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KÃœRT R. ZINN,* AND MARK R. ELLERSIECK** SARAH MCELROY, T. JANEE. LINK, RICHARD DOWDY,' p. Department of Human Nutrition and Foods, *Missouri university Research Reactor, **Agricultural Experiment Station, University of Missouri, Columbia, MO 65211 transport although passive transport rmy also be decreased (8). Interactions between Ca and Mg have been re ported (9-21); however, the mechanisms of these in teractions remain unresolved. A positive interaction could be used to offset the decrease in Ca absorption with aging, thus reducing or delaying the increased incidence of osteoporosis seen with aging. A negative interaction would have important implications rel ative to dietary recommendations. The objective of this study was to evaluate the combined effects of age and Mg intake on the ab sorption and utilization of Ca as indicated by ap parent Ca absorption, whole body Ca retention, Ca balance, and bone mineral concentration. The metho dologies included a typical metabolic balance study and a metabolic trial using 47Ca as a radioactive tracer. ABSTRACT This study evaluates the effect of dietary magnesium concentration in rats of differing ages. Young (3 wk) and old (18 mo) Fischer 344 rats were fed the AIN-76A diet modified to contain either low (218 mg/kg) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Nutrition American Society for Nutrition

cit-title-group

Abstract

KÃœRT R. ZINN,* AND MARK R. ELLERSIECK** SARAH MCELROY, T. JANEE. LINK, RICHARD DOWDY,' p. Department of Human Nutrition and Foods, *Missouri university Research Reactor, **Agricultural Experiment Station, University of Missouri, Columbia, MO 65211 transport although passive transport rmy also be decreased (8). Interactions between Ca and Mg have been re ported (9-21); however, the mechanisms of these in teractions remain unresolved. A positive interaction could be used to offset the decrease in Ca absorption with aging, thus reducing or delaying the increased incidence of osteoporosis seen with aging. A negative interaction would have important implications rel ative to dietary recommendations. The objective of this study was to evaluate the combined effects of age and Mg intake on the ab sorption and utilization of Ca as indicated by ap parent Ca absorption, whole body Ca retention, Ca balance, and bone mineral concentration. The metho dologies included a typical metabolic balance study and a metabolic trial using 47Ca as a radioactive tracer. ABSTRACT This study evaluates the effect of dietary magnesium concentration in rats of differing ages. Young (3 wk) and old (18 mo) Fischer 344 rats were fed the AIN-76A diet modified to contain either low (218 mg/kg)
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