnosis of chronic pyelonephritis; other changes may be mimicked by other causes, particularly vascular disease. Thyroid like areas are not specific according to these authors as they may be seen in vascular disease, renal hypoplasia and dysplasia, and adjacent to expanding lesions such as renal cysts and tumors. Some marks by which these may be distinguished from pyelonephritis are noted. In 1959, Kimmelstiel (3) granted that periglomerular fibrosis in its proliferative stage with well-pre served glomerular tufts is
Annual Review of Medicine – Annual Reviews
Published: Feb 1, 1962
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