Vladimir Mironov a,b , Lieven De Veylder a , Marc Van Montagu a , and Dirk Inzé a,b,c a Laboratorium voor Genetica, Departement Plantenggenetica, Vlaams Interuniversitair Instituut voor Biotechnologie, Universiteit Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium b CropDesign N.V., Technologiepark 3, B-9052 Zwijnaarde, Belgium c Laboratoire Associé de l'Institut National de la Recherche Agronomique (France), Universiteit Gent, B-9000 Gent, Belgium Correspondence to: Dirk Inzé, email@example.com (E-mail), 32-9-2645349 (fax) INTRODUCTION TOP INTRODUCTION DIVERSITY OF CDKs AND... WHICH PLANT CDKs AND... HOW DOES CDK ACTIVITY... WHAT DO WE KNOW... FUNCTIONS? PERSPECTIVES REFERENCES Cell division is one of the most conspicuous features of life, and thus several elements of the control of cell division are common to both prokaryotes and eukaryotes (Amon 1998 ; Leatherwood 1998 ). The degree of evolutionary conservation is especially striking among eukaryotes, where progression through the successive phases of the cell cycle (S, G2, M, and G1) in species as diverse as yeast and humans is driven by a common class of heterodimeric serine/threonine protein kinases. These kinases consist of a catalytic subunit, termed cyclin-dependent kinase (CDK), and an activating subunit, cyclin (reviewed in Nigg 1995 ). The first indication that this commonality might extend
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