-
M.
Rubinstein,
S.
Pestka
(1981)
Purification and characterization of human leukocyte interferons by high-performance liquid chromatography.
Methods in enzymology, 78 Pt A
-
Z.
Marijanovic,
J.
Ragimbeau,
J.
Heyden,
G.
Uzé,
S.
Pellegrini
(2007)
Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.
The Biochemical journal, 407 1
-
M.
Chawla-Sarkar,
D.
Leaman,
E.
Borden
(2001)
Preferential Induction of Apoptosis by Interferon (IFN)-β Compared with IFN-α2
Clinical Cancer Research, 7
-
Diego
Jaitin,
L.
Roisman,
Eva
Jaks,
M.
Gavutis,
J.
Piehler,
J.
Heyden,
G.
Uzé,
G.
Schreiber
(2006)
Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.
Molecular and cellular biology, 26 5
-
A.
Raj,
A.
Oudenaarden
(2008)
Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences
Cell, 135
-
Chawla-Sarkar M.
(2001)
1821
Clin. Cancer Res., 7
-
Lei
Zheng,
U.
Baumann,
J.
Reymond
(2004)
An efficient one-step site-directed and site-saturation mutagenesis protocol.
Nucleic acids research, 32 14
-
K.
Pearce,
B.
Cunningham,
G.
Fuh,
T.
Teeri,
J.
Wells
(1999)
Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity.
Biochemistry, 38 1
-
C.
Hilkens,
J.
Schlaak,
I.
Kerr
(2003)
Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells 12
The Journal of Immunology, 171
-
D.
Leaman,
M.
Chawla-Sarkar,
B.
Jacobs,
Keyur
Vyas,
Yaping
Sun,
Aylin
Ozdemir,
T.
Yi,
B.
Williams,
E.
Borden
(2003)
Novel Growth and Death Related Interferon-Stimulated Genes (ISGs) in Melanoma: Greater Potency of IFN-β Compared with IFN-α2
Journal of Interferon and Cytokine Research, 23
-
L.
Pfeffer
(1997)
Biologic activities of natural and synthetic type I interferons.
Seminars in oncology, 24 3 Suppl 9
-
P.
Lemaire,
E.
Anderson,
J.
Lary,
J.
Cole
(2008)
Mechanism of PKR Activation by dsRNA.
Journal of molecular biology, 381 2
-
L.
Velazquez,
M.
Fellous,
G.
Stark,
S.
Pellegrini
(1992)
A protein tyrosine kinase in the interferon alpha/beta signaling pathway.
Cell, 70 2
-
B.
Damdinsuren,
H.
Nagano,
H.
Wada,
T.
Noda,
J.
Natsag,
S.
Marubashi,
A.
Miyamoto,
Y.
Takeda,
K.
Umeshita,
Y.
Doki,
K.
Dono,
M.
Monden
(2007)
Interferon alpha receptors are important for antiproliferative effect of interferon‐α against human hepatocellular carcinoma cells
Hepatology Research, 37
-
Pfeffer L. M
(1997)
S9
Semin. Oncol., 24
-
D.
Leaman,
M.
Chawla-Sarkar,
B.
Jacobs,
Keyur
Vyas,
Yaping
Sun,
Aylin
Ozdemir,
T.
Yi,
B.
Williams,
E.
Borden
(2003)
Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 23 12
-
L.
Cai,
N.
Friedman,
X.
Xie
(2006)
Stochastic protein expression in individual cells at the single molecule level
Nature, 440
-
J.
Newman,
Sina
Ghaemmaghami,
Jan
Ihmels,
David
Breslow,
M.
Noble,
J.
Derisi,
J.
Weissman
(2006)
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
Nature, 441
-
Georges
Lutfalla,
S.
Holland,
E.
Cinato,
D.
Monneron,
Jérôme
Reboul,
N.
Rogers,
J.
Smith,
G.
Stark,
Katheleen
Gardiner,
K.
Mogensen
(1995)
Mutant U5A cells are complemented by an interferon‐alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.
The EMBO Journal, 14
-
I.
Grumbach,
E.
Fish,
S.
Uddin,
B.
Majchrzak,
O.
Colamonici,
H.
Figulla,
A.
Heim,
L.
Platanias
(1999)
Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 19 7
-
Y.
Mitsui,
T.
Senda
(1997)
Elucidation of the basic three-dimensional structure of type I interferons and its functional and evolutionary implications.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 17 6
-
S.
Pestka,
Christopher
Krause,
Mark
Walter
(2004)
Interferons, interferon‐like cytokines, and their receptors
Immunological Reviews, 202
-
M.
Rosenblum,
W.
Yung,
P.
Kelleher,
F.
Ruzicka,
P.
Steck,
E.
Borden
(1990)
Growth Inhibitory Effects of Interferon-β but Not Interferon-α on Human Glioma Cells: Correlation of Receptor Binding, 2′,5′-O1igoadenylate Synthetase and Protein Kinase Activity
Journal of interferon research, 10
-
M.
