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Age at disease onset and pattern of cognitive impairment in probable Alzheimer's disease

Age at disease onset and pattern of cognitive impairment in probable Alzheimer's disease Factor analysis of cognitive scores from 150 patients with Alzheimer's disease yielded two orthogonal factors: one (Factor 1) loading high on spontaneous speech, repetition, comprehension, reading, writing, digit span, and left/right discrimination; the other (Factor 2) loading high on long-term memory, orientation, object naming, and abstraction. Regression analysis, controlled for education and disease duration, showed Factor 1 scores to be lower in early-onset patients and Factor 2 scores to be lower in late-onset patients. These data corroborate results reported by previous investigators and suggest that Alzheimer's disease is age-dependent and http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Neuropsychiatry & Clinical Neurosciences American Psychiatric Publishing, Inc (Journal)

Age at disease onset and pattern of cognitive impairment in probable Alzheimer's disease

Age at disease onset and pattern of cognitive impairment in probable Alzheimer's disease

Journal of Neuropsychiatry & Clinical Neurosciences , Volume 5 (1): 66 – Feb 1, 1993

Abstract

Factor analysis of cognitive scores from 150 patients with Alzheimer's disease yielded two orthogonal factors: one (Factor 1) loading high on spontaneous speech, repetition, comprehension, reading, writing, digit span, and left/right discrimination; the other (Factor 2) loading high on long-term memory, orientation, object naming, and abstraction. Regression analysis, controlled for education and disease duration, showed Factor 1 scores to be lower in early-onset patients and Factor 2 scores to be lower in late-onset patients. These data corroborate results reported by previous investigators and suggest that Alzheimer's disease is age-dependent and

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Publisher
American Psychiatric Publishing, Inc (Journal)
Copyright
Copyright © 1993 American Neuropsychiatric Association. All rights reserved.
ISSN
0895-0172
Publisher site
See Article on Publisher Site

Abstract

Factor analysis of cognitive scores from 150 patients with Alzheimer's disease yielded two orthogonal factors: one (Factor 1) loading high on spontaneous speech, repetition, comprehension, reading, writing, digit span, and left/right discrimination; the other (Factor 2) loading high on long-term memory, orientation, object naming, and abstraction. Regression analysis, controlled for education and disease duration, showed Factor 1 scores to be lower in early-onset patients and Factor 2 scores to be lower in late-onset patients. These data corroborate results reported by previous investigators and suggest that Alzheimer's disease is age-dependent and

Journal

Journal of Neuropsychiatry & Clinical NeurosciencesAmerican Psychiatric Publishing, Inc (Journal)

Published: Feb 1, 1993

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