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The relatively low incidence of coronary heart disease (CHD) among women in comparison with men is wellknown. However, mortality data for the U.S. population show more than 200,000 deaths annually ascribed to coronary disease among women and emphasize the public health importance of information on incidence and course of CHD among women as well as men. The large differentials in CHD incidence between men and women, documented in population studies,'-3 suggest questions the answers to which might provide insights into the pathogenesis of coronary heart disease. Once CHD has become clinically manifest in women, is its course similar to that in men? Are comparisons between the course of disease after myocardial infarction and that after diagnosis of similar in the two sexes? Are the same factors associated with favorable and unfavorable prognosis among men and women? As epidemiologic' data have accumulated, it has become clear that some factors are associated with an elevated risk for incidence of clinically manifest CHD in both women and men-for example, elevated serum cholesterol, hypertension, cigarette smoking.4 But the low incidence rates for CHD among women have restricted the number of studies which can develop data and limited the analysis of data on
American Journal of Public Health – American Public Health Association
Published: Jul 1, 1973
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