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Relapsing Fever Problem of California

Relapsing Fever Problem of California STATISTICS concerning the incidence of in California (39 cases of which 16 were unproven by blood examination), its clinical features as well as a general discussion of the epidemiology, have recently been given by Briggs.' Aside from the work at the Hooper Foundation, University of California, as far as I know there has been no detailed study made of the California strains isolated from human cases and wild animals. My results, to a considerable extent, with discussions of the work and opinions of numerous authors throughout the world, have been embodied in 4 articles already published. In this paper I will review some of my outstanding conclusions regarding the California strains thus far studied. In general I may say that the morphological characteristics of the spirochete do not give us any criteria for the differentiation of species. The clinical disease in mice caused by the 8 California strains which I 2 have studied was practically identical in each except that some strains proved to be more virulent than others. As to the disease in guinea pigs there seems to be considerable difference in the clinical picture and in the individual susceptibility of these animals. While spirochetes are usually http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Public Health American Public Health Association

Relapsing Fever Problem of California

George E. Coleman
American Journal of Public Health , Volume 24 (10) – Oct 1, 1934
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Publisher
American Public Health Association
Copyright
Copyright © by the American Public Health Association
ISSN
0090-0036
eISSN
1541-0048
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Abstract

STATISTICS concerning the incidence of in California (39 cases of which 16 were unproven by blood examination), its clinical features as well as a general discussion of the epidemiology, have recently been given by Briggs.' Aside from the work at the Hooper Foundation, University of California, as far as I know there has been no detailed study made of the California strains isolated from human cases and wild animals. My results, to a considerable extent, with discussions of the work and opinions of numerous authors throughout the world, have been embodied in 4 articles already published. In this paper I will review some of my outstanding conclusions regarding the California strains thus far studied. In general I may say that the morphological characteristics of the spirochete do not give us any criteria for the differentiation of species. The clinical disease in mice caused by the 8 California strains which I 2 have studied was practically identical in each except that some strains proved to be more virulent than others. As to the disease in guinea pigs there seems to be considerable difference in the clinical picture and in the individual susceptibility of these animals. While spirochetes are usually

Journal

American Journal of Public Health – American Public Health Association

Published: Oct 1, 1934

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