Rani,
G.
Foster,
S.
Leung,
D.
Leaman,
G.
Stark,
R.
Ransohoff
(1996)
Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha.
The Journal of biological chemistry, 271 37
-
K.
Ito,
Hideo
Tanaka,
Takuo
Ito,
T.
Sultana,
T.
Kyo,
F.
Imanaka,
Y.
Ohmoto,
A.
Kimura
(2004)
Initial expression of interferon alpha receptor 2 (IFNAR2) on CD34‐positive cells and its down‐regulation correlate with clinical response to interferon therapy in chronic myelogenous leukemia
European Journal of Haematology, 73
-
T.
Wagner,
S.
Velichko,
Steven
Chesney,
S.
Biroc,
D.
Harde,
D.
Vogel,
E.
Croze
(2004)
Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors
International Journal of Cancer, 111
-
Interferons,
A.
Theofilopoulos,
R.
Baccala,
B.
Beutler,
D.
Kono
(2005)
TYPE I INTERFERONS (/) IN IMMUNITY AND AUTOIMMUNITY
-
G.
Uzé,
S.
Marco,
E.
Mouchel‐Vielh,
D.
Monneron,
M.
Bandu,
M.
Horisberger,
A.
Dorques,
G.
Lutfalla,
K.
Mogensen
(1994)
Domains of interaction between alpha interferon and its receptor components.
Journal of molecular biology, 243 2
-
L.
Platanias
(2005)
Mechanisms of type-I- and type-II-interferon-mediated signalling
Nature Reviews Immunology, 5
-
A.
Silva,
M.
Brickelmaier,
G.
Majeau,
A.
Lukashin,
J.
Peyman,
A.
Whitty,
P.
Hochman
(2002)
Comparison of gene expression patterns induced by treatment of human umbilical vein endothelial cells with IFN-alpha 2b vs. IFN-beta 1a: understanding the functional relationship between distinct type I interferons that act through a common receptor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22 2
-
Peter
Lamken,
S.
Lata,
M.
Gavutis,
J.
Piehler
(2004)
Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers.
Journal of molecular biology, 341 1
-
Melissa
Brierley,
E.
Fish
(2002)
Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 22 8
-
M.
Severa,
M.
Remoli,
E.
Giacomini,
J.
Ragimbeau,
R.
Lande,
G.
Uzé,
S.
Pellegrini,
E.
Coccia
(2006)
Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.
Journal of leukocyte biology, 79 6
-
L.
Manche,
S.
Green,
C.
Schmedt,
M.
Mathews
(1992)
Interactions between double-stranded RNA regulators and the protein kinase DAI
Molecular and Cellular Biology, 12
-
C.
Hilkens,
J.
Schlaak,
I.
Kerr
(2003)
Differential responses to IFN-alpha subtypes in human T cells and dendritic cells.
Journal of immunology, 171 10
-
A.
Theofilopoulos,
R.
Baccala,
B.
Beutler,
D.
Kono
(2005)
Type I interferons (alpha/beta) in immunity and autoimmunity.
Annual review of immunology, 23
-
Eva
Jaks,
M.
Gavutis,
G.
Uzé,
J.
Martal,
J.
Piehler
(2007)
Differential receptor subunit affinities of type I interferons govern differential signal activation.
Journal of molecular biology, 366 2
-
M.
Rosenblum,
W.
Yung,
P.
Kelleher,
F.
Ruzicka,
P.
Steck,
E.
Borden
(1990)
Growth inhibitory effects of interferon-beta but not interferon-alpha on human glioma cells: correlation of receptor binding, 2',5'-oligoadenylate synthetase and protein kinase activity.
Journal of interferon research, 10 2
-
Melissa
Brierley,
E.
Fish
(2002)
Review: IFN-α/β Receptor Interactions to Biologic Outcomes: Understanding the Circuitry
Journal of Interferon and Cytokine Research, 22
-
M.
Severa,
M.
Remoli,
E.
Giacomini,
J.
Ragimbeau,
R.
Lande,
G.
Uzé,
S.
Pellegrini,
E.
Coccia
(2006)
Differential responsiveness to IFN‐α and IFN‐β of human mature DC through modulation of IFNAR expression
Journal of Leukocyte Biology, 79
-
George
Stark,
I.
Kerr,
B.
Williams,
R.
Silverman,
R.
Schreiber
(1998)
How cells respond to interferons.
Annual review of biochemistry, 67
-
J.
Piehler,
G.
Schreiber
(1999)
Biophysical analysis of the interaction of human ifnar2 expressed in E. coli with IFNalpha2.
Journal of molecular biology, 289 1
-
Ignacio
Moraga,
D.
Harari,
G.
Schreiber,
G.
Uzé,
S.
Pellegrini
(2009)
Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities
Molecular and Cellular Biology, 29
-
Z.
