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XERODERMA PIGMENTOSUM IN A NEGRESS

XERODERMA PIGMENTOSUM IN A NEGRESS Abstract The rarity of xeroderma pigmentosum in Negroes should be of sufficient interest to justify the report of a case in a Negress aged 19. Three cases of xeroderma pigmentosum in a family of African Negroes were described by Loewenthal and Trowell1 in 1938. In their report, of 5 children, aged 8, 7, 3½, 2½ and 1½ years, respectively, only 2 had escaped having the disease. The second and fifth were free of cutaneous manifestations. A striking similarity in the progress of the disease was present in all the cases. When the child was 1½ years old a pruritic pigmented eruption started on the face and soon spread to other parts of the body, resulting in pigmented and depigmented patches. Telangiectasis was not present. Ocular changes appeared soon after the onset, causing total blindness in the 2 older children and visual impairment in the youngest. Tumors of the tongue were References 1. Loewenthal, L. J. A., and Trowell, H. C.: Xeroderma Pigmentosum in African Negroes , Brit. J. Dermat. 50:66 ( (Feb.) ) 1938.Crossref 2. Hopkins, R., and Van Studdiford, M. T.: Multiple Epitheliomas and Pigmentary Dermatosis in Negro Boy , Arch. Dermat. & Syph. 29:408 ( (March) ) 1934. 3. Montgomery, H., and Reuter, M. J.: Xeroderma Pigmentosum: Report of Mild Case with Histopathologic Studies , Arch. Dermat. & Syph. 26:256 ( (Aug.) ) 1932. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1940 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1940.01490160030005
Publisher site
See Article on Publisher Site

Abstract

Abstract The rarity of xeroderma pigmentosum in Negroes should be of sufficient interest to justify the report of a case in a Negress aged 19. Three cases of xeroderma pigmentosum in a family of African Negroes were described by Loewenthal and Trowell1 in 1938. In their report, of 5 children, aged 8, 7, 3½, 2½ and 1½ years, respectively, only 2 had escaped having the disease. The second and fifth were free of cutaneous manifestations. A striking similarity in the progress of the disease was present in all the cases. When the child was 1½ years old a pruritic pigmented eruption started on the face and soon spread to other parts of the body, resulting in pigmented and depigmented patches. Telangiectasis was not present. Ocular changes appeared soon after the onset, causing total blindness in the 2 older children and visual impairment in the youngest. Tumors of the tongue were References 1. Loewenthal, L. J. A., and Trowell, H. C.: Xeroderma Pigmentosum in African Negroes , Brit. J. Dermat. 50:66 ( (Feb.) ) 1938.Crossref 2. Hopkins, R., and Van Studdiford, M. T.: Multiple Epitheliomas and Pigmentary Dermatosis in Negro Boy , Arch. Dermat. & Syph. 29:408 ( (March) ) 1934. 3. Montgomery, H., and Reuter, M. J.: Xeroderma Pigmentosum: Report of Mild Case with Histopathologic Studies , Arch. Dermat. & Syph. 26:256 ( (Aug.) ) 1932.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Oct 1, 1940

References

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