Marijanovic,
J.
Ragimbeau,
J.
Heyden,
G.
Uzé,
S.
Pellegrini
(2007)
Comparable potency of IFNα2 and IFNβ on immediate JAK/STAT activation but differential down-regulation of IFNAR2
Biochemical Journal, 407
-
Michal
Slutzki,
Diego
Jaitin,
Tuval
Yehezkel,
G.
Schreiber
(2006)
Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity.
Journal of molecular biology, 360 5
-
M.
Marchetti,
M.
Monier,
Alexandre
Fradagrada,
K.
Mitchell,
Florence
Baychelier,
P.
Eid,
L.
Johannes,
C.
Lamaze
(2006)
Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors.
Molecular biology of the cell, 17 7
-
J.
Piehler,
L.
Roisman,
G.
Schreiber
(2000)
New Structural and Functional Aspects of the Type I Interferon-Receptor Interaction Revealed by Comprehensive Mutational Analysis of the Binding Interface*
The Journal of Biological Chemistry, 275
-
Eyal
Kalie,
Diego
Jaitin,
Renne
Abramovich,
G.
Schreiber
(2007)
An Interferon α2 Mutant Optimized by Phage Display for IFNAR1 Binding Confers Specifically Enhanced Antitumor Activities*
Journal of Biological Chemistry, 282
-
Diego
Jaitin,
L.
Roisman,
Eva
Jaks,
M.
Gavutis,
J.
Piehler,
J.
Heyden,
G.
Uzé,
G.
Schreiber
(2006)
Inquiring into the Differential Action of Interferons (IFNs): an IFN-α2 Mutant with Enhanced Affinity to IFNAR1 Is Functionally Similar to IFN-β
Molecular and Cellular Biology, 26
-
Roos G.
(1984)
2358
Cancer Res., 44
-
Fanli
Meng,
Jie-fei
Wang,
J.
Ge,
Xiaopeng
Fan,
B.
Wang,
L.
Han,
T.
Kisseleva,
Y.
Paik,
D.
Brenner,
Kai
Wang
(2011)
Alteration of Interferon-α/β Receptors in Chronic Hepatitis B Patients
Journal of Clinical Immunology, 31
-
Diego
Jaitin,
G.
Schreiber
(2007)
Upregulation of a small subset of genes drives type I interferon-induced antiviral memory.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 27 8
-
G.
Roos,
T.
Leanderson,
E.
Lundgren
(1984)
Interferon-induced cell cycle changes in human hematopoietic cell lines and fresh leukemic cells.
Cancer research, 44 6
-
C.
Cajean-Feroldi,
F.
Nosal,
P.
Nardeux,
X.
Gallet,
J.
Guymarho,
Florence
Baychelier,
P.
Sempé,
M.
Tovey,
J.
Escary,
P.
Eid
(2004)
Identification of residues of the IFNAR1 chain of the type I human interferon receptor critical for ligand binding and biological activity.
Biochemistry, 43 39
-
M.
Chawla-Sarkar,
D.
Leaman,
E.
Borden
(2001)
Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research, 7 6
-
S.
Jacobs,
E.
Hazum,
Y.
Shechter,
P.
Cuatrecasas
(1979)
Insulin receptor: covalent labeling and identification of subunits.
Proceedings of the National Academy of Sciences of the United States of America, 76 10
-
B.
Cohen,
D.
Novick,
S.
Barak,
M.
Rubinstein
(1995)
Ligand-induced association of the type I interferon receptor components
Molecular and Cellular Biology, 15
-
H.
Laude,
C.
Bonnardiere
(1984)
Cytocidal effect of interferons on porcine renal cells.
Journal of interferon research, 4 1
-
Eyal
Kalie,
Diego
Jaitin,
Yulia
Podoplelova,
J.
Piehler,
G.
Schreiber
(2008)
The Stability of the Ternary Interferon-Receptor Complex Rather than the Affinity to the Individual Subunits Dictates Differential Biological Activities*
Journal of Biological Chemistry, 283
-
J.
Claudinon,
M.
Monier,
C.
Lamaze
(2007)
Interfering with interferon receptor sorting and trafficking: impact on signaling.
Biochimie, 89 6-7
-
O.
Haller,
G.
Kochs,
F.
Weber
(2005)
The interferon response circuit: Induction and suppression by pathogenic viruses
Virology, 344
-
M.
Rani,
Graham
Foster,
S.
Leung,
D.
Leaman,
G.
Stark,
R.
Ransohoff
(1996)
Characterization of β-R1, a Gene That Is Selectively Induced by Interferon β (IFN-β) Compared with IFN-α*
The Journal of Biological Chemistry, 271
-
L.
Roisman,
Jacob
Piehler,
J.
Trosset,
H.
Scheraga,
G.
Schreiber
(2001)
Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking
Proceedings of the National Academy of Sciences of the United States of America, 98